Results 101 to 110 of about 29,801 (212)

Elevated ERβ expression driven by low ASB8-mediated ubiquitination in lung adenocarcinoma promotes lymph node metastasis via tumor-associated neutrophils

Cell Death and Disease
This study investigated the role of estrogen receptor beta (ERβ) in the lymph node metastasis of lung adenocarcinoma (LUAD), focusing on its interaction with tumor-associated neutrophils (TANs) and its regulation of lymphangiogenesis.
Yangwei Wang, Shiwen He, Mingxin Diao, Rong Zhao, Jinghua Ren, Peiyuan Mei, Shihao Wu, Sheng Fan, Yongde Liao   +8 more
doaj   +1 more source

Conversion of a selective ERβ agonist into a potent antagonist via long-chain derivatization

Results in Chemistry
Estrogen receptor β (ERβ) is overexpressed in certain cancers, including triple-negative breast cancer (TNBC), and has context-dependent roles that can promote or suppress tumor progression. To explore its therapeutic potential, we designed WC10, a novel
Takuji Shoda, Moena Tsuda, Naoya Hirata, Hideshi Inoue, Yasunari Kanda, Yosuke Demizu   +5 more
doaj   +1 more source

Quantum Fermion Hair

, 1992
It is shown that the Dirac operator in the background of a magnetic %Reissner-Nordstr\"om black hole and a Euclidean vortex possesses normalizable zero modes in theories containing superconducting cosmic strings.
D. R. Brill, E. Weinberg, E. Witten, F. Dowker, Jeffrey A. Harvey, L. Krauss, M. Bowick, R. Jackiw, Ruth Gregory, S. Coleman, S. Coleman, S. Coleman   +11 more
core   +1 more source

Navigating Ethical Review Processes in Conflict‐Affected, Authoritarian Contexts: A Case Study of Myanmar's Interim Ethics Review Board (IERB)

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This article examines the formation and operation of Myanmar's Interim Ethics Review Board (IERB), which was established in November 2023 by displaced academics involved in the Civil Disobedience Movement against the 2021 military coup. Operating within a highly repressive, conflict‐ridden environment, the IERB exemplifies a locally‐led and ...
Phyu Phyu Thin Zaw, Su Su Maw, Nyein Chan, The Spring IERB Team   +3 more
wiley   +1 more source

Comparative study of estrogen receptor α, β mRNA expressions of endometriosis and normal endometrium in women and analysis of potential synthetic anti-estrogens in silico

Journal of Biological Research, 2018
Endometriosis is a multifactorial disease in which genetic and environmental factors interact causing its pathogenesis. The aim of this study was to investigate the expression pattern of estrogen receptor α (ERα) and β (ERβ) in endometriosis patients ...
Eldafira Eldafira, Abinawanto Abinawanto, Luthfiralda Sjahfirdi, Asmarinah Asmarinah, Purnomo Soeharso, Muharam Muharam, Vivitri D. Prasasty, Dwi A. Pujianto   +7 more
doaj   +1 more source

Health Insurance Coverage and Rural–Urban Differences in Maternal Health Care Among Postpartum Women—National Health Interview Survey

Birth, EarlyView.
Are there rural–urban differences in maternal health and care among postpartum women, and do those differences vary by insurance coverage? This study used the 2013–2018 National Health Interview Surveys of 2,664 non‐pregnant female respondents ages 18–49 with an infant under age one.
Julia D. Interrante, Alyssa H. Fritz, Sara C. Handley, Clara E. Busse, Katy B. Kozhimannil   +4 more
wiley   +1 more source

Not that different after all: Pro‐environmental social norms predict pro‐environmental behaviour (also) among those believing in conspiracy theories

British Journal of Psychology, EarlyView.
Abstract Social norms are powerful predictors of pro‐environmental behaviour. At the same time, conspiracy beliefs are prevalent that can reduce individuals' efforts to act pro‐environmentally and might impede the influence of social norms. Across three cross‐sectional studies in three countries (Germany, UK, US; total N = 1037), we investigated the ...
Kevin Winter, Lotte Pummerer, Kai Sassenberg   +2 more
wiley   +1 more source

Trichoplax, the simplest known animal, contains an estrogen-related receptor: Implications for the evolution of vertebrate and invertebrate estrogen receptors [PDF]

, 2008
Although, as their names imply, vertebrate and invertebrate estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to each other are not fully understood.
Michael E. Baker
core   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Motif analysis of amphioxus, lamprey and invertebrate estrogen receptors and amphioxus and human estrogen-related receptors: Towards a better understanding of estrogen receptor evolution [PDF]

, 2008
*Background.* The origins of steroid-dependent regulation of the vertebrate estrogen receptor (ER) are poorly understood. Genes with statistically significant sequence similarity to vertebrate ERs have been found in lamprey, a basal vertebrate, and ...
Charlie Chandsawangbhuwana, Michael E. Baker   +1 more
core   +2 more sources