Results 121 to 130 of about 6,026 (227)

A comparative Genome-Wide Association Interaction study using BOOST and MB-MDR algorithms on Ankylosing Spondylitis [PDF]

open access: yes, 2013
Genome-Wide Association (GWA) studies have gained popularity after the completion of the Human Genome Project and advancement of high-throughput technologies. These studies aim to scan thousands of genomic variations (e.g., SNPs) for their association to
Bessonov, Kyrylo
core  

New insights into the genetic component of non-infectious uveitis through an Immunochip strategy [PDF]

open access: yes, 2016
Background: Large-scale genetic studies have reported several loci associated with specific disorders involving uveitis. Our aim was to identify genetic risk factors that might predispose to uveitis per se, independent of the clinical diagnosis, by ...
Adán, Alfredo   +23 more
core   +2 more sources

Prevalence of genetic risk factors of psoriasis among the population of the Russian Federation

open access: yesVestnik Dermatologii i Venerologii, 2017
Goal. To assess the prevalence of polymorphisms of genes of the predisposition to psoriasis among the population of the Russian Federation. Materials and methods. The authors examined 546 psoriasis patients and 206 healthy people. The polymorphism of the
A. A. Kubanov   +3 more
doaj   +1 more source

Charity Auctions for the Happy Few [PDF]

open access: yes
Recent literature has shown that all-pay auctions raise more money for charity than winner-pay auctions. We demonstrate that the first-price and second-price winner-pay auctions outperform the first-price and second-price all-pay auction when bidders are
Olivier Bos
core  

The interplay between viral-derived miRNAs and host immunity during infection [PDF]

open access: yes, 2019
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad   +3 more
core   +1 more source

How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins

open access: yesFrontiers in Immunology, 2018
Four inflammatory diseases are strongly associated with Major Histocompatibility Complex class I (MHC-I) molecules: birdshot chorioretinopathy (HLA-A*29:02), ankylosing spondylitis (HLA-B*27), Behçet's disease (HLA-B*51), and psoriasis (HLA-C*06:02). The
José A. López de Castro
doaj   +1 more source

Apprêtement des antigènes présentés par les molécules de classe I du CMH [PDF]

open access: yes, 2006
Les défenses immunitaires de l’organisme vis-à-vis des agents pathogènes et des cellules malignes reposent en grande partie sur la surveillance par les lymphocytes T cytotoxiques.
Endert, Peter van
core  

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Virtual drug screening study to discover novel ERAP1 allosteric site inhibitors for the treatment of ankylosing spondylitis (AS)

open access: yesJournal of Research in Pharmacy
Endoplasmic reticulum aminopeptidase 1 (ERAP1) is one of the key molecules in the antigen presentation process. To date, associations of ERAP1 with Ankylosing Spondylitis (AS) have been revealed with strong data. As such, to target the allosteric site of
Hüseyin Portakal   +2 more
semanticscholar   +1 more source

Deciphering ERAP1 in Cancer: Machine Learning for Protein Detection and Therapeutic Implications

open access: yesAcademic Journal of Computing & Information Science
: ERAP1 plays a pivotal role in processing antigenic peptides for presentation on major histocompatibility complex (MHC) class I molecules (Li et al. [1]).
Chloe Cheng
semanticscholar   +1 more source

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