Results 61 to 70 of about 57,515 (223)
Interaction between ErbB‐1 and ErbB‐2 transmembrane domains in bilayer membranes
FEBS Letters, 2002 The transmembrane domains of ErbB receptor tyrosine kinases are monotopic helical structures proposed to be capable of direct side‐to‐side contact with related receptors. Formation of the resulting homo‐ or hetero‐oligomeric complexes is considered a key step in ligand‐mediated signalling.
Sharpe, Simon +2 more
openaire +2 more sources
Frontiers in Molecular Neuroscience, 2018 Increasing evidence demonstrates that the neurotrophic factor Neuregulin 1 (NRG1) and its receptors, ErbB tyrosine kinases, modulate midbrain dopamine (DA) transmission.
Ada Ledonne +2 more
doaj +1 more source
Developmental Dynamics, EarlyView.Development and differentiation of the atrial myocardium. Hemodynamic loading triggers shear stress response, which is essential for pectinate muscle formation; mechanical stretching is important for the expression of chamber myocardium markers and proper maturation of the atrial contractile and conductive properties.
C. Neradilova +7 more
wiley +1 more source
Synergistic Inhibition of ErbB Signaling by Combined Treatment with Seliciclib and ErbB-Targeting Agents [PDF]
Clinical Cancer Research, 2008 AbstractPurpose: The aims of this study were to investigate whether the cyclin-dependent kinase inhibitor seliciclib could synergize with agents that target ErbB receptors and to elucidate the molecular mechanism of the observed synergy.Experimental Design: Synergy between seliciclib and ErbB receptor targeted agents was investigated in various cell ...
Fleming, Ian N. +4 more
openaire +3 more sources
Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.Technological innovation through image analysis has become a reality. Radiation exposure is unavoidable during ERCP, yet reducing X‐ray dose degrades image quality. We evaluated an image‐processing technology (🄬Shimadzu) that reconstructs low‐dose fluoroscopic images to a quality comparable with standard‐dose images.
Mitsuru Okuno +9 more
wiley +1 more source
Novel Injectable Supports Long‐Term Recurrent Laryngeal Nerve and Partial Peripheral Nerve Repair
The Laryngoscope, EarlyView.Following recurrent laryngeal nerve transection in C57BL/6 mice, intramuscular Agrin, neuregulin‐1, and acetylcholine treatment of the thyroarytenoid muscle supported functional reinnervation and preservation of neuromuscular structure at 84 days.
Aditya Bhatt +10 more
wiley +1 more source
Folia Histochemica et Cytobiologica, 2010 The family of epidermal growth factor (EGF, EGFR, c-erbB-2) plays a pivotal role in gastric cancer progression, invasion and metastasizing. Helicobacter pylori infection is known to contribute significantly to the formation and progression of gastric ...
Andrzej Kemona +3 more
doaj +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
, 1999 Activation of erbB-1 receptors by glial TGFα has been shown to be a component of the developmental program by which the neuroendocrine brain controls mammalian sexual development.
Anda Cornea +7 more
core +1 more source
The International Journal of Biological Markers, 2004 Background The protein encoded by the c-erbB-2 gene is a membrane receptor expressed in a variety of solid human cancers and directly related to poor prognosis.
F.J. Vizoso +8 more
doaj +1 more source