Results 141 to 150 of about 60,784 (262)

Increased activation of ErbB and NFκB signalling pathways in Darier disease affected skin

open access: yes
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Nancy Ernst   +2 more
wiley   +1 more source

The Neuroimmunome of Hepatitis Patients Associates With Disease Severity

open access: yesJournal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Hepatitis is a systemic disease marked by neuroimmune dysregulation beyond hepatic inflammation. Using a systems biology approach, we conducted transcriptomic meta‐analyses across in vitro models, liver tissues, and PBMCs from hepatitis virus‐infected patients to identify neuroimmune signatures.
Adriel Leal Nóbile   +18 more
wiley   +1 more source

Co-Targeting ErbB Receptors and the PI3K/AKT Axis in Androgen-Independent Taxane-Sensitive and Taxane-Resistant Human Prostate Cancer Cells. [PDF]

open access: yesCancers (Basel), 2022
Adediran S   +9 more
europepmc   +1 more source

AMPK‐Dependent Epigenetic Regulation of Metabolism Mediates the Anti‐Cancer Action of Pterostilbene in Hepatocellular Carcinoma

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 23, December 2025.
This study investigates the anti‐cancer effects of pterostilbene (PTS), a naturally occurring dietary phytoestrogen, in a rat model of hepatocellular carcinoma (HCC) induced by a choline‐deficient L‐amino acid‐defined (CDAA) diet. Supplementation with PTS significantly reduces liver steatosis and tumor formation.
Cayla Boycott   +12 more
wiley   +1 more source

A Global Transcriptomic Analysis Reveals Body Weight‐Specific Molecular Responses to Chronic Orange Juice Consumption in Healthy Individuals

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 24, December 2025.
This study aimed to investigate the molecular pathways involved in the health benefits of chronic orange juice (OJ) consumption through global transcriptomic approach in peripheral blood mononuclear cells (PBMCs). Healthy volunteers consumed 500 mL of OJ daily for 60 days.
Layanne Nascimento Fraga   +6 more
wiley   +1 more source

Breast Cancer Brain Metastasis: Bridging Biological Mechanisms to Therapeutic Innovations

open access: yesMedComm – Oncology, Volume 4, Issue 4, December 2025.
Breast cancer brain metastasis (BCBrM) is driven by a multistep metastatic cascade and shaped by dynamic tumor–brain interactions. This review integrates current mechanistic insights, from molecular signaling pathways to immune evasion, and evaluates preclinical models and emerging therapies.
Jing Feng   +3 more
wiley   +1 more source

Nano‐Mediated Fluorescence Switching for Epidermal Growth Factor Receptor Detection

open access: yesCell Proliferation, Volume 58, Issue 12, December 2025.
This study presents Cy3‐AptEGFR@BPNSs, a novel nano‐detector for real‐time, visual monitoring of EGFR expression in cancer cells. Addressing the limitations of current methods, this detector utilises fluorescence quenching/recovery, providing high specificity and sensitivity, with fluorescence intensity proportional to EGFR levels.
Xin Fu   +11 more
wiley   +1 more source

Uterine Serous Carcinoma Arising From Endometrial Polyp: A Case Report

open access: yesGynecology Obstetrics & Reproductive Medicine, 2009
Serous carcinoma is the prototype of type II endometrial carcinoma. A 71-year-old woman who had history of smoking, diabetes mellitus and hypertension admitted to the hospital with postmenopausal uterine bleeding.
Sibel Bektaş   +4 more
doaj  

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