Results 101 to 110 of about 3,350 (175)

Characterization of ERAP1 rs30187 and rs10050860 Polymorphisms and Their Association with Ankylosing Spondylitis in The Algerian Population Association of ERAP1 in Algeria

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology, 2022
Azzoune, Asmaa, Benzaoui, Ahmed, Amroun, Habiba, Dahmani, Amira, Petit Elisabeth, Boudjema, Abdallah   +5 more
openaire   +1 more source

ERAP1-dependent antigen cross-presentation determines efficacy of adoptive T cell therapy in mice

, 2018
Cytotoxic T lymphocytes can reject established tumors if their target peptide is efficiently presented by major histocompatibility complex class I molecules (pMHC-I) on the surface of cancerous cells.
Peter-Michael Kloetzel, Ulrike Seifert, Thomas Blankenstein, Willimsky, G., Textor, A., Blankenstein, T., Kloetzel, P.M., Kühl, A.A., Christin Keller, Anja A. Kühl, Schmidt, K., Seifert, U., Gerald Willimsky, Ana Textor, Karin Schmidt, Keller, C.   +15 more
core   +1 more source

Optimization of potent and selective cyclohexyl acid ERAP1 inhibitors using structure- and property-based drug design [PDF]

Endoplasmic reticulum aminopeptidase 1 (ERAP1) cleaves the N-terminal amino acids of peptides, which can then bind onto major histocompatibility class I (MHC-I) molecules for presentation onto the cell surface, driving the activation of adaptive immune ...
Lindsay, David M., Lonsdale, Richard, Tayler, Chloe L., Young, Robert J., Hackett, Andrew S., Schneck, Jessica L., Scott-Stevens, Paul, Walker, Ann L., Convery, Máire A., Rowedder, James E., Lea, Jonatahn D., Hryczanek, Ross P., Nickels, Leng, Temponeras, Ioannis, Kitchen, Semra, Holmes, Duncan S., Hutchinson, Jonathan P., Neu, Margarete, Rowland, Paul, Phillipou, Alex, Wojno-Picon, Justyna, Tinworth, Christopher P., Liddle, John, Chung, Chun-wa, Stratikos, Efstratios, Law, Robert P., Korczynska, Justyna, Sheehan, Hester   +27 more
core   +1 more source

Sex-dependent effects of ERAP1 deficiency [PDF]

Nature Reviews Nephrology, 2019
openaire   +2 more sources

Association of IL23R and ERAP1 genes with ankylosing spondylitis in a Portuguese population.

Clinical and experimental rheumatology, 2009
Association between ankylosing spondylitis (AS) and two genes, ERAP1 and IL23R, has recently been reported in North American and British populations. The population attributable risk fraction for ERAP1 in this study was 25%, and for IL23R, 9%. Confirmation of these findings to ERAP1 in other ethnic groups has not yet been demonstrated.
Pimentel-Santos, F. M., Ligeiro, D., Matos, M., Mourao, A. F., Sousa, E., Pinto, P., Ribeiro, A., Sousa, M., Barcelos, A., Godinho, F., Cruz, M., Fonseca, J. E., Guedes-Pinto, H., Trindade, H., Evans, D. M., Brown, M. A., Branco, J. C.   +16 more
openaire   +5 more sources

Geneticheskie prediktory ankiloziruyushchego spondilita

КардиоСоматика, 2015
Анкилозирующий спондилит (АС) - хроническое воспалительное заболевание позвоночника (спондилит) и крестцово-подвздошных суставов (сакроилеит), нередко протекающее с поражением периферических суставов (артрит) и энтезисов (энтезит), а в ряде случаев ...
V. S Mordovskiy, A. S Kents, S. Yu Nikulina, A. A Chernova, E. V Kapustina, T. Yu Bol'shakova   +5 more
doaj  

ERAP1 and PDE8A Are Downregulated in Cattle Protected against Bovine Tuberculosis.

Journal of molecular microbiology and biotechnology, 2017
Fil: Bigi, Fabiana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Instituto Nacional de Tecnología Agropecuaria. Centro de Investigación en Ciencias Veterinarias y Agronómicas.
Blanco, Federico Carlos, Soria, Marcelo Abel, Klepp, Laura Ines, Bigi, Fabiana   +3 more
openaire   +2 more sources

Messing with Signal 1: How Perturbed MHC Class I Antigen Presentation Contributes to Cancer. [PDF]

Cells
Lawand M, Al Rayess S, Jaber R, van Endert P.   +3 more
europepmc   +1 more source

Leveraging expression quantitative trait loci information in single-cell resolution to identify cell-specific genes for gestational diabetes. [PDF]

PLoS One
Zhu W, Wu X, Hu R.
europepmc   +1 more source

Research advancements in DNA methylation pertaining to ankylosing spondylitis. [PDF]

Front Immunol
Xia R, Qiu Z, Kong S, Ning Y, Zhu W, Yang K.   +5 more
europepmc   +1 more source