Results 101 to 110 of about 6,538 (228)
Estado actual de las resistencias de Candida a los fármacos antifúngidos y estudio de los mecanismos implicados [PDF]
[ES] El género Candida se encuentra taxonómicamente ubicado dentro del reino Fungi,subreino Dikarya y orden Sacharomycetales (Bonifaz, 2012). Se trata de una levadura redonda u ovalada de 4-6 μm de tamaño denominada blastoconidio, que forma gemaciones ...
Bilbao Bilbao, Nagore
core
ABSTRACT This review highlights the integration of drug repurposing and nanotechnology‐driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidiasis, providing a framework for future translational research and clinical application.
Dominique Mesquita e Silva +8 more
wiley +1 more source
Limited ERG11 Mutations Identified in Isolates of Candida auris Directly Contribute to Reduced Azole Susceptibility [PDF]
Multiple Erg11 amino acid substitutions were identified in clinical isolates of Candida auris originating from India and Colombia. Elevated azole MICs were detected in Saccharomyces cerevisiae upon heterologous expression of C.
Kelley R. Healey +6 more
openaire +2 more sources
Doxorubicin induces drug efflux pumps in Candida albicans [PDF]
Candida albicans is one of the most important opportunistic fungal pathogens. It can cause serious fungal diseases in immunocompromised patients, including those with cancer. Treatment failures due to the emergence of drug-resistant C.
Coste, Alix T. +8 more
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Fungicidal versus Fungistatic activity of five Iranian essences against fluconazole resistant Candida species [PDF]
Introduction: Antifungal resistant is one of the causes of high mortality rates during invasive candidiasis. Since development of new antifungal agents is limited, researchers have focused on natural products including essential oils (EOs) with ...
Khosravi, Ali Reza +2 more
core +2 more sources
Characterisation of Antifungal Resistance to Azoles in Colombian Isolates of Malassezia spp.
ABSTRACT Background Malassezia genus includes lipodependent commensal yeasts of humans and animals' skin and mucous membranes. It can cause dermatological pathologies, and azoles are mainly used for treatment. However, in vitro susceptibility testing has shown decreased sensitivity to these antifungals.
Juan Camilo Galvis‐Marín +4 more
wiley +1 more source
The influence of genetic stability on Aspergillus fumigatus virulence and azole resistance [PDF]
Genetic stability is extremely important for the survival of every living organism, and a very complex set of genes has evolved to cope with DNA repair upon DNA damage.
Carmo, Rafaela Andrade do +10 more
core +4 more sources
ABSTRACT Background Antifungal resistance is an expanding and increasingly significant issue representing a global threat for public health. In the last few years, different cases of dermatophytosis infections due to terbinafine‐resistant Trichophyton mentagrophytes have been reported worldwide. In particular, T.
Paolo Gaibani +13 more
wiley +1 more source
Candida auris is an emerging multi-drug resistant pathogen with high mortality rate; nosocomial infections have been reported worldwide, causing a major challenge for clinicians and microbiological laboratories. The study aims to describe new cases of C.
Reem AlJindan +6 more
doaj +1 more source
Clonal Strain Persistence of Candida albicans Isolates from Chronic Mucocutaneous Candidiasis Patients [PDF]
Funding: The study was supported by the MRC for a PhD studentship for AM and the Wellcome Trust for funding (086827, 075470, 097377 & 101873). Acknowledgments We thank Professor Frank Odds for MLST central database curation and useful discussions.Peer ...
Gow, Neil A. R. +4 more
core +2 more sources

