Results 151 to 160 of about 17,657 (203)

Estrogen signaling processes in fibroblasts: a scoping review. [PDF]

Front Endocrinol (Lausanne)
Roy N, Casarini L, Smetanina D, Al Awar S, Zaręba K.   +4 more
europepmc   +1 more source

Genome Sequencing in 19 Families With Bladder Exstrophy and Epispadias Complex Indicates Involvement of the ADGR ‐Gene Family

American Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1286-1305, June 2026.
ABSTRACT Bladder exstrophy and epispadias complex (BEEC) is one of the most severe congenital malformations of the urogenital tract, significantly impacting continence, sexual function, and renal function. To date, the only recurrent genetic aberration identified is the 22q.11.2 microduplication, but several candidate regions and genes including ...
Agneta Nordenskjöld, Samara Alm, Jesper Eisfeldt, Jia Cao, Magnus Anderberg, Gillian Barker, Hans Matsson, Gundela Holmdahl, Anna Lindstrand, Kristina Lagerstedt‐Robinson   +9 more
wiley   +1 more source

Tumor-associated macrophages suppress estrogen receptor-β expression in triple-negative breast cancer through the PI3K/AKT pathway. [PDF]

Exp Ther Med
Zhang Q, Guo D, Xu G, Xie R, Deng Y, Fu P, Wan J.   +6 more
europepmc   +1 more source

Sex differences in brain glucose metabolism and Alzheimer's disease risk and progression

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Sex differences are increasingly recognized as central to the biology of Alzheimer's disease (AD), yet the mechanisms through which they shape brain metabolism and disease vulnerability remain incompletely understood. Brain glucose hypometabolism is a core hallmark of AD and emerges decades before clinical decline, but accumulating evidence ...
Marjan Ramezan, Aphrodite Demetriou, Sara Nicole Burke, Ivan Nalvarte, Andrew C. Shin   +4 more
wiley   +1 more source

Porphyromonas gingivalis disrupts hippocampal circadian clock via PI3K/AKT pathway, exacerbating Alzheimer‐like pathology

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
A graphical abstract is provided to visually summarize the key findings of this study. Abstract INTRODUCTION Periodontal pathogen Porphyromonas gingivalis is epidemiologically linked to Alzheimer's disease (AD), yet how oral infection disrupts the central circadian clock to drive hippocampal neurodegeneration remains unknown.
Chunmei Huang, Qin Cai, Zeru Feng, Chenze Zhang, Zhiqiang Luo, Xingqun Cheng, Hongkun Wu   +6 more
wiley   +1 more source

Exploring Risk Factors and Sex Differences in Colorectal Cancer: Insights from Current Evidence. [PDF]

Cells
Cittadini C, Iessi E, Vona R, Matarrese P.   +3 more
europepmc   +1 more source

Vulnerability of anterior medial temporal lobe subregions to early tau‐related neurodegeneration in Alzheimer's disease: Converging evidence from tau‐PET and plasma p‐tau217

Alzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract INTRODUCTION The anterior medial temporal lobe (MTL), including the entorhinal cortex (ERC) and Brodmann area 35 (BA35), is among the earliest cortical sites of tau pathology in Alzheimer's disease (AD), yet conventional image segmentation methods poorly capture these regions.
Nidhi S. Mundada, Niyousha Sadeghpour, Emily McGrew, Hannah L. Tucker, Ilya M Nasrallah, Sandhitsu R. Das, David A. Wolk, Paul A. Yushkevich, Christopher A Brown, Laura E. M. Wisse   +9 more
wiley   +1 more source

Prenatal bisphenol A exposure reprograms SF1-lactylation pathways to promote endometriosis susceptibility. [PDF]

iScience
Liu X, Fu Y, Huang L, Li D, Yao P, Zeng L.   +5 more
europepmc   +1 more source

Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer's Disease Using PET and Plasma Biomarkers

Annals of Neurology, Volume 99, Issue 6, Page 1438-1451, June 2026.
Objective This study aimed to compare positron emission tomography (PET) and plasma‐based temporal modeling of amyloid and tau biomarkers in Alzheimer's disease. Methods Longitudinal amyloid PET (n = 1,097, mean age ± SD = 72.5 ± 7.38 year, 51.4% male), 18F‐flortaucipir tau‐PET (n = 230, 74.3 ± 7.18 year, 52.2% female), and Fujirebio Lumipulse plasma p‐
Christopher A. Brown, Katheryn A.Q. Cousins, Magdalena Korecka, Emily McGrew, Alice Chen‐Plotkin, John A. Detre, Corey T. McMillan, Edward B. Lee, Sandhitsu R. Das, Dawn Mechanic‐Hamilton, Paul A. Yushkevich, Ilya M. Nasrallah, Leslie M. Shaw, for the Alzheimer's Disease Neuroimaging Initiative, David A. Wolk   +14 more
wiley   +1 more source

Systemic testosterone induces structural, immunological, and sex steroid receptor changes in human XX skin. [PDF]

Sci Rep
Dabrosin N, Abrahamsson A, Kratz G.
europepmc   +1 more source