Results 131 to 140 of about 3,777 (166)

Advances in vulvovaginal candidiasis research: a comprehensive review from epidemiology, diagnosis, treatment to resistance mechanisms. [PDF]

Front Microbiol
Zhu W, Guo L.
europepmc   +1 more source

The Silent Pandemic: Antifungal Resistance and the Future of Invasive Fungal Disease Management. [PDF]

Microorganisms
Bagga R, Kavanoor Sridhar K.
europepmc   +1 more source

Mechanism of azole resistance in <i>Candida glabrata</i> isolates from India: clinical vs. induced perspectives. [PDF]

J Med Microbiol
Pawar K, Singh A.
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Detection of ERG11 gene in fluconazole resistant urinary candida isolates

Egyptian journal of Immunology, 2022
Candida species resistant to fluconazole and voriconazole were screened for the presence of ERG11gene by polymerase chain reaction (PCR). Also, the association of this gene with the demonstration of Candida virulence factors; biofilm formation, phospholipase and proteinases activities were studied.
Manal, El Said, Hala, Badawi, Doaa, Gamal, Dalia, Salem, Heba, Dahroug, Amira, El-Far   +5 more
openaire   +2 more sources

The Role of ERG11 Point Mutations in the Resistance of Candida albicans to Fluconazole in the Presence of Lactate

Pathogens, 2022
Candidiasis refers to both superficial and deep-tissue fungal infections often caused by Candida albicans. The treatment of choice for these infections is the use of azoles, such as fluconazole (FLC). However, the increased use of antifungal agents has led to the emergence of azole-resistant isolates of C. albicans. Thus, the development of alternative
Anna Krasowska, Daria Derkacz, Zofia Łapińska   +2 more
exaly   +5 more sources

Association of T916C (Y257H) mutation inCandida albicans ERG11with fluconazole resistance

Mycoses, 2012
SummaryRepeated and prolonged use of fluconazole in treating candidosis leads to drug resistance. The aim of this study was to confirm the relationship between T916C (Y257H) mutation inCandida albicans ERG11and fluconazole resistance. We replaced one copy ofERG11withERG11containing the T916C mutation inC.
Jie, Zhao, Yonghao, Xu, Chunyang, Li
openaire   +4 more sources

Cloning and characterization of the lanosterol 14α-demethylase (ERG11) gene in Cryptococcus neoformans

Biochemical and Biophysical Research Communications, 2004
The ergosterol pathway in fungal pathogens is an attractive antimicrobial target because it is unique from the major sterol (cholesterol) producing pathway in humans. Lanosterol 14alpha-demethylase is the target for a major class of antifungals, the azoles. In this study we have isolated the gene for this enzyme from Cryptococcus neoformans.
S G, Revankar, J, Fu, M G, Rinaldi, S L, Kelly, D E, Kelly, D C, Lamb, S M, Keller, B L, Wickes   +7 more
openaire   +2 more sources

Implication of efflux pumps and ERG11 genes in resistance of clinical Trichosporon asahii isolates to fluconazole

Journal of Medical Microbiology, 2021
Introduction. Trichosporon asahii has been recognized as an opportunistic agent having a limited sensitivity to antifungal treatment. Hypothesis/Gap Statement. Molecular mechanisms of azole resistance have been rarely reported for Trichosproron asahii.
S, Abbes, H, Sellami, S, Neji, H, Trabelsi, F, Makni, A, Ayadi   +5 more
openaire   +2 more sources

Upregulation of the ERG11 gene in Candida krusei by azoles.

Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2012
Candida species are the agents of local and systemic opportunistic infections and have become a major cause of morbidity and mortality in the last few decades. Azole resistance in Candida krusei (C. krusei) species appears to be the result of gene alterations in relation to the ergosterol biosynthesis pathway, as well as efflux pumps.
M, Tavakoli, F, Zaini, M, Kordbacheh, M, Safara, R, Raoofian, M, Heidari   +5 more
openaire   +1 more source