Results 71 to 80 of about 1,782,146 (327)

Alzheimer's Association clinical practice guideline for the Diagnostic Evaluation, Testing, Counseling, and Disclosure of Suspected Alzheimer's Disease and Related Disorders (DETeCD‐ADRD): Executive summary of recommendations for primary care

Alzheimer's &Dementia, EarlyView.
Abstract US clinical practice guidelines for the diagnostic evaluation of cognitive impairment due to Alzheimer's disease (AD) or AD and related dementias (ADRD) are decades old and aimed at specialists. This evidence‐based guideline was developed to empower all—including primary care—clinicians to implement a structured approach for evaluating a ...
Alireza Atri, Bradford C. Dickerson, Carolyn Clevenger, Jason Karlawish, David Knopman, Pei‐Jung Lin, Mary Norman, Chiadi Onyike, Mary Sano, Susan Scanland, Maria Carrillo   +10 more
wiley   +1 more source

Epstein‐Barr virus strain variation and cancer

Cancer Science, 2019
Epstein‐Barr virus (EBV) is a human tumor virus and is etiologically linked to various malignancies. Certain EBV‐associated diseases, such as Burkitt lymphomas and nasopharyngeal carcinomas, are endemic and exhibit biased geographic distribution ...
T. Kanda, Misako Yajima, K. Ikuta
semanticscholar   +1 more source

Identification of bioactive compounds and molecular targets of Fuke Huahuang formulation to treat vaginitis

Animal Models and Experimental Medicine, EarlyView.
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu, Jie Mo, Cheng Liang, Qingting Chen, Bin Yang, Jiaqi Liu   +5 more
wiley   +1 more source

Systemic Epstein-Barr-virus-positive T cell lymphoproliferative childhood disease in a 22-year-old Caucasian man: A case report and review of the literature

Journal of Medical Case Reports, 2011
Introduction Systemic Epstein-Barr-virus-positive T cell lymphoproliferative disease of childhood is an extremely rare disorder, characterized by clonal proliferation of Epstein-Barr-virus-infected T cells with an activated cytotoxic phenotype.
Meloni Giovanna, Sista Maria, Righi Simona, Mannu Claudia, Capria Saveria, Bacci Francesco, Gazzola Anna, Sabattini Elena, Agostinelli Claudio, Tabanelli Valentina, Pileri Stefano A, Piccaluga Pier   +11 more
doaj   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

Animal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang, Xianbin Zhao, Lili Tan, Pingxinyi Que, Tong Zhao, Wei Huang, Dejiao Yao, Songqi Tang   +7 more
wiley   +1 more source

Novel Therapeutics for Epstein–Barr Virus

Molecules, 2019
Epstein–Barr virus (EBV) is a human γ-herpesvirus that infects up to 95% of the adult population. Primary EBV infection usually occurs during childhood and is generally asymptomatic, though the virus can cause infectious mononucleosis in 35–50% of the ...
G. Andrei, E. Trompet, R. Snoeck
semanticscholar   +1 more source

Оptimization of Treatment EBV Infectious Mononucleosis in Children

Детские инфекции (Москва), 2015
The paper presents the results of observation of 103 children aged from 10 months to 15 years with EBV-associated infectious mononucleosis (IM), determined in 32% by acute primary Epstein-Barr virus infection (AEBVI) and in 68% of cases by reactivation ...
V. B. Kotlova, S. P. Kokoreva, A. V. Trushkina   +2 more
doaj   +1 more source

Effectiveness of Autologous Hematopoietic Stem Cell Transplantation versus Alemtuzumab and Ocrelizumab in Relapsing Multiple Sclerosis: A Single Center Cohort Study

Annals of Neurology, EarlyView.
Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro, Antonio Zito, Alessio Signori, Maria Pia Sormani, Eleonora Rigoni, Federica Pollidoro, Roberto Bergamaschi, Alice Mariottini, Omar Malik, Ashwini Nandoskar, Victoria Singh‐Curry, Varun Mehra, Majid Kazmi, Ian Gabriel, Eli Silber, Richard Nicholas, Antonio Scalfari   +16 more
wiley   +1 more source

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

Science Translational Medicine, 2019
EBNA1 inhibitors developed by fragment-based drug design block EBNA1 DNA binding and EBV-dependent tumor cell growth in vivo. No holds Barr-ed for cancer treatment Persistent latent infection with Epstein-Barr virus contributes to tumorigenesis in a ...
T. Messick, Garry R. Smith, S. Soldan, M. McDonnell, J. Deakyne, K. Malecka, Lois E Tolvinski, A. Pieter J. van den Heuvel, Baiwei Gu, J. Cassel, Donna H Tran, Benjamin R. Wassermann, Yan Zhang, Venkata Velvadapu, E. Zartler, P. Busson, A. Reitz, P. Lieberman   +17 more
semanticscholar   +1 more source

Evaluation of reactive Epstein-Barr virus (EBV) in Iranian patient with different subtypes of multiple sclerosis (MS)

Brazilian Journal of Infectious Diseases, 2013
OBJECTIVES: Epstein-Barr virus has been recently associated with the onset of multiple sclerosis, yet understanding how it elicits autoimmunity remains elusive.
Nourollah Ramroodi, Abbas Ali Niazi, Nima Sanadgol, Zohre Ganjali, Vida Sarabandi   +4 more
doaj   +2 more sources