Results 121 to 130 of about 1,882,229 (349)

Epstein-Barr virus infection as a predisposing factor for multiple sclerosis. An update from molecular biology, immunology and epidemiology

Revista de la Facultad de Medicina, 2019
Introduction: Epstein-Barr virus is an infectious agent used to immortalize and induce polyclonal activation of B cells. It has been widely described that this virus produces changes in the cells it infects and in the immune response, and stimulates the ...
David López-Valencia, Ángela Medina-Ortega, Diego Fernando Hoyos-Samboní, Jhan Sebastián Saavedra-Torres, Carolina Salguero   +4 more
doaj   +1 more source

The emerging role of Epstein-Barr virus encoded microRNAs in nasopharyngeal carcinoma

Journal of Cancer, 2018
Epstein-Barr virus (EBV) is an oncogenic herpes virus that is closely associated with the initiation and development of nasopharyngeal carcinoma (NPC), lymphoma and other malignant tumors.
Chunmei Fan, Yanyan Tang, Jinpeng Wang, F. Xiong, Can Guo, Yumin Wang, Bo Xiang, Ming Zhou, Xiayu Li, Xu Wu, Yong Li, Xiaoling Li, Gui-yuan Li, W. Xiong, Zhaoyang Zeng   +14 more
semanticscholar   +1 more source

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

Eye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang, Xiaoyu Song, Fengxin Yang, Huhuifen He, Kun Zhao, Jingjing Qiu, Limei Cui, Qiang Zhang, Limei Liu, Yan Sun   +9 more
wiley   +1 more source

Epstein-Barr virus: Biology and clinical disease

Cell, 2022
B. Damania, S. Kenney, N. Raab-Traub
semanticscholar   +1 more source

Ephrin receptor A2 is a functional entry receptor for Epstein–Barr virus

Nature Microbiology, 2017
Epstein–Barr virus (EBV) is an oncogenic virus that infects more than 90% of the world’s population1. EBV predominantly infects human B cells and epithelial cells, which is initiated by fusion of the viral envelope with a host cellular membrane2.
Jia Chen, K. Sathiyamoorthy, Xianming Zhang, Samantha J Schaller, B. P. Perez White, T. Jardetzky, R. Longnecker   +6 more
semanticscholar   +1 more source

The regulated expression of Epstein-Barr virus. III. Proteins specified by EBV during the lytic cycle [PDF]

, 1981
The experiments show that 30 virus-induced or virus-specified proteins were synthesized in Raji cells after superinfection with Epstein-Barr virus (EBV) derived from P3HR1 cells. Using a combination of pulse labelling, application of cycloheximide blocks
Bayliss, G. J., Wolf, Hans J.
core   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Interleukin-10 Promotes cell proliferation in Epstein-Barr infected B cells through activation of Ras/ERK and phosphorylation of c-Myc [PDF]

, 2014
Epstein-Barr virus is a human herpes virus that in conjunction with Malaria is responsible for endemic Burkitt's lymphoma, a B-cell cancer. The main distinguishing characteristic of Burkitt's lymphoma is a constitutively active c-Myc protein.
NC DOCKS at The University of North Carolina at Greensboro, Smith, Jansen Barrett   +1 more
core  

Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming [PDF]

, 2013
Epstein-Barr virus (EBV) epigenetically reprogrammes B-lymphocytes to drive immortalization and facilitate viral persistence. Host-cell transcription is perturbed principally through the actions of EBV EBNA 2, 3A, 3B and 3C, with cellular genes ...
A Calender, A Chen, A Chen, A Le Roux, A Mor, A Rada-Iglesias, A Saha, A Sjoblom, A Smith, Aaron Arvey, Aditi Kanhere, AJ Sinclair, B Akhtar-Zaidi, B Kempkes, B Tomkinson, B Tomkinson, B Zhao, B Zhao, B Zhao, B Zhao, Bettina Kempkes, C Kaiser, C Kintner, C Subramanian, C. David Wood, CD Gregory, CF Eisenbeis, D Marshall, D Portal, D Wang, DY Wu, DY Wu, E Anderton, E Johannsen, EM Fuentes-Panana, EO Long, ES Robertson, F Lu, F Nitsche, F Wang, F Wang, F Wang, G Chinnadurai, G Laux, GL Kelly, H Ben-Bassat, Helen M. Webb, I Tempera, J O'Nions, JC Knutson, JI Cohen, JI Cohen, JI Cohen, JM Boyd, JS Knight, K Paschos, K Paschos, KG Krauer, L Skalska, L Skalska, L Waltzer, L Waltzer, L Wang, LC Spender, LC Spender, M Bain, M Bulger, M Cordier, M Hickabottom, M Wade, M Woisetschlaeger, MA Epstein, Marie L. Harth-Hertle, MB Gerstein, Michael J. McClellan, Michelle J. West, MJ Maunders, MJ McClellan, MJ West, ML Hertle, MM Pomerantz, MP Creyghton, N Ahmadiyeh, N Naumova, ND Heintzman, Opeoluwa Ojeniyi, P Nurse, PA Nikitin, Paul M. Lieberman, R Touitou, RD Palermo, RE White, RE White, Richard D. Palermo, Richard G. Jenner, S Banerjee, S Harada, S Maier, S Maruo, S Maruo, S Maruo, S Paliwal, S Tuupanen, SA Radkov, SJ Bark-Jones, SN Schlick, SR Grossman, T Choudhuri, T Henkel, Tim J. Cooper, U Schaeper, U Zimber-Strobl, VS Chopra, W Lucchesi, X Tong, X Tong, X Tong, Y Zhang   +117 more
core   +3 more sources

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

Glia, EarlyView.
Multiple sclerosis involves chronic CNS inflammation and neurodegeneration. This review highlights glial cells as key drivers in progressive MS, focusing on lesion pathology, molecular dysfunction, and human‐relevant model systems. ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive ...
Volker Siffrin
wiley   +1 more source