Increased activation of ErbB and NFκB signalling pathways in Darier disease affected skin
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Nancy Ernst +2 more
wiley +1 more source
The Neuroimmunome of Hepatitis Patients Associates With Disease Severity
ABSTRACT Hepatitis is a systemic disease marked by neuroimmune dysregulation beyond hepatic inflammation. Using a systems biology approach, we conducted transcriptomic meta‐analyses across in vitro models, liver tissues, and PBMCs from hepatitis virus‐infected patients to identify neuroimmune signatures.
Adriel Leal Nóbile +18 more
wiley +1 more source
Co-Targeting ErbB Receptors and the PI3K/AKT Axis in Androgen-Independent Taxane-Sensitive and Taxane-Resistant Human Prostate Cancer Cells. [PDF]
Adediran S +9 more
europepmc +1 more source
This study investigates the anti‐cancer effects of pterostilbene (PTS), a naturally occurring dietary phytoestrogen, in a rat model of hepatocellular carcinoma (HCC) induced by a choline‐deficient L‐amino acid‐defined (CDAA) diet. Supplementation with PTS significantly reduces liver steatosis and tumor formation.
Cayla Boycott +12 more
wiley +1 more source
Differential Distribution of erbB Receptors in Human Glioblastoma Multiforme: Expression of erbB3 in CD133-Positive Putative Cancer Stem Cells: Erratum [PDF]
openalex +1 more source
This study aimed to investigate the molecular pathways involved in the health benefits of chronic orange juice (OJ) consumption through global transcriptomic approach in peripheral blood mononuclear cells (PBMCs). Healthy volunteers consumed 500 mL of OJ daily for 60 days.
Layanne Nascimento Fraga +6 more
wiley +1 more source
Primary chemotherapy in breast invasive carcinoma: predictive value of the immunohistochemical detection of hormonal receptors, p53, c-erbB-2, MiB1, pS2 and GST pi [PDF]
Gaëtan MacGrogan +6 more
openalex +1 more source
Breast Cancer Brain Metastasis: Bridging Biological Mechanisms to Therapeutic Innovations
Breast cancer brain metastasis (BCBrM) is driven by a multistep metastatic cascade and shaped by dynamic tumor–brain interactions. This review integrates current mechanistic insights, from molecular signaling pathways to immune evasion, and evaluates preclinical models and emerging therapies.
Jing Feng +3 more
wiley +1 more source
Nano‐Mediated Fluorescence Switching for Epidermal Growth Factor Receptor Detection
This study presents Cy3‐AptEGFR@BPNSs, a novel nano‐detector for real‐time, visual monitoring of EGFR expression in cancer cells. Addressing the limitations of current methods, this detector utilises fluorescence quenching/recovery, providing high specificity and sensitivity, with fluorescence intensity proportional to EGFR levels.
Xin Fu +11 more
wiley +1 more source
Uterine Serous Carcinoma Arising From Endometrial Polyp: A Case Report
Serous carcinoma is the prototype of type II endometrial carcinoma. A 71-year-old woman who had history of smoking, diabetes mellitus and hypertension admitted to the hospital with postmenopausal uterine bleeding.
Sibel Bektaş +4 more
doaj

