Results 181 to 190 of about 22,519 (238)

Efficacy and Safety of Elagolix Versus Dienogest for Treatment of Moderate‐to‐Severe Endometriosis Pain: A Phase III, Multicentric, Double‐Blind, Active‐Controlled, Non‐Inferiority Study

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 2025-2034, October 2026.
ABSTRACT Objective To compare the efficacy, safety and tolerability of elagolix with dienogest in women with moderate‐to‐severe endometriosis‐associated pain. Design A multicentre, double‐blind, double‐dummy, randomised, parallel‐group, active‐controlled, non‐inferiority phase III study. Setting Nineteen clinical centres across India.
Sneha Bhoir, Jaldhara Patel, Tushar Palve, Mrinal Kanti Dash, Sweety Saigal, Gourisankar Kamilya, Shalini Srivastava, Kartikbhai Savalia, Tanusree Gupta, Deepa Choudhary, Manohar Rangaswamy, Vidya V Bhatt, Neena Gupta, Malathi Ponnuru, Parul Shah, Apurva Shetty, Shruti Saha, Reshma Quadros, Sucheta Pandit, Dipak Patil, Piyush Patel, Pravin Ghadge, Lalit Lakhwani, Suyog Mehta, Sadhana Joglekar   +24 more
wiley   +1 more source

Progress of estrogen receptor and splice variants in ovarian carcinoma. [PDF]

J Ovarian Res
Mo T, Hong Z, Mo Y, Tian J, Chen J.
europepmc   +1 more source

Inducible tomato defences persist in detached leaves, despite differential plant variety and gene‐dependent expression

Ecological Entomology, Volume 51, Issue 5, Page 866-874, October 2026.
Short‐ and long‐term expression of PPO‐D, PI‐IIc and PR‐1a were assessed in intact plants and detached tomato leaves of two varieties infested with Tetranhycus urticae. Tomato defences were induced in both intact and detached leaves, but the induction levels varied with plant variety and gene assessed.
Mariya Kozak, Diogo P. Godinho, Eren Yayla, Juan Adánez, Inês Fragata, Sara Magalhães, Leonor R. Rodrigues   +6 more
wiley   +1 more source

Bazedoxifene and Beyond: Identifying This SERM's Targets and Deciphering Its Molecular Mechanisms. [PDF]

Adv Pharmacol Pharm Sci
Bherer J, Clemenceau A, Diorio C, Durocher F.   +3 more
europepmc   +1 more source

IMPLICATION IN YOUNG ADULT NOVELS ABOUT THE GDR: HISTORICAL FICTION FOR A DEMOCRATIC FUTURE

German Life and Letters, Volume 79, Issue 4, Page 472-494, October 2026.
ABSTRACT This article examines the pedagogical potential of young adult literature about East Germany to help readers reflect on the legacies of authoritarian rule and questions of responsibility, accountability and agency. Drawing on Michael Rothberg's concept of the implicated subject, I argue that young adult literature exploring implication offers ...
Kristin Rebien
wiley   +1 more source

The multisystem impact of perimenopausal hormonal fluctuations on chronic disease risk. [PDF]

Front Endocrinol (Lausanne)
Luo L, Li L, Wang X, Bai W.
europepmc   +1 more source

Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1

Background:  Estrogen receptor beta (ERβ, Esr2) plays a pivotal role in folliculogenesis and ovulation, yet its exact mechanism of action is mainly uncharacterized.Results: We here performed ChIP-sequencing of mouse ovaries followed by complementary RNA ...
Deng, Qiaolin, Birgersson, Madeleine,, Lindquist, Linnea, Stepanauskaite, Lina,, Williams, Cecilia,, Luo, Qing, Indukuri, Rajitha,, Archer, Amena,   +7 more
core  

Circadian Deregulation in Multiple Myeloma: BMAL1/CLOCK Expression Patterns and Diagnostic Performance

International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 1123-1132, October 2026.
ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak, Mustafa Ertan Ay, Anıl Tombak, Kenan Çevik, Özlem İzci Ay, Tuba Kabasakal, Mehmet Emin Erdal   +6 more
wiley   +1 more source

Estradiol Ameliorates Postmenopausal Bladder Dysfunction by Restoring Mitophagy via the miRNA-200/KLF4/mTOR Signaling Pathway. [PDF]

Int J Mol Sci
Chueh KS, Lu JH, Mao JW, Wu BN, Long CY, Miao ZF, Juan TJ, Lin RJ, Chuang SM, Shen MC, Sun TW, Lu MC, Juan YS.   +12 more
europepmc   +1 more source

Endocranial anatomy of the earliest Cretaceous European neosuchian crocodyliform Pholidosaurus purbeckensis provides new evidence for the ecological evolution of Pholidosauridae

Journal of Anatomy, Volume 249, Issue 4, Page 787-802, October 2026.
We present new insights into the internal cranial anatomy of the neosuchian crocodyliform Pholidosaurus purbeckensis, based on CT‐scan data of material from the lowermost Cretaceous Purbeck Limestone Group, southern UK. From the study of the endocast, we obtained new information on the phylogeny and the ecological evolution of the Family ...
Leonardo Barbini, Paul M. J. Burke, Ilaria Caddeo, Marco Romano, Philip D. Mannion   +4 more
wiley   +1 more source