Results 111 to 120 of about 57,515 (223)

Nuclear ErbB-2: A Novel Therapeutic Target in ErbB-2-Positive Breast Cancer?

, 2019
Membrane overexpression of ErbB-2 (MErbB-2), a member of the ErbB family of receptor tyrosine kinases, occurs in 15– 20% of breast cancers (BC) and constitutes a therapeutic target in this BC subtype (ErbB-2-positive).
Elizalde, Patricia Virginia, Madera, Santiago, Cordo Russo, Rosalia Ines, Charreau, Eduardo Hernan, Chervo, María Florencia   +4 more
core   +1 more source

Prognostic impact of p53, c-erbB-2 and epidermal growth factor receptor on head and neck carcinoma

São Paulo Medical Journal
CONTEXT: p53, c-erbB-2 and epidermal growth factor receptor (EGFR) are cancer-related proteins that are usually expressed in head and neck squamous cell carcinoma (SCC). Their prognostic value remains controversial.
Orlando Parise Junior, Leda Viegas Carvalho, Roberto Elias Villela Miguel, Luiz Paulo Kowalski   +3 more
doaj   +1 more source

Kolorektal kanser ve kolorektal prekanseröz adenom olgularında c-erbB-2 ve c-erbB-3 reseptör ekspresyonunun değerlendirilmesi

, 2003
76 ÖZET Tümör oluşumunun en mükemmel modeli kolorektal kanser gelişimidir. Kolon kanser oluşumunda pek çok genetik ve epigenerik değişiklikler tespit edilmiştir. Ancak kolorektal kan serler halen tüm dünyada mortaliteye neden olan 4. kanserdir.
FATMA AYERDEN EBİNÇ
core  

Mammalian cell transformation by a murine retrovirus vector containing the avian erythroblastosis virus erbB gene

, 1986
A recombinant murine retrovirus vector containing the v-erbB gene of avian erythroblastosis virus was constructed to investigate v-erbB as a transforming gene for mammalian cells.
J. H. Pierce, M. H. Kraus, A. Gazit, S. A. Aaronson, P. P. Di Fiore, C. Y. Pennington   +5 more
core   +1 more source

erbB 基因表达与乳腺癌发生的相关关系

Zhongshan Daxue xuebao. Yixue kexue ban, 1998
目的: 研究 c -erbB-2, c-erbB-4 原癌基因过度表达与乳腺癌发生及其病理参数的相关关系。方法: 对 122 例乳腺疾病石蜡切块,其 中 80 例乳腺癌, 16 例乳腺纤维腺瘤, 9 例乳腺纤维囊性病, 17 例乳腺癌转移淋巴结均采用免疫组化( LSAB 法)结合计算机图象分析研究原癌 基因产物 c-erbB-2, c-erbB-4的表达情况。结果: c-erbB-2 在乳腺癌中存在过度表达, P
doaj  

Vascular endothelial growth factor, c-erbB-2 and c-erbB-3 expression in colorectal adenoma and adenocarcinoma

, 2005
Aim: To analyze vascular endothelial growth factor (VEGF), c-erbB-2 and c-erbB-3 expression and to evaluate their relation to clinicopathologic parameters and pathogenesis of colorectal carcinoma.
Ebinc, FA, Akyurek, X, Dursun, A, Unsal, D, Mentes, BB, Uner, A   +5 more
core  

Assessment of staging, prognosis and mortality of colorectal cancer by tumor markers: receptor erbB-2 and cadherins

Acta Cirúrgica Brasileira, 2005
PURPOSE: To evaluate the prognostic significance and correlation with staging and degree of cell differentiation of the tumoral expression of the proteins c-erbB-2 and E-cadherin, in patients with colorectal adenocarcinoma.
Jesus Eliane C., Matos Delcio, Artigiani Ricardo, Waitzberg Angela F.L., Goldenberg Alberto, Saad Sarhan Sydney   +5 more
doaj  

C－erbB－2表达对乳腺浸润性导管癌预后的预测

Zhongshan Daxue xuebao. Yixue kexue ban, 1996
应用单克隆抗体Ｃ－ｅｒｂＢ－２肿瘤蛋白及免疫组化（ＬＳＡＢ）法，对８４例乳腺浸润性导管癌作Ｃ－ｅｒｂＢ－２癌基因蛋白产物表达（简称Ｃ－ｅｒｂＢ－２表达）检测并与随诊资料进行比较分析，结果（１）Ｃ－ｅｒｂＢ－２在本组病例的表达率为５５．９％（４７／８４）。（２）Ｃ－ｅｒｂＢ－２表达与肿瘤的ＴＮＭ分期、复发／远必转移、５ａ生存率无相关性（Ｐ＞０．０５）、而仅与腋淋巴结转移状况和２ａ死亡率有关（Ｐ＜０．００５及Ｐ＜０．０５）。（３）有／无淋巴结转移病例的Ｃ－ｅｒｂＢ－２表达与患者的预后均无关（Ｐ＞０．７５ ...
doaj  

Melanoma of the Scalp Harboring a Novel AGFG1::ERBB4 Fusion: A Case Report With Clinicopathologic and Genomic Characterization. [PDF]

Genes Chromosomes Cancer
Cao X, Yu H, Muldrew KL, Johnson RM, Liang L, Pei Y, Huttenbach YT, Yin CC, Zhang S.   +8 more
europepmc   +1 more source

ErbB [PDF]

, 2019
openaire   +1 more source