Results 91 to 100 of about 1,782,146 (327)

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still's Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens   +14 more
wiley   +1 more source

Epstein–Barr Virus and Hemophagocytic Lymphohistiocytosis

open access: yesFrontiers in Immunology, 2018
Epstein–Barr virus (EBV) is a ubiquitous virus that infects nearly all people worldwide without serious sequela. However, for patients who have genetic diseases which predispose them to the development of hemophagocytic lymphohistiocytosis (HLH), EBV ...
R. Marsh
semanticscholar   +1 more source

Protecting Anti-virus Programs From Viral Attacks [PDF]

open access: yesarXiv, 2013
During a fight between viruses and anti-viruses it is not always predictable that the anti-virus is going to win. There are many malicious viruses which target to attack and paralyze the anti-viruses. It is necessary for an anti-virus to detect and destroy the malware before its own files are detected and destroyed by the malware.
arxiv  

Expert Perspective: Diagnosis and Treatment of Castleman Disease

open access: yesArthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen   +2 more
wiley   +1 more source

The Epstein Barr virus circRNAome

open access: yesPLoS Pathogens, 2018
Our appreciation for the extent of Epstein Barr virus (EBV) transcriptome complexity continues to grow through findings of EBV encoded microRNAs, new long non-coding RNAs as well as the more recent discovery of over a hundred new polyadenylated lytic ...
Nathan Ungerleider   +14 more
semanticscholar   +1 more source

A simple approach to biophysical profiling of blood cells in extranodal NK/T cell lymphoma patients using deep learning‐integrated image cytometry

open access: yesBMEMat, EarlyView.
We developed a deep learning‐integrated image cytometry technique to profile biophysical attributes of blood cells from ENKTL patients. We demonstrate specific changes in cell size, eccentricity, and refractive index during treatment in a label‐free manner.
Seongcheol Park   +8 more
wiley   +1 more source

Abundant PD-L1 expression in Epstein-Barr Virus-infected gastric cancers

open access: yesOncoTarget, 2016
Gastric cancer (GC) is a deadly disease with limited treatment options. Recent studies with PD-1 inhibition have shown promising results in GC, but key questions remain regarding which GC subclass may respond best.
S. Derks   +12 more
semanticscholar   +1 more source

How do Viruses Attack Anti-Virus Programs [PDF]

open access: yesUmakant Mishra, "How do Viruses Attack Anti-virus Programs", TRIZsite Journal, June 2012, http://trizsite.tk/trizsite/articles/default.asp?month=Jun&year=2012, 2013
As the anti-viruses run in a trusted kernel level any loophole in the anti-virus program can enable attackers to take full control over the computer system and steal data or do serious damages. Hence the anti-virus engines must be developed with proper security in mind.
arxiv  

DNA Confinement drives uncoating of the HIV Virus [PDF]

open access: yes, 2014
We present a model for the uncoating of the HIV virus driven by forces exerted on the protein shell of HIV generated by DNA confinement.
arxiv   +1 more source

N6‐methyladenosine‐regulated exosome biogenesis orchestrates an immunosuppressive pre‐metastatic niche in gastric cancer peritoneal metastasis

open access: yesCancer Communications, EarlyView.
Abstract Background Gastric cancer peritoneal metastasis is clinically challenging, given the limited treatment options and poor prognosis. The molecular mechanisms that precede gastric cancer peritoneal metastasis, known as the pre‐metastatic niche (PMN), and its relationship with N6‐methyladenosine (m6A) modification remain unclear.
Song Li   +23 more
wiley   +1 more source

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