Results 71 to 80 of about 5,330 (202)

Kajian Molekuler Resistensi Candida Albicans Terhadap Antifungi [PDF]

, 2014
Candida albicans is one of the species Candida which mostly cause infection in human. Antifungal agent azole, polyene, echinocandin, and flucytosine are commonly used for Candida albicans infection treatment.
Candrasari, D. S. (Damiana)
core   +3 more sources

Phylogenetic and Structural Analysis of Miconazole Susceptibility in Malassezia pachydermatis Isolates From Dogs With Otitis Externa

Veterinary Dermatology, EarlyView.
ABSTRACT Background An increased number of dogs with unresolved yeast otitis externa (OE) after miconazole treatment was observed at a tertiary practice. Hypothesis/Objectives To evaluate miconazole susceptibility in Malassezia pachydermatis isolates from canine OE.
Cole M. Belcher, Clarissa P. Souza, Elyas McGuire, Chien‐Che Hung, Joel D. A. Tyndall, Lois L. Hoyer   +5 more
wiley   +1 more source

The evolution of drug resistance in clinical isolates of Candida albicans [PDF]

, 2013
Candida albicans is both a member of the healthy human microbiome and a major pathogen in immunocompromised individuals. Infections are typically treated with azole inhibitors of ergosterol biosynthesis often leading to drug resistance.
Abbey, Darren A., Berman, Judith, Cuomo, Christina, Delorey, Toni, Ford, Christopher B., Funt, Jason, Guiducci, Candace, Issi, Luca, Li, Bi yu, Martinez, Diego A, Rao, Reeta P, Regev, Aviv, Thompson, Dawn A, White, Theodore C   +13 more
core   +1 more source

Advances in Wine Yeast Autolysis: Biochemical and Molecular Mechanisms, and the Release of Organic Compounds in White and Sparkling Wines—An Updated Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT Wine yeasts play a central role in alcoholic fermentation and significantly contribute to the sensory attributes of wines through cellular autolysis during lees aging (sur lie), especially in white wines. This process releases organic compounds that alter the wine's chemical and sensory profile.
José Ricardo Machado dos Santos, Aniela Pinto Kempka   +1 more
wiley   +1 more source

ERG3 and ERG11 genes are critical for the pathogenesis of Candida albicans during the oral mucosal infection [PDF]

International Journal of Oral Science, 2018
AbstractThe hyphal development of Candida albicans (C. albicans) has been considered as an essential virulent factor for host cell damage. However, the missing link between hyphae and virulence of C. albicans is also been discovered. Here, we identified that the null mutants of ERG3 and ERG11, two key genes in ergosterol biosynthesis pathway, can form ...
Zhou, Yujie, Liao, Min, Zhu, Chengguang, Hu, Yao, Tong, Ting, Peng, Xian, Li, Mingyun, Feng, Mingye, Cheng, Lei, Ren, Biao, Zhou, Xuedong   +10 more
openaire   +2 more sources

Nucleotide substitutions in the Candida albicans ERG11 gene of azole-susceptible and azole-resistant clinical isolates [PDF]

Acta Biochimica Polonica, 2013
One of the mechanisms of Candida albicans resistance to azole drugs used in antifungal therapy relies on increased expression and presence of point mutations in the ERG11 gene that encodes sterol 14α demethylase (14DM), an enzyme which is the primary target for the azole class of antifungals. The aim of the study was to analyze nucleotide substitutions
Ślemp-Migiel, Anna, Rother, Magdalena, Wiczkowski, Andrzej   +2 more
openaire   +4 more sources

Recent trends in molecular diagnostics of yeast infections : from PCR to NGS [PDF]

, 2019
The incidence of opportunistic yeast infections in humans has been increasing over recent years. These infections are difficult to treat and diagnose, in part due to the large number and broad diversity of species that can underlie the infection.
Arastehfar, A, Boekhout, T, Buda De Cesare, G, Butler, G, Dolk, E, Gabaldón, Tony, Hafez, A, Hagen, F, Hovhannisyan, H, Hube, B, Iracane, E, Kostrzewa, M, Lackner, M, Lass-Flörl, C, Llorens, C, Mixão, V, Munro, C, Oliveira-Pacheco, J, OPATHY Consortium, the, Pekmezovic, M, Pérez-Hansen, A, Rodriguez Sánchez, Antonio, Sauer, FM, Sparbier, K, Stavrou, AA, Vaneechoutte, Mario, Vatanshenassan, M   +26 more
core   +2 more sources

Integrated Genomic and Phenotypic Analyses Reveal Convergent Resistance Patterns in Clinical Candida tropicalis Isolates

Mycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background The incidence of Candida tropicalis isolation is increasing in hospital settings. High azole resistance and mortality rates make it a pathogen that requires further analysis. Methods Fourteen azole resistant Candida glabrata clinical isolates were collected from a Lebanese hospital and analysed through whole genome sequencing for ...
Christy Chedraoui, Nour Fattouh, Setrida El Hachem, Tsolaire Sourenian, Louna El Bitar, Lama El Moheb, Anna‐Souraya Sleiman, Ibrahim Bitar, Rola Husni, Roy A. Khalaf   +9 more
wiley   +1 more source

Analysis of CDR1 and MDR1 Gene Expression and ERG11 Substitutions in Clinical Candida tropicalis Isolates from Alexandria, Egypt

Brazilian Journal of Microbiology, 2023
Abstract Introduction Candida tropicalis is a common non-albicans Candida (NAC) species that causes numerous fungal infections. Increasing antifungal resistance to azoles in NAC is becoming a major health problem worldwide; however, in Egypt, almost no data is available regarding fluconazole resistance mechanisms in C ...
Mohammed A. El‐Kholy, Ghada F. Helaly, Ebtisam F. El Ghazzawi, Gamal El-Sawaf, Sherine Shawky   +4 more
openaire   +2 more sources

Visible Photosensitizing Disinfectant Spray for Combating Multidrug‐Resistant Candidozyma Auris in Healthcare Settings

Exploration, Volume 6, Issue 2, April 2026.
We designed and synthesized a dual‐type AIE photosensitizer (named TB) spray, containing a cationic quaternary ammonium unit and a glycosyl‐targeted boronic acid moiety, characterized for the elimination of biofilm infections of Candidozyma auris (C. auris) on high‐touch surfaces.
Xiaoyu Xu, Ming‐Yu Wu, Baoping Li, Jie Li, Siyu Chen, Luojia Chen, Donghu Yu, Liupiaopiao Yang, Ziyu Hong, Huaqin Pan, Wei Xiang, Shun Feng, Jong Seung Kim, Lianrong Wang, Zhiqiang Li, Shi Chen, Meijia Gu   +16 more
wiley   +1 more source