Results 101 to 110 of about 1,296,012 (206)

Yeast Bax Inhibitor, Bxi1p, Is an ER-Localized Protein that Links the Unfolded Protein Response and Programmed Cell Death in \u3cem\u3eSaccharomyces cerevisiae\u3c/em\u3e [PDF]

, 2011
Bax inhibitor-1 (BI-1) is an anti-apoptotic gene whose expression is upregulated in a wide range of human cancers. Studies in both mammalian and plant cells suggest that the BI-1 protein resides in the endoplasmic reticulum and is involved in the ...
Austriaco, Nicanor, Cascio, Vincent, Cebulski, James, Malouin, Joshua, Pinches, Nathan   +4 more
core   +1 more source

EFP1 is an ER stress-induced glycoprotein which interacts with the pro-apoptotic protein Par-4 [PDF]

, 2009
We have isolated the rat ortholog of EFP1 (EF-hand binding protein 1) as a novel interaction partner of the pro-apoptotic protein Par-4 (prostate apoptosis response-4).
Appel, Sarah, Boosen, Meike, Koplin, Ansgar, Maertens, Barbara, Preuss, Ute, Vetterkind, Susanne   +5 more
core   +1 more source

Carvacrol alleviates endoplasmic reticulum stress and inflammation induced by lipopolysaccharide by enhancing endoplasmic reticulum autophagy in dairy mammary epithelial cells

Journal of Dairy Science
: Mastitis is a common disease in dairy cows and has various causes. Because of its enormous negative impact on cow health, welfare, and productivity, it results in huge economic losses and threatens sustainability of the dairy industry.
Yue Yang, Ming Li, Jingyi Wang, Huijing Zhang, Renxu Chang, Bichen Zhao, Ben Aernouts, Qingnian Huang, Chuang Xu   +8 more
doaj   +1 more source

Lipid‐mediated ER stress

The FASEB Journal, 2008
Cell dysfunction and cell death induced by lipid accumulation in non‐adipose tissues, or lipotoxicity, may contribute to the pathogenesis of diabetes and obesity. We have investigated this pathophysiological response in a cell culture model in which growth media is supplemented with excess palmitic acid.
openaire   +1 more source

Electrical controlled rheology of a suspension of weakly conducting particles in dielectric liquid [PDF]

, 2006
The properties of suspensions of fine particles in dielectric liquid (electrorheological fluids) subjected to an electric field lead to a drastic change of the apparent viscosity of the fluid. For high applied fields (~ 3-5 kV/mm) the suspension congeals
Ayela, F., Foulc, J. -N., Guegan, Quentin, Tillement, O.   +3 more
core   +2 more sources

Obesity and ER Stress

The Korean Journal of Obesity, 2011
비만은 비정상적인 또는 과다한 지방의 축적에 따른 건 강의 위협상태로 정의된다. 이미 전 세계적으로 5번째로 많 은 사망요인으로 보고된 비만에 의해 매년 적어도 280만명 이상의 성인이 사망한다. 세계보건기구 (WHO)의 2008년도 보고서에 따르면, 전 세계적으로 약 15억의 성인이 과체중 을 보이며, 그 중 5억명이 비만인구로 분류된다. 이와 같은 비만은 특히 고지방, 고염류, 고탄수화물의 음식 섭취와 도 시화에 따른 운동부족에 따른 섭취한 열량과 소모한 열량의 불균형을 그 근본적 원인으로 판단할 수 있다. 비만은 또한 당뇨병의 44%, 심혈관 질환의 23%, 그리고 기타 비만관련 암질환의 7~40%의 발병원인으로 보고되고
openaire   +1 more source

ER stress shapes muscle

The Journal of Cell Biology, 2005
On page 555, Nakanishi et al. show that ER stress triggers apoptosis during muscle development. It is the ER stress pathway's first appearance in a nonpathological context. As muscle precursor cells called myoblasts differentiate, they fuse into multinucleated myotubes.
openaire   +2 more sources

Insulin reduces endoplasmic reticulum stress‐induced apoptosis by decreasing mitochondrial hyperpolarization and caspase‐12 in INS‐1 pancreatic β‐cells

Physiological Reports
Pancreatic β‐cell mass is a critical determinant of insulin secretion. Severe endoplasmic reticulum (ER) stress causes β‐cell apoptosis; however, the mechanisms of progression and suppression are not yet fully understood.
Nanako Murata, Kana Nishimura, Naoki Harada, Tomoya Kitakaze, Eiji Yoshihara, Hiroshi Inui, Ryoichi Yamaji   +6 more
doaj   +1 more source

Heat shock factor-1 alleviates ER-stress in Caenorhabditis elegans. [PDF]

Sci Rep
Ahmed S, Kovács D, Kovács M, Kosztelnik M, Hotzi B, Sigmond T, Saskői É, Vincze VV, Erdélyi V, Deák V, Stiller I, Vellai T, Barna J.   +12 more
europepmc   +1 more source

Posttranscriptional reprogramming controls MASLD progression through chronic ER stress adaptation. [PDF]

Sci Adv
Belloc E, Calderone V, Naranjo-Suarez S, Mateo L, Martin J, Malizia F, Sibilio A, Chanes V, Ramirez-Pedraza M, Delgado ME, Drebber U, Rheinwalt KP, Klein S, Brol MJ, Schierwagen R, Trebicka J, Aloy P, Fernandez M, Mendez R.   +18 more
europepmc   +1 more source