Results 111 to 120 of about 3,252 (178)
Beyond the Secretory Pathway: New Insights Into Protein Release
Traffic, Volume 26, Issue 10-12, October/December 2025.While proteins bearing N‐terminal signal or leader sequences are secreted via the ER‐Golgi‐plasma membrane axis of the conventional secretion pathway, many cytosolic proteins lacking signaling sequence can be secreted via poorly defined mechanisms termed Unconventional Protein Secretion (UcPS).Ruey‐Hwa Chen, Antonio J. Costa‐Filho, Jayanta Debnath, Thierry Galli, Liang Ge, Deborah Goberdhan, Wei Guo, Kangmin He, Ralf Jacob, Tiebang Kang, Min Goo Lee, Lian Li, Fabio Lolicato, Jun Lu, Vivek Malhotra, Walter Nickel, Vassiliki Nikoletopoulou, Stacey K. Ogden, Georgia Maria Sagia, Feng Shao, Anbing Shi, Clotilde Thery, Christel Vérollet, Julien Villeneuve, Frederik Verweij, Yanzhuang Wang, Juan Wang, Shenjie Wu, Yihong Ye, Hang Yin, Li Yu, Min Zhang, Ying Zhang, Xin Zhou, Chiara Zurzolo +34 morewiley +1 more sourceNeurodegenerative Diseases and Autophagy [PDF]
, 2018 Most neurodegenerative diseases are characterized by the accumulation of aggregated proteins within neurons. These aggregate-prone proteins cause toxicity, a phenomenon that is further exacerbated when there is defective protein clearance.Aflaki, Aflaki, Aguado, Aguib, Akizu, Al-Saif, Alves, Ando, Ando, Andrew, Argov, Argov, Arrasate, Ashkenazi, Axe, Ballabio, Belzil, Benjamin, Bento, Berger, Bernhardt, Biazik, Bitoun, Bjorkoy, Blanz, Blommaart, Boland, Bouhouche, Bryceson, Butzlaff, Byrne, Caccamo, Caccamo, Caccamo, Cadwell, Castillo, Castillo, Cataldo, Cataldo, Chan, Chang, Chen, Chen, Chen, Cheroni, Chesser, Chung, Cirulli, Citron, Coffey, Colacurcio, Conner, Corcelle-Termeau, Cortes, Cortes, Criado, Cullup, Cunha-Santos, Cunningham, Daud, Davies, de Duve, DeBosch, Decressac, Dehay, DeJesus-Hernandez, del Campo, Deng, Deretic, DeSelm, Di Bartolomeo, Dierks, Dionisi Vici, Dooley, Dowdle, Dressel, Du, Duran, Durcan, Durcan, Durieux, Egan, Eisenberg, Eisenberg, Emanuele, Endo, Fader, Fang, Farg, Farrer, Fecto, Fernandes, Filimonenko, Fink, Fleming, Fraldi, Freischmidt, Fujita, Fullgrabe, Furuta, Gal, Ganley, Ganley, Gatchel, Gautam, Ge, Ge, Ghavidel, Goedert, Goedert, Gomez-Sanchez, Goode, Graef, Haack, Hadano, Hamacher-Brady, Hamasaki, Hansen, Hara, Harms, Harris, Hawkins-Salsbury, Hayashi-Nishino, Heitman, Heo, Hirst, Hong, Hosokawa, Hsieh, Huang, Huett, Huotari, Ichimura, Itakura, Jaeger, Jahn, Jang, Jang, Jiang, Jung, Kamiya, Kane, Kaneb, Karanasios, Kaushik, Kazlauskaite, Kett, Khaminets, Khaminets, Khurana, Kim, Kim, Kim, Kim, Kimura, Kimura, Kirkin, Kitada, Knaevelsrud, Knorr, Komatsu, Komatsu, Komatsu, Komatsu, Kondapalli, Koyano, Kraft, Krasniak, Kruger, Kuma, Kyttala, Labuzek, Lacovich, Lamb, Laplante, Lazarou, Lee, Lee, Lee, Lee, Lee, Levine, Li, Li, Liang, Lin, Liu, Liu, Liu, Lloyd-Evans, Lloyd-Evans, Longatti, Lonskaya, Lonskaya, Lopez, Lopez de Maturana, Lu, Lu, Lunemann, Luty, Luzio, Lv, Ma, Ma, Magalhaes, Majid, Mancias, Mandell, Manzanillo, Marshall, Martinez-Vicente, Maruyama, Matikainen-Ankney, Mawuenyega, Mayer, Mazzulli, Mazzulli, McWilliams, Mealer, Medina, Melser, Menzies, Menzies, Menzies, Michaud, Millecamps, Minassian, Mizuno, Mizushima, Mizushima, Mizushima, Mochida, Moore, Moreau, Moreau, Morimoto, Murphy, Murray, Myeku, Nakatogawa, Narang, Narendra, Nascimento-Ferreira, Nazio, Newman, Nguyen, Nilsson, Nishiyama, Nixon, Nixon, Noda, Onofre, Ordureau, Orsi, Oz-Levi, Ozcelik, Pacheco, Palikaras, Pankiv, Papinski, Park, Park, Pavel, Perez, Pickford, Pickrell, Pilli, Piras, Platt, Potter, Poupetova, Proikas-Cezanne, Pryor, Puls, Puri, Pyo, Ramesh