Results 121 to 130 of about 3,252 (178)
Choline kinase inhibition promotes ER-phagy
Journal of Lipid Research, 2022 Mahtab Tavasoli +2 more
openaire +3 more sources
Lysosomal degradation of ER client proteins by ER-phagy and related pathways [PDF]
The endoplasmic reticulum (ER) is a major site of cellular protein synthesis. Degradation of overabundant, misfolded, aggregating or unwanted proteins is required to maintain proteostasis and avoid the deleterious consequences of aberrant protein ...
Jimenez-Moreno, Natalia +2 more
core +1 more source
Autophagy in liver diseases: A matter of what to remove and whether to keep [PDF]
, 2018 Yin, Xiao-Ming
core +1 more source
Scientific ReportsPeriodontitis is a chronic inflammatory disease that mainly occurs in the dental supporting tissues. Endoplasmic reticulum autophagy (ER-phagy) is a new type of selective autophagy. The main function of ER-phagy is to degrade excess ER membranes or toxic
Ruyue Wang +8 more
doaj +1 more source
Basal autophagy is involved in the degradation of the ERAD component EDEM1 [PDF]
, 2018 .: Little is known about the fate of machinery proteins of the protein quality control and endoplasmic reticulum(ER)-associated degradation (ERAD).
Gaplovska-Kysela, K. +5 more
core
Multiple genes core to ERAD, macroautophagy and lysosomal degradation pathways participate in the proteostasis response in α1-antitrypsin deficiency [PDF]
BACKGROUND & AIMS: In the classic form of α1-antitrypsin deficiency (ATD), the misfolded α1-antitrypsin Z (ATZ) variant accumulates in the endoplasmic reticulum (ER) of liver cells.
et al., +8 more
core +2 more sources
Roles of mitophagy in cellular physiology and development [PDF]
, 2017 The autophagic degradation of mitochondria, or mitophagy, has been shown to occur in eukaryotic cells under various physiological conditions. Broadly, these fall into two categories: quality-control related mitophagy and developmentally induced ...
Abeliovich, Hagai, Dengjel, Jörn
core