Decoding eQTLs: unraveling their role in spondyloarthropathies pathogenesis and potential therapeutics. [PDF]
Front ImmunolAwadh NI +6 more
europepmc +1 more source
Decoding the inflammatory-osteogenic axis in ankylosing spondylitis: mechanisms, dysregulation, and emerging therapeutic interventions. [PDF]
Front ImmunolParvin A +7 more
europepmc +1 more source
Integrated Host Genetics and Skin Microbiome Profiling Suggest an HLA-C-Peptostreptococcus Axis in Psoriasis. [PDF]
Int J Mol SciSeifert O +3 more
europepmc +1 more source
p53 regulates early mucosal immunity via antigen presentation in zebrafish intestine post-SVCV vaccination. [PDF]
Cell Commun SignalZhao Z +6 more
europepmc +1 more source
ERAP1 Activity Modulates the Immunopeptidome but Also Affects the Proteome, Metabolism, and Stress Responses in Cancer Cells. [PDF]
Mol Cell ProteomicsNikopaschou M +10 more
europepmc +1 more source
Exploring the Genetic Association and Genetic Architecture of Iridocyclitis and Extraocular Autoimmune Diseases. [PDF]
Transl Vis Sci TechnolYuan F, Pu K, Li L, Song H.
europepmc +1 more source
Mechanistic insights into how gut homeostasis and immune-system crosstalk shape ankylosing spondylitis. [PDF]
Front ImmunolLi J, Xie X.
europepmc +1 more source
The murine MHC-E molecule Qa-1<sup>b</sup> is surface displayed in a peptide-free conformation in homeostasis. [PDF]
Front ImmunolSchaap G +10 more
europepmc +1 more source
ERAP1 modulation as an innovative strategy for cancer treatment
The recent development of immune checkpoint blockade (ICB)-mediated immunotherapy has achieved outstanding clinical results in patients with a broad spectrum of cancer types, improving their overall survival. Despite the encouraging results, the number of patients who can benefit and have a long-term response to treatment is limited.
openaire +1 more source
Discovery of Novel Allosteric Inhibitor Hits for Insulin-Regulated Aminopeptidase Provides Insights on Enzymatic Mechanism. [PDF]
ACS OmegaGeorgaki G +5 more
europepmc +1 more source