Results 71 to 80 of about 95,906 (268)
The Vietnamese swine as a translational model of invasive ductal carcinoma of the breast
Animal Models and Experimental Medicine, EarlyView.The flow diagram outlines the chemical induction of breast tumors through a single intraperitoneal dose of MNU. Tumor development was assessed using ultrasound and clinical examination. After 14 weeks, mammary tissue was collected and histologically analyzed to evaluate structural similarities between sows and humans, the carcinogenic potential of MNU,
Claudia Elizabeth Vera‐Tizatl +6 more
wiley +1 more source
Breast Cancer Research, 2017 Background The Cancer Genome Atlas analysis revealed that somatic EGFR, receptor tyrosine-protein kinase erbB-2 (ERBB2), Erb-B2 receptor tyrosine kinase 3 (ERBB3) and Erb-B2 receptor tyrosine kinase 4 (ERBB4) gene mutations (ERBB family mutations) occur ...
Sinead Toomey +23 more
doaj +1 more source
Synergistic Inhibition of ErbB Signaling by Combined Treatment with Seliciclib and ErbB-Targeting Agents [PDF]
Clinical Cancer Research, 2008 AbstractPurpose: The aims of this study were to investigate whether the cyclin-dependent kinase inhibitor seliciclib could synergize with agents that target ErbB receptors and to elucidate the molecular mechanism of the observed synergy.Experimental Design: Synergy between seliciclib and ErbB receptor targeted agents was investigated in various cell ...
Fleming, Ian N. +4 more
openaire +3 more sources
Animal Research and One Health, EarlyView.ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang +8 more
wiley +1 more source
Advances in Urology, 2012 The prognostic importance of examining ErbB receptor family expression in human bladder cancer remains uncertain. Using published evidence, we examined the clinical value and the updated results of clinical trials targeting ErbB receptor family members ...
Yuh-Shyan Tsai +3 more
doaj +1 more source
Transferrin-polycation conjugates as carriers for DNA uptake into cells. [PDF]
, 1990 We have developed a high-efficiency nucleic acid delivery system that uses receptor-mediated endocytosis to carry DNA macromolecules into cells. We accomplished this by conjugating the iron-transport protein transferrin to polycations that bind nucleic ...
Beug, Hartmut +4 more
core +1 more source
The Journal of Cell Biology, 2002 c-erbB receptors are usually located in cell membranes and are activated by extracellular binding of EGF-like growth factors. Unexpectedly, using immunofluorescence we found high levels of c-erbB-3 within the nuclei of MTSV1-7 immortalized nonmalignant human mammary epithelial cells.
Martin Offterdinger +3 more
openaire +1 more source
Animal Research and One Health, EarlyView.Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li +10 more
wiley +1 more source
Frontiers in Molecular Neuroscience, 2018 Organophosphate-induced delayed neuropathy (OPIDN) is characterized by progressive axonal degeneration and demyelination of the spinal cord and sciatic nerves.
Hai-Yang Xu +6 more
doaj +1 more source
Alterations of c-Myc and c-erbB-2 genes in ovarian tumours [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2009 Introduction. According to clinical and epidemiological studies, ovarian cancer ranks fifth in cancer deaths among women. The causes of ovarian cancer remain largely unknown but various factors may increase the risk of developing it, such as age, family ...
Pastor Tibor +8 more
doaj +1 more source