Results 111 to 120 of about 22,519 (238)

Differential distribution of ERα and ERβ mRNA in intrauterine tissues of the pregnant rhesus monkey

, 2000
Two estrogen receptor (ER) isoforms, ERα and ERβ, have been described. However, no information is available in any species regarding the comparison of ERα and ERβ levels in pregnant intrauterine tissues.
Wen Xuan Wu, Gordon C. S. Smith, Xiao Hong Ma, Peter W. Nathanielsz   +3 more
core   +1 more source

Health Insurance Coverage and Rural–Urban Differences in Maternal Health Care Among Postpartum Women—National Health Interview Survey

Birth, EarlyView.
Are there rural–urban differences in maternal health and care among postpartum women, and do those differences vary by insurance coverage? This study used the 2013–2018 National Health Interview Surveys of 2,664 non‐pregnant female respondents ages 18–49 with an infant under age one.
Julia D. Interrante, Alyssa H. Fritz, Sara C. Handley, Clara E. Busse, Katy B. Kozhimannil   +4 more
wiley   +1 more source

Perinatal testosterone exposure potentiates vascular dysfunction by ERβ suppression in endothelial progenitor cells.

PLoS ONE, 2017
Recent clinical cohort study shows that testosterone therapy increases cardiovascular diseases in men with low testosterone levels, excessive circulating androgen levels may play a detrimental role in the vascular system, while the potential mechanism ...
Weiguo Xie, Mingming Ren, Ling Li, Yin Zhu, Zhigang Chu, Zhigang Zhu, Qiongfang Ruan, Wenting Lou, Haimou Zhang, Zhen Han, Xiaodong Huang, Wei Xiang, Tao Wang, Paul Yao   +13 more
doaj   +1 more source

Predictors of Shoulder Dystocia: A Retrospective Case–Control Study

Birth, EarlyView.
ABSTRACT Introduction Shoulder dystocia (SD) is rare, but it has serious consequences. Antepartum risk stratification for SD has demonstrated variability across populations, reflecting differences in assessment methodologies. Methods We conducted a retrospective analysis using a prospectively audited electronic database from a single center.
Nisarat Phithakwatchara, Katika Nawapun, Suparat Jaingam, Julaporn Pooliam, Tuangsit Wataganara   +4 more
wiley   +1 more source

Estrogen dependent activation function of ERβ is essential for the sexual behavior of mouse females

, 2012
International audienceWe previously generated and characterized a genuine estrogen receptor (ER) β-null mouse line (named ERβ ST L−/L− ) and showed that ERβ ST L−/L− mice were sterile, due to an ovulation impairment in females and to an unknown reason in
Petit-Demouliere, Benoit, Antal, Maria Cristina, Meziane, Hamid, Chambon, Pierre, Krust, Andrée   +4 more
core   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Facilitation of mucosal healing by estrogen receptor β in ulcerative colitis through suppression of branched-chain amino acid transport and subsequent triggering of autophagy in colonic epithelial cells

Acta Pharmaceutica Sinica B
Colonic mucosal healing is the ultimate goal of ulcerative colitis (UC) treatment, but it remains difficult to realize. Given the higher incidence of UC in males and the beneficial effect of estrogen on UC, we conducted this study to examine the ...
Yilei Guo, Yanrong Zhu, Jing Zhang, Yue He, Mianjiang Zhao, Haochang Lin, Zhifeng Wei, Yufeng Xia, Yue Dai   +8 more
doaj   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

Alignment of lamprey ER with human ERα and human ERβ.

, 2013
α-helices and β-strands from the crystal structures of ERα and ERβ are shaded in each sequence and notated below the alignment. Residues in human ERα involved in binding of estradiol are shown in green.
Charlie Chandsawangbhuwana (31494), Michael E. Baker (27422), David J. Chang (372055)   +2 more
core   +1 more source

Comprehensive Genomic Profiling Beyond Driver Testing in Non‐Squamous Non‐Small Cell Lung Cancer With Known Drivers

Cancer Science, EarlyView.
Figure 6 Comprehensive genomic profiling identified additional actionable alterations in a substantial proportion of patients with non‐squamous NSCLC despite previously identified driver alterations, with some findings leading to subsequent matched targeted therapies.
Yoshihiro Masui, Tatsuya Yoshida, Yoh Yamaguchi, Jun Miyakoshi, Ryoko Inaba Higashiyama, Akiko Tateishi, Yuki Shinno, Yuji Matsumoto, Yusuke Okuma, Tomonori Mizutani, Hidehito Horinouchi, Kouya Shiraishi, Takashi Kohno, Takafumi Koyama, Noboru Yamamoto, Yasushi Goto   +15 more
wiley   +1 more source