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Erenumab: First Global Approval
Drugs, 2018Amgen and Novartis are developing erenumab (AIMOVIG™, erenumab-aooe)-a fully human monoclonal antibody calcitonin gene-related peptide (CGRP) receptor antagonist-for the prevention of migraine. CGRP is a vasodilatory neuropeptide implicated in the pathophysiology of migraine and treatment with erenumab was associated with significant reductions in ...
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Erenumab for episodic migraine prophylaxis
Expert Review of Neurotherapeutics, 2019Introduction: This paper reviews placebo-controlled randomized double-blind studies with erenumab for the prevention of migraine. Erenumab is a fully human monoclonal antibody (mAb), which specifically blocks the calcitonin gene-related peptide (GGRP) receptor.
Lucas Hendrik, Overeem +2 more
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Predicting erenumab adverse events with single-cell genomics
Lancet, The, 2020Angeliki Vgontzas, William Renthal
exaly

