Results 101 to 110 of about 6,538 (228)

Estado actual de las resistencias de Candida a los fármacos antifúngidos y estudio de los mecanismos implicados [PDF]

open access: yes, 2018
[ES] El género Candida se encuentra taxonómicamente ubicado dentro del reino Fungi,subreino Dikarya y orden Sacharomycetales (Bonifaz, 2012). Se trata de una levadura redonda u ovalada de 4-6 μm de tamaño denominada blastoconidio, que forma gemaciones ...
Bilbao Bilbao, Nagore
core  

Statins as Antifungal Agents: A Review on Drug Repurposing and Nanotechnology‐Driven Delivery Strategies

open access: yesFundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.
ABSTRACT This review highlights the integration of drug repurposing and nanotechnology‐driven delivery strategies as innovative approaches to enhance the antifungal activity of statins against mucosal candidiasis, providing a framework for future translational research and clinical application.
Dominique Mesquita e Silva   +8 more
wiley   +1 more source

Limited ERG11 Mutations Identified in Isolates of Candida auris Directly Contribute to Reduced Azole Susceptibility [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2018
Multiple Erg11 amino acid substitutions were identified in clinical isolates of Candida auris originating from India and Colombia. Elevated azole MICs were detected in Saccharomyces cerevisiae upon heterologous expression of C.
Kelley R. Healey   +6 more
openaire   +2 more sources

Doxorubicin induces drug efflux pumps in Candida albicans [PDF]

open access: yes, 2017
Candida albicans is one of the most important opportunistic fungal pathogens. It can cause serious fungal diseases in immunocompromised patients, including those with cancer. Treatment failures due to the emergence of drug-resistant C.
Coste, Alix T.   +8 more
core  

Fungicidal versus Fungistatic activity of five Iranian essences against fluconazole resistant Candida species [PDF]

open access: yes, 2018
Introduction: Antifungal resistant is one of the causes of high mortality rates during invasive candidiasis. Since development of new antifungal agents is limited, researchers have focused on natural products including essential oils (EOs) with ...
Khosravi, Ali Reza   +2 more
core   +2 more sources

Characterisation of Antifungal Resistance to Azoles in Colombian Isolates of Malassezia spp.

open access: yesMycoses, Volume 68, Issue 9, September 2025.
ABSTRACT Background Malassezia genus includes lipodependent commensal yeasts of humans and animals' skin and mucous membranes. It can cause dermatological pathologies, and azoles are mainly used for treatment. However, in vitro susceptibility testing has shown decreased sensitivity to these antifungals.
Juan Camilo Galvis‐Marín   +4 more
wiley   +1 more source

The influence of genetic stability on Aspergillus fumigatus virulence and azole resistance [PDF]

open access: yes, 2018
Genetic stability is extremely important for the survival of every living organism, and a very complex set of genes has evolved to cope with DNA repair upon DNA damage.
Carmo, Rafaela Andrade do   +10 more
core   +4 more sources

Clinical Characteristics and Genomic Analysis of a Trichophyton indotineae Strain Resistant to Terbinafine and Fluconazole Isolated in Italy

open access: yesMycoses, Volume 68, Issue 8, August 2025.
ABSTRACT Background Antifungal resistance is an expanding and increasingly significant issue representing a global threat for public health. In the last few years, different cases of dermatophytosis infections due to terbinafine‐resistant Trichophyton mentagrophytes have been reported worldwide. In particular, T.
Paolo Gaibani   +13 more
wiley   +1 more source

Drug Resistance-Associated Mutations in ERG11 of Multidrug-Resistant Candida auris in a Tertiary Care Hospital of Eastern Saudi Arabia

open access: yesJournal of Fungi, 2020
Candida auris is an emerging multi-drug resistant pathogen with high mortality rate; nosocomial infections have been reported worldwide, causing a major challenge for clinicians and microbiological laboratories. The study aims to describe new cases of C.
Reem AlJindan   +6 more
doaj   +1 more source

Clonal Strain Persistence of Candida albicans Isolates from Chronic Mucocutaneous Candidiasis Patients [PDF]

open access: yes, 2016
Funding: The study was supported by the MRC for a PhD studentship for AM and the Wellcome Trust for funding (086827, 075470, 097377 & 101873). Acknowledgments We thank Professor Frank Odds for MLST central database curation and useful discussions.Peer ...
Gow, Neil A. R.   +4 more
core   +2 more sources

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