Results 61 to 70 of about 1,782,146 (327)

Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B

open access: yesAdvanced Science, EarlyView.
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang   +8 more
wiley   +1 more source

Proposed modifications and incorporation of plasma Epstein‐Barr virus DNA improve the TNM staging system for Epstein‐Barr virus‐related nasopharyngeal carcinoma

open access: yesCancer, 2018
The prognosis of patients who have Epstein‐Barr virus (EBV)‐related nasopharyngeal carcinoma (NPC) in which the tumor tissues harbor EBV have a better prognosis than those without EBV‐related NPC.
R. Guo   +12 more
semanticscholar   +1 more source

Modeling and Analysis of a Coupled SIS Bi-Virus Model [PDF]

open access: yesarXiv, 2022
The paper deals with the setting where two viruses (say virus 1 and virus 2) coexist in a population, and they are not necessarily mutually exclusive, in the sense that infection due to one virus does not preclude the possibility of simultaneous infection due to the other.
arxiv  

Global properties of an age-structured virus model with saturated antibody immune response, multi-target cells and general incidence rate [PDF]

open access: yesBolet\'in de la Sociedad Matem\'atica Mexicana, Vol. 27 (2021) 26, 2017
Some viruses, such as human immunodeficiency virus, can infect several types of cell populations. The age of infection can also affect the dynamics of infected cells and production of viral particles. In this work, we study a virus model with infection-age and different types of target cells which takes into account the saturation effect in antibody ...
arxiv   +1 more source

Immune-checkpoint expression in Epstein-Barr virus positive and negative plasmablastic lymphoma: a clinical and pathological study in 82 patients

open access: yesHaematologica, 2016
Plasmablastic lymphoma is a rare and aggressive diffuse large B-cell lymphoma commonly associated with Epstein-Barr virus co-infection that most often occurs in the context of human immunodeficiency virus infection.
Camille Laurent   +15 more
doaj   +1 more source

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu   +11 more
wiley   +1 more source

Epstein–Barr virus-associated lymphomas

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2017
Epstein–Barr virus (EBV), originally discovered through its association with Burkitt lymphoma, is now aetiologically linked to a remarkably wide range of lymphoproliferative lesions and malignant lymphomas of B-, T- and NK-cell origin. Some occur as rare
C. Shannon-Lowe, A. Rickinson, A. Bell
semanticscholar   +1 more source

Impact of a non-uniform charge distribution on virus assembly [PDF]

open access: yesPhys. Rev. E 96, 022401 (2017), 2017
Many spherical viruses encapsulate their genome in protein shells with icosahedral symmetry. This process is spontaneous and driven by electrostatic interactions between positive domains on the virus coat proteins and the negative genome. We model the effect of the icosahedral charge distribution from the protein shell instead of uniform using a mean ...
arxiv   +1 more source

Mixed Autoimmune Hemolytic Anemia: A Systematic Review of Epidemiology, Clinical Characteristics, Therapies, and Outcomes

open access: yesAmerican Journal of Hematology, EarlyView.
Mixed autoimmune hemolytic anemia (AIHA) is a rare condition characterized by the presence of both warm and cold autoantibodies, often leading to severe, treatment‐resistant hemolysis. In this systematic review of 81 patients across 35 studies, the median age was 45 years with a notable female predominance.
Jeremy W. Jacobs   +12 more
wiley   +1 more source

Resurrecting Epstein–Barr Virus

open access: yesPathogens, 2022
One of the Editor’s choice articles in 2021 published in Pathogens was an early assessment of the role of Epstein–Barr virus (EBV) reactivation in the pathogenesis of long-term symptoms associated with COVID-19 [...]
Roberto Paganelli
doaj   +1 more source

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