Results 91 to 100 of about 6,332 (203)
Synthesis of new imidazole-based ionic liquids with antifungal activity against Candida albicans
Iranian Journal of Microbiology, 2023 Background and Objectives: Candida albicans cause a problematic condition in immunocompromised patients that could not be treated quickly due to the resistant behavior of microorganisms. This study aimed to investigate the effect of a novel ionic liquid
Amir Habibi +4 more
doaj +1 more source
Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae [PDF]
, 2017 Azole-resistant strains of Aspergillus fumigatus have been detected and the underlying molecular mechanisms of resistance characterized. Point mutations in the cyp51A gene have been proved to be related to azole resistance in A.
Alcazar-Fuoli, L. +3 more
core
iMetaMed, Volume 2, Issue 1, March 2026.Oral microbiota: findings, classification, clinical significance, and therapeutic interventions for human systemic diseases ABSTRACT The oral microbiota is an ecological community of commensal, symbiotic, and pathogenic microorganisms that colonizes the oral cavity.
Miao Zhang +13 more
wiley +1 more source
All LifeIntroduction Candida albicans is an opportunistic pathogen linked to severe, often fatal, infections. Azoles are the first line of treatment, but its resistance has increasingly been reported worldwide.
Elisa María Sánchez-Villacreses +5 more
doaj +1 more source
mSphereThe widespread use of azole antifungals in agriculture and clinical settings has led to serious drug resistance. Overexpression of the azole drug target 14α-demethylase ERG11 (CYP51) is the most common fungal resistance mechanism.
Pengju Yu +7 more
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2015 Objective: To investigate the azole susceptibility of Candida albicans (C. albicans) from vulvovaginal candidosis patients and to analyze the relationship between ERG11 gene mutations in these isolates and azole resistance. Methods: Three hundred and two
Bin Wang +8 more
doaj +1 more source
Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients [PDF]
, 2017 Objectives Patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED, APS-I) suffer from chronic candidosis caused mainly by Candida albicans, and repeated courses of azole antifungals have led to the development of resistance ...
Bowyer, Paul +5 more
core
Fungicidal versus Fungistatic activity of five Iranian essences against fluconazole resistant Candida species [PDF]
, 2018 Introduction: Antifungal resistant is one of the causes of high mortality rates during invasive candidiasis. Since development of new antifungal agents is limited, researchers have focused on natural products including essential oils (EOs) with ...
Khosravi, Ali Reza +2 more
core +2 more sources
Structural basis for heterogeneous phenotype of ERG11 dependent Azole resistance in C.albicans clinical isolates [PDF]
SpringerPlus, 2014 Correlating antifungal Azole drug resistance and mis-sense mutations of ERG11 has been paradoxical in pathogenic yeast Candida albicans. Amino acid substitutions (single or multiple) are frequent on ERG11, a membrane bound enzyme of Ergosterol biosynthesis pathway. Presence or absence of mutations can not sufficiently predict susceptibility. To analyze
Debnath, Surajit, Addya, Soma
openaire +2 more sources
Biocide Response of Candida auris
Mycoses, Volume 69, Issue 3, March 2026.ABSTRACT Candida auris is an emerging multidrug‐resistant yeast demonstrating remarkable persistence in healthcare environments, contributing to nosocomial transmission and outbreak persistence. Increasing disinfectant failure reports have raised concerns regarding infection control policies, as environmental reservoirs play central roles in its spread.
Sidre Erganis +3 more
wiley +1 more source