Results 141 to 150 of about 3,465 (162)

Epistasis of ERAP1 With 4 Major Histocompatibility Complex Class I Alleles in Frontal Fibrosing Alopecia: A Genome-Wide Association Study Meta-Analysis.

JAMA Dermatol
Rayinda T, Dand N, McSweeney SM, Christou E, Ung CY, Stefanato CM, Fenton DA, Harries M, Palamaras I, Tidman A, Holmes S, Koutalopoulou A, Ardern-Jones M, Kaur M, Papanikou S, Chasapi V, Vañó-Galvan S, Saceda-Corralo D, Melián-Olivera A, Azcarraga-Llobet C, Lobato-Berezo A, Bustamante M, Sunyer J, Starace MVR, Piraccini BM, Wiss IP, Senna MM, Singh R, Hillmann K, Kanti-Schmidt V, Blume-Peytavi U, McGrath JA, Simpson MA, Tziotzios C.   +33 more
europepmc   +1 more source

Error in Author Affiliation.

JAMA Dermatol
europepmc   +1 more source

ERAP1: A Potential Therapeutic Target for a Myriad of Diseases

Expert Opinion on Therapeutic Targets, 2020
Introduction: Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) is a key regulator of the peptide repertoire displayed by Major Histocompatibility Complex I (MHC I) to circulating CD8 + T cells and NK cells.
Edward James, Emma Reeves
exaly   +2 more sources

ERAP1/ERAP2 And RUNX3 Polymorphisms Are Not Associated With Ankylosing Spondylitis Susceptibility in Chinese Han

Clinical and Experimental Immunology, 2018
Summary Previous studies show that endoplasmic reticulum-associated aminopeptidase (ERAP1/ERAP2) and runt-related transcription factor 3 (RUNX3) gene polymorphisms are associated with AS (ankylosing spondylitis) in European Caucasians ...
Peizeng Yang, A Kijlstra
exaly   +2 more sources

Functionally Distinct ERAP1 Allotype Combinations Distinguish Individuals With Ankylosing Spondylitis

Proceedings of the National Academy of Sciences of the United States of America, 2014
For more than 40 y, expression of HLA-B27 has been strongly associated with the chronic inflammatory disease Ankylosing Spondylitis (AS); however, the mechanisms underlying this association are still unknown.
Edward James, Christopher J. Edwards, Tim Elliott   +2 more
exaly   +2 more sources

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Functional ERAP1 Variants Distinctively Associate With Ankylosing Spondylitis Susceptibility Under the Influence of HLA-B27 in Taiwanese

Cells, 2022
Ji-Yih Chen, Jing-Chi Lin, Jianming Wu
exaly  

Discovery and Optimization of a Series of Benzofuran Selective ERAP1 Inhibitors: Biochemical and in Silico Studies

ACS Medicinal Chemistry Letters, 2021
Nicolas Basse
exaly  

ERAP1 Association With Ankylosing Spondylitis Is Attributable to Common Genotypes Rather Than Rare Haplotype Combinations

Proceedings of the National Academy of Sciences of the United States of America, 2017
Paul Wordsworth, Adrian Cortes, Matteo Vecellio   +2 more
exaly  

Crystal Structures of the Endoplasmic Reticulum Aminopeptidase-1 (ERAP1) Reveal the Molecular Basis for N-Terminal Peptide Trimming

Proceedings of the National Academy of Sciences of the United States of America, 2011
Paul Wordsworth, Benedikt M. Kessler, Roman Fischer   +2 more
exaly