Results 181 to 190 of about 17,657 (203)
CEBP and ZEB2 alterations define three distinct subtypes of B‐cell acute lymphoblastic leukemia
Abstract B‐cell acute lymphoblastic leukemia (B‐ALL) is a heterogeneous malignancy driven by diverse genetic alterations. Among these, CEBP family genes and ZEB2 are recurrently involved, yet the spectrum of genomic mechanisms and their clinical impact remain incompletely defined.
Rathana Kim +29 more
wiley +1 more source
2-Hydroxyestradiol regulates extracellular matrix deposition through estrogen receptor beta activation in airway smooth muscle cells. [PDF]
Kumar A +10 more
europepmc +1 more source
Abstract Objective This study determines whether a machine‐learning model integrating sonographic biometry with maternal clinical parameters improves prediction of large‐for‐gestational‐age (LGA) compared with Hadlock's EFW formula. Methods We conducted a retrospective cohort study including all singleton live births at ≥32 gestational weeks at a ...
Ohad Houri +7 more
wiley +1 more source
Overview of the effects of Pax1‐SAR deletion on gene expression, IVD degeneration, and resultant scoliotic‐like curvature between sexes. Proposed mechanism of sex‐dependent changes in gene expression in females (right) and males (left), resulting in sex‐dependent disc degeneration and scoliotic phenotypes.
Edward C. Moody +4 more
wiley +1 more source
Repurposing nuclear receptors for ligand-responsive liquid condensate formation and gene regulation. [PDF]
Rihtar E +4 more
europepmc +1 more source
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jan Ulrich Jansen +9 more
wiley +1 more source
Ribifolones A-H, New Macrocyclic Diterpenes from <i>Jatropha ribifolia</i>, Their Cytotoxic Activity and Insights Supported by Network Pharmacology and Molecular Modeling. [PDF]
de Souza TA +12 more
europepmc +1 more source
A whole ecosystem perspective of hypoxia and its drivers in a large temperate freshwater estuary
Abstract Hypoxic conditions have become increasingly common during the summer in the bottom waters of seasonally stratified inland and coastal waters. While ultimately driven by carbon and nutrient loading from the watershed and subsequent excessive algal production, the formation and duration of hypoxia are largely controlled by coupled physical ...
Shelby Brunner +4 more
wiley +1 more source
Role of ERβ in Triple-Negative Breast Cancer Associated with p53 and Androgen Receptor. [PDF]
Ito K +9 more
europepmc +1 more source