Babu, Randow, Ravikumar, Ravikumar, Ravikumar, Ravikumar, Ravikumar, Razi, Reinwald, Renvoise, Richards, Rockenstein, Roczniak-Ferguson, Rodriguez-Navarro, Rogov, Rohn, Roosen, Rose, Rubinsztein, Rubinsztein, Rui, Russell, Rusten, Saftig, Sahu, Saitsu, Sanchez-Martinez, Sandoval, Sanjuan, Sano, Sardiello, Sarkar, Sarkar, Sato, Schaeffer, Schreiber, Schroder, Sellier, Seok, Serrano-Puebla, Settembre, Settembre, Settembre, Shaid, Shen, Shibata, Shibutani, Siddiqi, Siddiqui, Simonsen, Singh, Small, Son, Sorbara, Sou, Spampanato, Spilman, Staats, Stadel, Sun, Sundaramoorthy, Svenning, Tan, Tanaka, Tang, Tanji, Teyssou, Thurston, Tian, Tian, Tiede, Tien, Tsuboyama, Tsunemi, Tumbarello, Ugolino, Ulgherait, Ushio, Valente, Vantaggiato, Varga, Velikkakath, Vidoni, Vingtdeux, Vollrath, Wang, Wang, Wang, Watabe, Webb, Webster, Weedon, Wei, West, Wild, Williams, Williams, Winklhofer, Winslow, Wolfe, Wong, Wraith, Wu, Xi, Yamamoto, Yazdankhah, Yla-Anttila, Yoshii, Yu, Yu, Yu, Yuan, Yue, Zare-Shahabadi, Zavodszky, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zheng, Zhou, Zhou, Zuchner +401 morecore +1 more sourceA family of membrane-shaping proteins at ER subdomains regulates pre-peroxisomal vesicle biogenesis [PDF]
, 2016 Saccharomyces cerevisiae contains three conserved reticulon and reticulon-like proteins that help maintain ER structure by stabilizing high membrane curvature in ER tubules and the edges of ER sheets.Agrawal, Agrawal, Agrawal, Amit S. Joshi, Anwar, Bartlett, Bellu, Campbell, Chen, Chen, Choudhary, David, Dawson, Dimitrov, English, Goyal, Haan, Hoepfner, Hu, Hu, Junjie Hu, Khaminets, Kim, Knoops, Lam, Longtine, Mast, Mochida, Motley, Rucktäschel, Santos-Rosa, Shemesh, Shibata, Shibata, Shindiapina, Tim P. Levine, Tolley, Ueda, van der Zand, Van Veldhoven, Vedrenne, Vineet Choudhary, Vizeacoumar, Vizeacoumar, Voeltz, Voss, Waterman-Storer, West, Westrate, William A. Prinz, Williams, Witkin, Xiaofang Huang, Yan, Yonekawa +54 morecore +2 more sourcesFat storage-inducing transmembrane (FIT or FITM) proteins are related to lipid phosphatase/phosphotransferase enzymes [PDF]
, 2018 Fat storage-inducing transmembrane (FIT or FITM) proteins have been implicated in the partitioning of triacylglycerol to lipid droplets and the budding of lipid droplets from the ER.Carman, GM, Choudhary, V, Han, G-S, Hayes, M, Levine, T, Loewen, CJ, Ojha, N, Prinz, WA, Shin, JJ +8 morecore +1 more sourceTwo FAM134B isoforms differentially regulate ER dynamics during myogenesis
The EMBO JournalEndoplasmic reticulum (ER) plasticity and ER-phagy are intertwined processes essential for maintaining ER dynamics. We investigated the interplay between two isoforms of the ER-phagy receptor FAM134B in regulating ER remodeling in differentiating ...Viviana Buonomo, Kateryna Lohachova, Alessio Reggio, Sara Cano-Franco, Michele Cillo, Lucia Santorelli, Rossella Venditti, Elena Polishchuk, Ivana Peluso, Lorene Brunello, Carmine Cirillo, Sara Petrosino, Malan Silva, Rossella De Cegli, Sabrina Di Bartolomeo, Cesare Gargioli, Paolo Swuec, Mirko Cortese, Alexandra Stolz, Ramachandra M Bhaskara, Paolo Grumati +20 moredoaj +1 more sourceThe mammalian ULK1 complex and autophagy initiation [PDF]
, 2017 Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to persist could be detrimental to the cell.Bach, Bento, Chan, Chan, Chauhan, Chen, Cheong, Chude, Di Bartolomeo, Dunlop, Egan, Egan, Farre, Fullgrabe, Gammoh, Gan, Gan, Ganley, Henckaerts, Hieke, Hosokawa, Hosokawa, Ian G. Ganley, Itakura, James T. Murray, Jiang, Jon D. Lane, Joo, Jung, Kaizuka, Kaizuka, Karanasios, Karanasios, Kim, Konno, Koyama-Honda, Kundu, Lamark, Lazarou, Lazarus, Lee, Li, Li, Li, Li, Lim, Lin, Lin, Liu, Liu, Maria Zachari, McWilliams, Mercer, Nazio, Nazio, Ochaba, Orsi, Pengo, Petherick, Pickrell, Pike, Puente, Puri, Qi, Rabanal-Ruiz, Rui, Russell, Sarraf, Schneider, Sellier, Su, Sun, Suzuki, Tian, Torii, Ugolino, Viktor I. Korolchuk, Wang, Webster, Wold, Wong, Wu, Xu, Yang, Young, Yun, Zhou, Zou +87 morecore +2 more sourcesCarvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells
Journal of Dairy Science: Mastitis is a common disease in dairy cows and has various causes. Because of its enormous negative impact on cow health, welfare, and productivity, it results in huge economic losses and threatens sustainability of the dairy industry.Yue Yang, Ming Li, Jingyi Wang, Huijing Zhang, Renxu Chang, Bichen Zhao, Ben Aernouts, Qingnian Huang, Chuang Xu +8 moredoaj +1 more source
