Results 121 to 130 of about 6,026 (227)
A comparative Genome-Wide Association Interaction study using BOOST and MB-MDR algorithms on Ankylosing Spondylitis [PDF]
Genome-Wide Association (GWA) studies have gained popularity after the completion of the Human Genome Project and advancement of high-throughput technologies. These studies aim to scan thousands of genomic variations (e.g., SNPs) for their association to
Bessonov, Kyrylo
core
New insights into the genetic component of non-infectious uveitis through an Immunochip strategy [PDF]
Background: Large-scale genetic studies have reported several loci associated with specific disorders involving uveitis. Our aim was to identify genetic risk factors that might predispose to uveitis per se, independent of the clinical diagnosis, by ...
Adán, Alfredo +23 more
core +2 more sources
Prevalence of genetic risk factors of psoriasis among the population of the Russian Federation
Goal. To assess the prevalence of polymorphisms of genes of the predisposition to psoriasis among the population of the Russian Federation. Materials and methods. The authors examined 546 psoriasis patients and 206 healthy people. The polymorphism of the
A. A. Kubanov +3 more
doaj +1 more source
Charity Auctions for the Happy Few [PDF]
Recent literature has shown that all-pay auctions raise more money for charity than winner-pay auctions. We demonstrate that the first-price and second-price winner-pay auctions outperform the first-price and second-price all-pay auction when bidders are
Olivier Bos
core
The interplay between viral-derived miRNAs and host immunity during infection [PDF]
MicroRNAs are short non-coding RNAs that play a crucial role in the regulation of gene expression during cellular processes. The host-encoded miRNAs are known to modulate the antiviral defense during viral infection.
Ingle, Harshad +3 more
core +1 more source
How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins
Four inflammatory diseases are strongly associated with Major Histocompatibility Complex class I (MHC-I) molecules: birdshot chorioretinopathy (HLA-A*29:02), ankylosing spondylitis (HLA-B*27), Behçet's disease (HLA-B*51), and psoriasis (HLA-C*06:02). The
José A. López de Castro
doaj +1 more source
Apprêtement des antigènes présentés par les molécules de classe I du CMH [PDF]
Les défenses immunitaires de l’organisme vis-à-vis des agents pathogènes et des cellules malignes reposent en grande partie sur la surveillance par les lymphocytes T cytotoxiques.
Endert, Peter van
core
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Endoplasmic reticulum aminopeptidase 1 (ERAP1) is one of the key molecules in the antigen presentation process. To date, associations of ERAP1 with Ankylosing Spondylitis (AS) have been revealed with strong data. As such, to target the allosteric site of
Hüseyin Portakal +2 more
semanticscholar +1 more source
Deciphering ERAP1 in Cancer: Machine Learning for Protein Detection and Therapeutic Implications
: ERAP1 plays a pivotal role in processing antigenic peptides for presentation on major histocompatibility complex (MHC) class I molecules (Li et al. [1]).
Chloe Cheng
semanticscholar +1 more source

