Results 71 to 80 of about 61,149 (183)
The Dipole Potential Influences the Clustering of ErbB Proteins [PDF]
Tamás Kovács +3 more
openalex +1 more source
TROP2 is upregulated in CRC metastasis and promotes lactate overproduction via YBX1‐HIF‐1α signalling. TROP2 signalling induces H3K18la at metastasis genes promoters in CRC and promotes their expression. AccLactate sustains TROP2 expression in CRC cells via H3K18la Acriflavine suppresses TROP2‐driven CRLM by targeting the H3K18la/TROP2 feedback loop ...
Weifeng Wang +17 more
wiley +1 more source
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli +8 more
wiley +1 more source
c-erbB-4 protein expression in human breast cancer [PDF]
Thean Yean Kew +8 more
openalex +1 more source
Synergistic Strategies in Systemic Therapy for Advanced Hepatocellular Carcinoma
This article comprehensively examines the evolving landscape of systemic therapy for advanced hepatocellular carcinoma. It covers the progress in tyrosine kinase inhibitors and immune checkpoint inhibitors, analyzes the efficacy of novel combination strategies, and discusses current challenges like drug resistance and the lack of biomarkers.
Yongxin Yu +5 more
wiley +1 more source
Expression and Characterization of Kinase‐active v‐erbB Protein Using a Baculovirus Vector System [PDF]
Kaoru Morishita +6 more
openalex +1 more source
ABSTRACT Aims Guideline‐directed medical therapy (GDMT) implementation in heart failure with reduced ejection fraction (HFrEF) remains suboptimal. A computable algorithm was developed to generate a medication optimization score (MOS) and provide guideline‐based recommendations.
Mohamed S. Ali +5 more
wiley +1 more source
Epigen, the Last Ligand of ErbB Receptors, Reveals Intricate Relationships between Affinity and Mitogenicity [PDF]
Bose Kochupurakkal +15 more
openalex +1 more source
Increased activation of ErbB and NFκB signalling pathways in Darier disease affected skin
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Nancy Ernst +2 more
wiley +1 more source
Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice
Graded calorie restriction in male mice modified epigenetic signatures of the liver and slowed ageing rate in a graded manner. ABSTRACT DNA methylation variation is associated with chronological ageing. Calorie restriction (CR) prolongs lifespan and healthspan in many species.
Timothy P. Moulds +6 more
wiley +1 more source

