Results 61 to 70 of about 71,544 (304)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

* and CH*, Charge Pressure, and Equivalence Ratio for Gasoline

open access: yes, 2018
This work presents the results of an intensity-based fuel-air calibration for a range of charge pressures for gasoline fuel. The radical intensity ratio of diatomic carbon (C2∗) to methylidene (CH∗) was acquired through line-of-sight chemiluminescence ...
Reyes, Jonathan   +5 more
core   +1 more source

Numerical study of inflow equivalence ratio inhomogeneity on oblique detonation formation in hydrogen-air mixtures [PDF]

open access: yes, 2017
In this study, numerical simulations using Euler equations with detailed chemistry are performed to investigate the effect of fuel-air composition inhomogeneity on the oblique detonation wave (ODW) initiation in hydrogen-air mixtures. This study aims for
Fang YS(方宜申)   +4 more
core   +3 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Methane-air equivalence ratio effect on premixed turbulent low swirl stabilized flame

open access: yes, 2014
This work presents a numerical simulation of premixed methane-air low swirl stabilized flame, the geometry describes a low swirl burner kind. Reynolds average Navier-Stokes standard κ-ε model for turbulence coupling to partially premixed model for ...
Belmrabet, T.   +2 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Lean partially premixed turbulent flame equivalence ratio measurements using laser-induced breakdown spectroscopy [PDF]

open access: yes, 2018
The creation of a more stable flame along with the extension of flammability limits under lean mixture combustion was the main motivation to develop a new burner design, which has been investigated in this research.
Hamza, Mahmoud   +14 more
core   +1 more source

Effects of each operating condition on the underwater shock waves driven by imploding detonation and microorganism treatment experiments

open access: yesJournal of Thermal Science and Technology, 2015
In recent years, microorganisms contained in ship ballast water have been identified as vectors for the destruction of marine ecosystems. To control such microorganisms, various techniques are being developed and tested.
Yohichi UDAGAWA, Minoru SUZUKI
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Research on the Ignition-Chamber GDI Engine Combustion System

open access: yesJournal of Thermal Science and Technology, 2009
The ignition-chamber GDI engine combustion system and its fuel injection strategy were presented and studied by multi-dimensional fluid dynamic (CFD) code and experiment.
Lei FU   +3 more
doaj   +1 more source

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