Results 81 to 90 of about 5,215 (208)
Mediators of Inflammation, Volume 2026, Issue 1, 2026.Heat ablation techniques, such as microwave and radiofrequency ablation, are established interventions for hepatocellular carcinoma (HCC). However, incomplete ablation often leads to angiogenesis‐driven metastasis and recurrence, undermining long‐term treatment efficacy.
Zhuoyang Fan +7 more
wiley +1 more source
The interplay between viral-derived miRNAs and host immunity during infection [PDF]
, 2019 MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad +3 more
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Structural bases for MHC class I peptide selection and neoepitope formation [PDF]
, 2018 One task of the immune system is to distinguish between healthy cells and altered cells due to viruses or cancers. To achieve this CD8+ T-cells are constantly monitoring the Major histocompatibility class I (MHC-I) complexes expressed on all nucleated ...
Hafstrand, Ida
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Advanced Science, Volume 12, Issue 36, September 25, 2025.Tryptophan metabolite Indole‐3‐aldehyde (I3A) downregulates cytosolic AhR and p‐ERK/c‐MYC proteins, together enhancing STAT3 phosphorylation and tumor immunogenicity. Overexpression of the Trp metabolic enzyme interleukin‐4‐induced gene‐1 (IL4I1) in tumor cells increases intracellular levels of I3A and enhances tumor immunogenicity.
Lei Cui +19 more
wiley +1 more source
The epidemiology of childhood psoriasis: a scoping review [PDF]
, 2016 Psoriasis is an inflammatory noncommunicable skin disease that affects both adults and children. At present, the epidemiology and natural history of psoriasis are not widely understood.
Adaji, Enemona +5 more
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Cell Proliferation, Volume 58, Issue 9, September 2025.This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan +5 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 16, August 2025.ABSTRACT Colorectal cancer (CRC) patients have had limited benefits from conventional chemotherapy, highlighting the need for improved therapeutic strategies. Natural compounds have emerged as promising alternatives due to their potent anti‐cancer properties and reduced side effects.
Peng Ouyang +10 more
wiley +1 more source
The Turkish Journal of Gastroenterology, 2016 Background/Aims: To establish the prevalence of the single nucleotide polymorphisms (SNPs) of endoplasmic reticulum aminopeptidase 1 (ERAP1), IL-23 receptor (IL-23R), signal transducer and activator of transcription 3 (STAT-3) and Janus kinase 2 (JAK-2 ...
Orhan Küçükşahin +13 more
doaj +1 more source
Polymorphisms in ERAP1 and ERAP2 Genes Are Associated With Tuberculosis in the Han Chinese
Frontiers in Genetics, 2020 Single nucleotide polymorphisms (SNPs) in the endoplasmic reticulum aminopeptidase (ERAP1 and ERAP2) genes are associated with the pathogenesis of bacterial and viral infections.
Shuqiong Zhang +12 more
doaj +1 more source
A Review of the Molecular and Genetic Foundations of Ankylosing Spondylitis [PDF]
, 2012 Ankylosing Spondylitis (AS) is an autoimmune disease that occurs in an adult-onset or juvenile-onset form. The symptoms, severity, and prevalence of this disease vary according to sex, age, and race.
Dowlearn, Emily
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