Results 111 to 120 of about 6,026 (227)
PLoS ONE, 2014 Behçet's disease (BD) is a multifactorial disorder associated with the HLA region. Recently, the ERAP1 gene has been proposed as a susceptibility locus with a recessive model and with epistatic interaction with HLA-B51.
Marta Conde-Jaldón +17 more
doaj +1 more source
PLoS ONE, 2020 BACKGROUND:Behçet's disease (BD) is a chronic multi-systemic vasculitis with a considerable prevalence in Asian countries. There are many genes associated with a higher risk of developing BD, one of which is endoplasmic reticulum aminopeptidase-1 (ERAP1).
Parisa Riahi +9 more
doaj +1 more source
RMD Open, 2020 Objective To determine the association between endoplasmic reticulum aminopeptidase (ERAP)1 and ERAP2 single-nucleotide polymorphisms (SNPs) and human leukocyte antigens (HLA)-B27+ or HLA-B15+ patients with spondyloarthritis (SpA).Methods 104 patients ...
Ruben Burgos-Vargas +16 more
doaj +1 more source
ENDOPLASMIC RETICULUM AMINO PEPTIDASE 1 (ERAP1) IN ANKYLOSING SPONDYLITIS
Romanian Journal of Rheumatology, 2015 Recently, endoplasmic reticulum aminopeptidase 1 (ERAP1) gene polymorphisms were associated with ankylosing spondylitis (AS) in genome-wide association studies (GWAS), associations which later were replicated across different populations, including the Romanian population.
Marius Cherciu +4 more
openaire +1 more source
Genetic and Genomic Approaches to the Study of Drug‐Induced Liver Injury
Liver International, Volume 45, Issue 1, January 2025.ABSTRACT Idiosyncratic hepatotoxicity induced by prescribed drugs has been known since the early 20th century. Identifying risk factors, including genetic factors, that trigger this drug‐induced liver injury (DILI) has been an important priority for many years, both to prevent drugs that cause liver injury being licensed and as a potential means of ...
Ann K. Daly
wiley +1 more source
Arthritis Research & Therapy, 2019 Background To investigate the association between 12 single nucleotide polymorphisms (SNPs) located on ERAP1 and IL23R with the presence of inflammation on the sacroiliac joint (SIJ) or spinal magnetic resonance imagery (MRI) in an early onset ...
Adeline Ruyssen-Witrand +6 more
doaj +1 more source
Charity auctions for the happy few [PDF]
, 2008 Recent literature has shown that all-pay auctions raise more money for charity than winner-pay auctions. We demonstrate that the first and second-price winner-pay auctions generate higher revenue than first-price all-pay auctions when bidders are ...
Bos, Olivier
core
High throughput analysis of epistasis in genome-wide association studies with BiForce [PDF]
, 2012 Motivation: Gene–gene interactions (epistasis) are thought to be important in shaping complex traits, but they have been under-explored in genome-wide association studies (GWAS) due to the computational challenge of enumerating billions of single ...
Attila Gyenesei +49 more
core +1 more source
Editorial: Endoplasmic Reticulum and Its Role in Tumor Immunity. [PDF]
, 2015 Published onlineJournal ArticleN/
Bremer, E, Eggleton, P, Michalak, M
core +3 more sources
Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis
Annals of the Rheumatic Diseases, 2010 To assess whether there is excess transmission of alleles from the ERAP1 ERAP2 locus in families with ankylosing spondylitis (AS).199 multiplex families with AS with four non-synonymous single nucleotide polymorphisms (SNPs), three in the endoplasmic reticulum aminopeptidase 1 (ERAP1) gene (rs27044, rs10050860 and rs30187) and one in the endoplasmic ...
Florence W L, Tsui +6 more
openaire +3 more sources