Results 31 to 40 of about 38,315 (266)

Chinese expert consensus on the diagnosis and treatment of HER2‐altered non–small cell lung cancer

Thoracic Cancer, Volume 14, Issue 1, Page 91-104, January 2023., 2023
To improve the diagnosis and treatment of HER2‐altered non‐small cell lung cancer in China, we reached consensus on detection strategy based on alteration type, sample selection, detection method, quality control, and treatment suggestion. Moreover, we systematically reviewed the clinical efficacy, resistance mechanisms, and development status of HER2‐
Shirong Zhang, Wenxian Wang, Chunwei Xu, Yongchang Zhang, Xiuyu Cai, Qian Wang, Zhengbo Song, Ziming Li, Jinpu Yu, Wenzhao Zhong, Zhijie Wang, Jingjing Liu, Anwen Liu, Wen Li, Ping Zhan, Hongbing Liu, Tangfeng Lv, Liyun Miao, Lingfeng Min, Gen Lin, Long Huang, Jingping Yuan, Zhansheng Jiang, Xingxiang Pu, Chuangzhou Rao, Dongqing Lv, Zongyang Yu, Xiaoyan Li, Chuanhao Tang, Chengzhi Zhou, Junping Zhang, Hui Guo, Qian Chu, Rui Meng, Xuewen Liu, Jingxun Wu, Jin Zhou, Zhengfei Zhu, Weiwei Pan, Xiaowei Dong, Fei Pang, Kai Wang, Chao Yao, Guomin Lin, Site Li, Zhi Yang, Jiancheng Luo, Hongtao Jia, Xiuqing Nie, Liping Wang, Youcai Zhu, Xiao Hu, Yanru Xie, Xinqing Lin, Jing Cai, Yang Xia, Huijing Feng, Lin Wang, Yingying Du, Wang Yao, Xuefei Shi, Xiaomin Niu, Dongmei Yuan, Yanwen Yao, Jing Kang, Jiatao Zhang, Chao Zhang, Wenbin Gao, Jianhui Huang, Yinbin Zhang, Pingli Sun, Hong Wang, Mingxiang Ye, Dong Wang, Zhaofeng Wang, Bing Wan, Donglai Lv, Genhua Yu, Lin Shi, Yuanli Xia, Feng Gao, Xiaochen Zhang, Tao Xu, Wei Zhou, Haixia Wang, Zhefeng Liu, Nong Yang, Lin Wu, Qiming Wang, Guansong Wang, Zhuan Hong, Jiandong Wang, Meiyu Fang, Yong Fang, Yiping Zhang, Yong Song, Shenglin Ma, Wenfeng Fang, Yuanzhi Lu   +98 more
wiley   +1 more source

mGluR1-Dependent Long Term Depression in Rodent Midbrain Dopamine Neurons Is Regulated by Neuregulin 1/ErbB Signaling

Frontiers in Molecular Neuroscience, 2018
Increasing evidence demonstrates that the neurotrophic factor Neuregulin 1 (NRG1) and its receptors, ErbB tyrosine kinases, modulate midbrain dopamine (DA) transmission.
Ada Ledonne, Nicola Biagio Mercuri, Nicola Biagio Mercuri   +2 more
doaj   +1 more source

EGFR Signaling in Lung Fibrosis

Cells, 2022
In this review article, we will first provide a brief overview of the ErbB receptor–ligand system and its importance in developmental and physiological processes.
Fabian Schramm, Liliana Schaefer, Malgorzata Wygrecka   +2 more
doaj   +1 more source

ErbB Receptors and ErbB Targeted Therapies in Endometrial Cancer

Journal of Cancer Therapy, 2014
The Epidermal Growth Factor system is present in human organs and plays an important role in cell proliferation, differentiation and apoptosis during embryogenesis and postnatal development. It has four receptors (EGFR, ErbB-2, ErbB-3 and ErbB-4) and numerous ligands.
Androutsopoulos Georgios, Michail Georgios, Adonakis Georgios, Decavalas Georgios   +3 more
openaire   +4 more sources

Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis. [PDF]

PLoS ONE, 2010
The Lrig genes encode a family of transmembrane proteins that have been implicated in tumorigenesis, psoriasis, neural crest development, and complex tissue morphogenesis. Whether these diverse phenotypes reflect a single underlying cellular mechanism is
Victoria E Abraira, Takunori Satoh, Donna M Fekete, Lisa V Goodrich   +3 more
doaj   +1 more source

The effects of FTO gene rs9939609 polymorphism on the association between breast cancer and dietary intake

Journal of Cellular and Molecular Medicine, Volume 26, Issue 23, Page 5794-5806, December 2022., 2022
Abstract Breast cancer (BC) is the leading cause of cancer‐related deaths in females worldwide and is related to genetic and environmental factors. Dietary components may strongly influence the risk of BC. A possible association was also reported between the fat mass and obesity‐associated (FTO) single‐nucleotide polymorphisms (SNPs) and BC. This study
Saeid Doaei, Sepideh Abdollahi, Golsa Khalatbari Mohseni, Maryam Gholamalizadeh, Mohammad Esmail Akbari, Seyed Mohammad Poorhosseini, Seyedeh Elaheh Bagheri, Soudeh Ghafouri‐Fard, Ghasem Azizi Tabesh, Alireza Moslem, Naeemeh Hasanpour Ardekanizadeh, Saeed Omidi, Azita Hekmatdoost, Mahdi Alam Rajabi, Seyed Alireza Mosavi Jarrahi, Mark O. Goodarzi   +15 more
wiley   +1 more source

Phosphotyrosine interactome of the ErbB‐receptor kinase family [PDF]

Molecular Systems Biology, 2005
Interactions between short modified peptide motifs and modular protein domains are central events in cell signal-transduction. We determined interaction partners to all cytosolic tyrosine residues of the four members of the ErbB-receptor family in an unbiased fashion by quantitative proteomics using pull-down experiments with pairs of phosphorylated ...
Schulze, W. X., Deng, L., Mann, Matthias
openaire   +4 more sources

The Dumb ErbB Receptor Helps Healing [PDF]

Journal of Investigative Dermatology, 2007
ErbB3 receptor is a member of the epidermal growth factor (EGF) receptor (ErbB1) family. Okwueze et al. have transfected this receptor in a pig model of wounds and demonstrate that it accelerates the resurfacing of the wounds when combined with epiregulin or heparin-binding EGF. Currently, only hypotheses can be proposed to explain the observations.
openaire   +4 more sources

The interactome of human EGF/ErbB receptors [PDF]

Molecular Systems Biology, 2006
Mol Syst Biol. 2: 2006.0006 When you search PubMed for ‘EGF receptor’ (EGFR), the database returns more than 5000 hits. This is not entirely surprising given the receptor's eminent role in cancer biology. However, it is truly surprising that two recent papers published by the groups of Gavin MacBeath and Matthias Mann add a whole new dimension to the ...
Peter Uetz, Igor Stagljar
openaire   +2 more sources

Targeting the Calmodulin-Regulated ErbB/Grb7 Signaling Axis in Cancer Therapy

Journal of Pharmacy & Pharmaceutical Sciences, 2013
Signal transduction pathways essential for the survival and viability of the cell and that frequently present aberrant expression or function in tumors are attractive targets for pharmacological intervention in human cancers. In this short review we will
Antonio Villalobo, Irene García-Palmero, Silviya R. Stateva, Karim Jellali   +3 more
doaj   +1 more source