Results 101 to 110 of about 5,330 (202)

Molecular mechanisms of azole resistance in Candida bloodstream isolates

open access: yesBMC Infectious Diseases, 2019
Background Antifungal resistance rates are increasing. We investigated the mechanisms of azole resistance of Candida spp. bloodstream isolates obtained from a surveillance study conducted between 2012 and 2015.
Jocelyn Qi-Min Teo   +6 more
doaj   +1 more source

Emerging Threats in Antifungal-Resistant Fungal Pathogens. [PDF]

open access: yes, 2016
The use of antifungal drugs in the therapy of fungal diseases can lead to the development of antifungal resistance. Resistance has been described for virtually all antifungal agents in diverse pathogens, including Candida and Aspergillus species.
Sanglard, D.
core   +2 more sources

Fungicidal versus Fungistatic activity of five Iranian essences against fluconazole resistant Candida species [PDF]

open access: yes, 2018
Introduction: Antifungal resistant is one of the causes of high mortality rates during invasive candidiasis. Since development of new antifungal agents is limited, researchers have focused on natural products including essential oils (EOs) with ...
Khosravi, Ali Reza   +2 more
core   +2 more sources

Candida glabrata : a review of its features and resistance [PDF]

open access: yes, 2014
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections.
A Chakrabarti   +155 more
core   +1 more source

Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance [PDF]

open access: yes, 2018
Candida auris has emerged as a significant global nosocomial pathogen. This is primarily due to its antifungal resistance profile but also its capacity to form adherent biofilm communities on a range of clinically important substrates.
Ben-Ami   +63 more
core   +4 more sources

Basal expression of ERG11, MDR1 and CDR1 genes in clinical isolates of Candida albicans from Ecuador: insights into azole resistance surveillance

open access: yesAll Life
Introduction Candida albicans is an opportunistic pathogen linked to severe, often fatal, infections. Azoles are the first line of treatment, but its resistance has increasingly been reported worldwide.
Elisa María Sánchez-Villacreses   +5 more
doaj   +1 more source

Succession of physiological stages hallmarks the transcriptomic response of the fungus Aspergillus niger to lignocellulose. [PDF]

open access: yes, 2020
BackgroundUnderstanding how fungi degrade lignocellulose is a cornerstone of improving renewables-based biotechnology, in particular for the production of hydrolytic enzymes.
Archer, David B   +20 more
core  

Drug Resistance in Eukaryotic Microorganisms [PDF]

open access: yes, 2016
Eukaryotic microbial pathogens are major contributors to illness and death globally. Although much of their impact can be controlled by drug therapy as with prokaryotic microorganisms, the emergence of drug resistance has threatened these treatment ...
A Abdolrasouli   +193 more
core   +4 more sources

Molecular biological characteristics of Candida albicans strains causing recurrent vulvovaginal candidiasis with different susceptibility to antifungal drugs in vitro [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия
Objective. To determine molecular biological characteristics of Candida albicans strains from patients with recurrent vulvovaginal candidiasis (RVVC) associated with the formation of resistance to azole drugs. Materials and Methods.
Venchakova V.V.   +11 more
doaj   +1 more source

Fluconazole susceptibility and ERG11 gene expression in vaginal candida species isolated from Lagos Nigeria.

open access: yesInternational journal of molecular epidemiology and genetics, 2012
Fluconazole resistance is an important type of resistance in Candida because in most countries, fluconazole is the drug of choice for vulvovaginal candidiasis. Candida species resist fluconazole by various mechanisms but there is paucity of data on these in our environment.
Pam, Victoria K   +7 more
openaire   +2 more sources

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