Results 161 to 170 of about 17,657 (203)

Unmet Needs in Mental Health: A Cross‐Sectional Study on Contact Coverage Gaps and Access to Care for Depression and Anxiety Among Adults in Kailali, Nepal

Brain and Behavior, Volume 16, Issue 6, June 2026.
A substantial mental health contact coverage gap (71.7%) exists in rural Nepal, with fewer than one‐third of individuals with depression or anxiety accessing formal care. Financial barriers, self‐reliance, alternative care preferences, and limited awareness were the leading hurdles to treatment seeking.
Gayatri Khanal, Y. Selvamani, Prabhat Sapkota   +2 more
wiley   +1 more source

Sex-informed estrogen receptor modulation in schizophrenia: a male-focused ERβ/GPER1 framework for cognitive and negative symptoms. [PDF]

Front Psychiatry
Carlson J.
europepmc   +1 more source

Toosendanin Alleviates Cerebral Ischemia/Reperfusion Injury via Inhibiting Neural Ferroptosis Through Lipid Metabolic Reprogramming in MCAO Mice

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Post‐stroke administration of TSN significantly reduced infarct volume, neuroinflammation, and improved functional recovery of MCAO mice. TSN alleviated neural oxidative stress, lipid peroxidation, and ferroptosis in MCAO mice. TSN modulated the infiltration of immune cells in MCAO mice in vivo and T cell differentiation in vitro.
Xinyun Li, Zhiyong Zhao, Jingting Zhao, Xiangming Ye, Zhenfei Xiong, Jiejin Zhao   +5 more
wiley   +1 more source

Estrogen deficiency induces pelvic floor muscle atrophy via ERα/GLUT4 pathway. [PDF]

PLoS One
Huang X, Zhou M, Wang Y, Chen M, Xiao Y, Li L, Zhu F, Chen L, Tian X, Wu S, Li B, Hong L.   +11 more
europepmc   +1 more source

Predicting Depression Risk in Physically Inactive Older Adults Using Dietary Antioxidants and Machine Learning: A SHAP‐Interpretable Analysis of NHANES

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
This study applied machine learning and SHAP analysis to identify key dietary antioxidants that predict depression risk in physically inactive older adults, highlighting the roles of vitamin E, luteolin, flavonoids, copper, magnesium, and iron. ABSTRACT Background Physically inactive older adults represent a high‐risk group for depression.
Yuwen ShangGuan, Kunpeng Wu, Dong Li, Young‐Je Sim, Chuang Zhang, Zhenhao Lin, Litao Yan   +6 more
wiley   +1 more source

The endocrine disruptor chlorpyrifos alters hypothalamic Npy and Agrp expression via ERβ-dependent regulation <i>in vitro</i> and <i>in vivo</i>. [PDF]

Front Endocrinol (Lausanne)
Pastorino M, Desiderio A, Perrella E, Campitelli M, Nigro C, Peluso T, De Felice M, Ambrosino C, Beguinot F, Miele C, Raciti GA.   +10 more
europepmc   +1 more source

Cardiovascular β‐Adrenergic Receptor Distribution and Function: Influence of Species, Sex, Age, and Tissue

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
Estrogen modulates β‐AR signaling in a context‐dependent manner influenced by species, sex, age, tissue, and vascular health, highlighting challenges in translating findings from experimental models to human cardiovascular physiology. ABSTRACT Cardiovascular diseases remain the leading global cause of morbidity and mortality, with notable sex‐specific ...
Basant Elsaid, Irakli Kopaliani, Birgit Zatschler, Ansam Seif, Stephan Speier, Andreas Deussen   +5 more
wiley   +1 more source

Molecular mechanisms and clinical impacts of sex differences in urologic cancers. [PDF]

Discov Oncol
Fu P, Wen D, Shuai G, Wang Y, Yu S, Xie Y, Xue P, Liang Z, Zou J, Zou X.   +9 more
europepmc   +1 more source

Disentangling geography teacher educators' collective spaces of agency

The Curriculum Journal, Volume 37, Issue 2, Page 247-262, June 2026.
Abstract Societal trends such as increased accountability, teacher shortages, and flexibility in learning paths affect the work of teacher educators. This study explores the collective agency of Dutch geography teacher educators as they enact the subject pedagogy curriculum within this rapidly changing context.
Eefje Smit, Tine Béneker, Hanneke Tuithof   +2 more
wiley   +1 more source

The Role of Estrogen Signaling Pathway and Targeted Therapy Exploration in Urological Tumors. [PDF]

Int J Biol Sci
Ma C, Yang L, Li W, Shangguan W, Huang W, Li Z, Sun B, Yang X, Xu H, Li Z, Peng P, Wang Z, Wu P, Cheng B.   +13 more
europepmc   +1 more source