Results 101 to 110 of about 4,848 (182)

Molecular epidemiology and azole resistance mechanism study of Candida guilliermondii from a Chinese surveillance system

Scientific Reports, 2017
We studied the molecular epidemiology and mechanism of azole resistance of 164 C. guilliermondii isolates from a nationwide multi-center surveillance program.
Jing-Wei Cheng, Kang Liao, Timothy Kudinha, Shu-Ying Yu, Meng Xiao, He Wang, Fanrong Kong, Ying-Chun Xu   +7 more
doaj   +1 more source

First report of amphotericin B resistant Candida haemulonii isolated from the ICU of a referral hospital in Indonesia

Iranian Journal of Microbiology
Background and Objectives: Amphotericin B is a broad-spectrum antifungal agent commonly used to treat Candida haemulonii infection. C. haemulonii was isolated from patients reported to be intrinsically resistant to amphotericin B, encoded by the ERG2 ...
Rifdah Hanifah, Mardiastuti Wahid, Andi Yasmon   +2 more
doaj   +1 more source

Investigation of mutations in Erg11 gene of fluconazole resistant Candida albicans isolates from Turkish hospitals

, 2011
P>Widespread use of fluconazole has resulted in resistance in strains of Candida. The aim of our study was to investigate Y132H and other mutations in the ERG11 gene in conferring fluconazole resistance to C. albicans isolates.
Yucesoy, Mine, Ergon, MAHMUT CEM, Manastir, Lerzan   +2 more
core   +1 more source

Identification and analyses of ERG11 gene mutations from fluconazole-susceptible and fluconazole-resistant Candida isolates

, 2011
Por muitos anos o fluconazol tem sido uma opção usual para tratamento de infecções por Candida. Entretanto, o uso indiscriminado desta terapia antimicótica tem favorecido o surgimento de microrganismos resistentes.
Vagner Oliveira Carvalho, Carvalho, Vagner Oliveira   +1 more
core   +1 more source

Harnessing Machine Learning to Uncover Hidden Patterns in Azole-Resistant CYP51/ERG11 Proteins

Microorganisms
Fungal resistance is a public health concern due to the limited availability of antifungal resources and the complexities associated with treating persistent fungal infections. Azoles are thus far the primary line of defense against fungi. Specifically, azoles inhibit the conversion of lanosterol to ergosterol, producing defective sterols and impairing
Otávio Guilherme Gonçalves de Almeida, Marcia Regina von Zeska Kress   +1 more
openaire   +3 more sources

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

[Investigation of ERG11 and MRR1 Resistance Genes in Candida parapsilosis Isolates].

Mikrobiyoloji bulteni
Candida parapsilosis is an important fungal pathogen that is particularly isolated from blood cultures. In recent years, although there are regional differences between centres, resistance to fluconazole which is the most commonly preferred drug for candidemia, has increased in many regions.
Kurt, Ozge, Kuskucu, Mert Ahmet, Yazgan, Zeynep, Arslan, Nese, Aygun, Gokhan, Kucukbasmaci, Omer   +5 more
openaire   +2 more sources

Non-synonymous ERG11 mutations in M. restricta and M. arunalokei: impact on azole susceptibility

Microbiology Spectrum
Malassezia are commensal lipid-dependent yeasts and opportunistic pathogens that cause superficial mycoses and systemic infection. Azole antifungals target cell wall ergosterol synthesis and are the first line of antifungal treatment.
Cheryl Leong, Wisely Chua, Cheng-Shoong Chong, Shi Mun Lee, Sebastian Maurer-Stroh, Won Hee Jung, Thomas L. Dawson   +6 more
doaj   +1 more source

ERG11 gene point mutations in C.krusei clinical isolates.

, 2015
Note: the numbering of the nucleotides shown in table 4 starts with 1 for the A of the ATG start codon. FJ445756, GenBank Accession no. of C.krusei whose ERG11 sequence published online, used to align with our C.krusei clinical isolates in this study ...
Juanxia Meng (703114), Yi Xing (17517), Mingfeng Zhao (703111), Yanyu Jiang (787683), Rimao Wu (787682), Rui Cui (622759), Jinyan Chen (110339), Jianlei Zhang (325264), Yuchen Zhang (524816), Qi Deng (314917), Xiaoyuan He (787681), Jie Chen (5892), Xiaoli Cao (703113), Tao Sui (436563)   +13 more
core   +1 more source

Effect of biogenic selenium nanoparticles on ERG11 and CDR1 gene expression in both fluconazole-resistant and -susceptible Candida albicans isolates

Current Medical Mycology, 2017
Background and Purpose: Candida albicans is the most common Candida species (spp.) isolated from fungal infections. Azole resistance in Candida species has been considerably increased in the last decades.
Nasrin Parsamehr, Sasan Rezaie, Sadegh Khodavaisy, Samira Salari, Sanaz Hadizadeh, Mohammad Kord, Seyed Amin Ayatollahi Mousavi   +6 more
doaj