Results 81 to 90 of about 3,364 (161)

Comparative Analysis of Two Candida parapsilosis Isolates Originating from the Same Patient Harbouring the Y132F and R398I Mutations in the ERG11 Gene. [PDF]

Cells, 2023
Štefánek M, Garaiová M, Valček A, Jordao L, Bujdáková H.   +4 more
europepmc   +1 more source

Essential gene identification and drug target prioritization in Aspergillus fumigatus.

PLoS Pathogens, 2007
Aspergillus fumigatus is the most prevalent airborne filamentous fungal pathogen in humans, causing severe and often fatal invasive infections in immunocompromised patients.
Wenqi Hu, Susan Sillaots, Sebastien Lemieux, John Davison, Sarah Kauffman, Anouk Breton, Annie Linteau, Chunlin Xin, Joel Bowman, Jeff Becker, Bo Jiang, Terry Roemer   +11 more
doaj   +1 more source

Fluconazole susceptibility and ERG11 gene expression in vaginal candida species isolated from Lagos Nigeria.

International journal of molecular epidemiology and genetics, 2012
Fluconazole resistance is an important type of resistance in Candida because in most countries, fluconazole is the drug of choice for vulvovaginal candidiasis. Candida species resist fluconazole by various mechanisms but there is paucity of data on these in our environment.
Pam, Victoria K, Akpan, Juliet U, Oduyebo, Oyinlola O, Nwaokorie, Francisca O, Fowora, Muinah A, Oladele, Rita O, Ogunsola, Folasade T, Smith, Stella I   +7 more
openaire   +2 more sources

Molecular analysis of ERG11 gene in azole resistant Candida Species among immunocompromised patients

Journal of Medical Mycology
Abstract Background: Candida species are opportunistic pathogens that can cause life-threatening infections, especially in immunocompromised patients. Azole antifungals are widely used for treatment, but resistance is increasing and often due to mutations in the ...
Amal H. Salem, Mervat E. Mashaly, Douaa R. El-deeb, Salah A. Agha, Marwa Eldegwi, Mohammed Elshaer   +5 more
openaire   +1 more source

Genetic prevalence of antifungal resistance gene in cancer patients with Oropharyngeal Candidiasis from Iraq.

مجلة بغداد للعلوم
As the population of immunocompromised patients grew, yeast infections became more common. There has been a significant rate of morbidity and mortality among patients with Candidiasis demonstrating increased resistance to antifungal medications.
Muhamed Abd ulrahman Majeed , Abdulameer Jasim Mohammed , Omar Sadik Shalal   +2 more
doaj   +1 more source

Universal PCR assays to detect Candida FKS and ERG11 mutations

International Journal of Infectious Diseases
Introduction: The emergence of antifungal resistance in Candida species presents significant challenges in managing infections, particularly among immunocompromised patients.
Dr Yuk Yam Cheung, Mr. Zhi Hao ZHANG, Ms. Wing Yan CHAR, Mr. Tsun Hang FONG, Mr. Chun Yu LI   +4 more
doaj   +1 more source

Similarities and distinctions in the activation of the Candida glabrata Pdr1 regulatory pathway by azole and non-azole drugs

mSphere
Incidences of fluconazole (FLC) resistance among Candida glabrata clinical isolates are a growing issue in clinics. The pleiotropic drug response network in C.
Thomas P. Conway, Bao Gia Vu, Sarah R. Beattie, Damian J. Krysan, W. Scott Moye-Rowley   +4 more
doaj   +1 more source

Detection of ERG11 point mutations in iranian fluconazole-resistant Candida albicans isolates

Current Medical Mycology, 2019
Background and Purpose: Candidiasis is referred to a group of superficial and deep-tissue fungal infections often caused by Candida albicans. The superficial infections affect the oral, oropharynx, esophagus, and vaginal mucosa.
Ali Sardari, Hossein Zarrinfar, Rasoul Mohammadi   +2 more
doaj  

Detection of ERG11 gene mutation in coding and non-coding regions of clinical Candida glabrata (Nakaseomyces glabratus) isolates from Pakistan. [PDF]

Access Microbiol
Memon S, Ghanchi NK, Zafar U, Farooqi J, Zaka S, Jabeen K.   +5 more
europepmc   +1 more source