The Agrin/MuSK Signaling Pathway Is Spatially Segregated from the Neuregulin/ErbB Receptor Signaling Pathway at the Neuromuscular Junction [PDF]
Jonathan C. Trinidad+2 more
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Advances in Bruton tyrosine kinase (Btk) inhibition are steered by Bruton tyrosine kinase phylogeny
Abstract Bruton tyrosine kinase (Btk) has long been known to play a key role in chronic lymphatic leukaemia, Waldenström macroglobulinaemia and other B‐cell proliferative disorders. An impressive programme of drug discovery and clinical development led to the approval of covalent and non‐covalent Btk inhibitors that became pillars of treatment of such ...
Giorgio Minotti+3 more
wiley +1 more source
Altered Gene Activity of Epidermal Growth Factor Receptor (ErbB-1) in the Hypothalamus of Aging Female Rat Is Linked to Abnormal Estrous Cycles [PDF]
Jingwen Hou+4 more
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Expression of ErbB receptors during pancreatic islet development and regrowth [PDF]
MR Kritzik+6 more
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Binding Selectivity Analysis from Alchemical Receptor Hopping and Swapping Free Energy Calculations [PDF]
We present receptor hopping and receptor swapping free energy estimation protocols based on the Alchemical Transfer Method (ATM) to model the binding selectivity of a set of ligands to two arbitrary receptors. The receptor hopping protocol, where a ligand is alchemically transferred from one receptor to another in one simulation, directly yields the ...
arxiv
Insights on the Functional Interaction between Group 1 Metabotropic Glutamate Receptors (mGluRI) and ErbB Receptors. [PDF]
Ledonne A, Mercuri NB.
europepmc +1 more source
Cell death induced by TNF or serum starvation is independent of ErbB receptor signaling in MCF-7 breast carcinoma cells [PDF]
Mikala Egeblad, Marja J��ttel�
openalex +1 more source
Differential impact of the ERBB receptors EGFR and ERBB2 on the initiation of precursor lesions of pancreatic ductal adenocarcinoma. [PDF]
Meyers N+3 more
europepmc +1 more source
Expression of c‐erbB receptors, heregulin and oestrogen receptor in human breast cell lines [PDF]
Anna deFazio+4 more
openalex +1 more source