O factor de trancrição NDT80 como regulator negativo da adesão e da formação de biofilme em Candida parapsilosis [PDF]
Mestrado em Biologia Molecular e CelularC. parapsilosis infections incidence has been increasing for the past 20 years. Its caracteristics of adhering and forming biofilms are a critical factor for infection caused by this organism, affecting from ...
Gomes, Nuno Miguel Araújo da Cunha
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The evolution of drug resistance in clinical isolates of Candida albicans [PDF]
Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with azole inhibitors of ergosterol biosynthesis often leading to drug resistance.
Abbey, Darren A. +13 more
core +1 more source
Mechanism of Action of a Novel Antifungal Compound [PDF]
Opportunistic fungal infections have become problematic in recent years. There has been an emergence of new fungal pathogens, development of antifungal resistance, and increasing prevalence.
Ward, Amber
core +1 more source
Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose. [PDF]
BackgroundUnderstanding how fungi degrade lignocellulose is a cornerstone of improving renewables-based biotechnology, in particular for the production of hydrolytic enzymes.
Archer, David B +20 more
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Candida glabrata : a review of its features and resistance [PDF]
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections.
A Chakrabarti +155 more
core +1 more source
Candida infections, causes, targets and resistance mechanisms. Traditional and alternative antifungal agents [PDF]
The genus Candida includes about 200 different species, but only a few species are human opportunistic pathogens and cause infections when the host becomes debilitated or immunocompromised. Candida infections can be superficial or invasive.
Leonardi, Darío +1 more
core +3 more sources
Molecular mechanisms of azole resistance in Candida bloodstream isolates
Background Antifungal resistance rates are increasing. We investigated the mechanisms of azole resistance of Candida spp. bloodstream isolates obtained from a surveillance study conducted between 2012 and 2015.
Jocelyn Qi-Min Teo +6 more
doaj +1 more source
Tipping the balance both ways: drug resistance and virulence in Candida glabrata [PDF]
Among existing fungal pathogens, Candida glabrata is outstanding in its capacity to rapidly develop resistance to currently used antifungal agents. Resistance to the class of azoles, which are still widely used agents, varies in proportion (from 5 to 20%)
Bolotin-Fukuhara, Monique +2 more
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Drug Resistance in Eukaryotic Microorganisms [PDF]
Eukaryotic microbial pathogens are major contributors to illness and death globally. Although much of their impact can be controlled by drug therapy as with prokaryotic microorganisms, the emergence of drug resistance has threatened these treatment ...
A Abdolrasouli +193 more
core +4 more sources

