Results 31 to 40 of about 974 (83)

Genome-wide association study-identified novel genetic loci for QT interval in Taiwan: implications for population-specific arrhythmia risk. [PDF]

Europace
Huang PS, Li GW, Cheng JF, Chen JJ, Ho LT, Lin TT, Chiu FC, Wu CK, Chang SN, Chuang EY, Wang YC, Tsai CT.   +11 more
europepmc   +1 more source

Delayed Repolarization Caused by hERG Block With Different Drug Modalities Can Be Detected in Stem Cell-Derived Cardiomyocytes: Incubation Time Matters. [PDF]

Clin Transl Sci
Qu Y, Guo W, Wu B, Cui J, Gao B, Nichols JV, Vargas HM.   +6 more
europepmc   +1 more source

hERG Channel Blockade and Antagonistic Interactions of Three Steroidal Alkaloids from <i>Fritillaria</i> Species. [PDF]

Molecules
Lu H, Hao T, Zhang Z, Jiang C, Xu J, Stalin A, Zhao W.   +6 more
europepmc   +1 more source

Amiodarone irrecoverably impairs the function of human ether-a-go-go-related gene potassium channels. [PDF]

Mol Pharmacol
Gelman I, Li W, Guo J, Bogart-Cherry R, Tomei N, Sharma N, Pan A, Yang T, Baranchuk A, El-Diasty M, Zhang S.   +10 more
europepmc   +1 more source

Quantifying Risk of Delayed QT Prolongation of Ipatasertib in Preclinical and Clinical Studies in Cancer Patients. [PDF]

Clin Transl Sci
Poon V, Sutaria D, Prell R, Halpern W, Wong L, Harris A, Wilkins J, Yoshida K, Sane R.   +8 more
europepmc   +1 more source

SPARC: a structural pathogenicity algorithm for risk classification of hERG variants. [PDF]

Europace
Chatelain FC, de Oliveira BR, Grataloup G, Robert N, Alameh M, Thollet A, Montnach J, Feliciangeli S, Rio A, Bibault F, Bichet D, Bignucolo O, Extramiana F, Majumder R, Schott JJ, Probst V, Denjoy I, Lesage F, Loussouarn G, De Waard M.   +19 more
europepmc   +1 more source

Whole exome sequencing identifies KCNH7 variants associated with epilepsy in children. [PDF]

Genes Dis
Wu F, Ji X, Shen M, Cheng P, Feng S, Gao Y, Liu W, Chen J, Li S, Zhang X, Chen Q.   +10 more
europepmc   +1 more source

Locking hERG channels into place: Using photoreactive unnatural amino acids to study voltage gating. [PDF]

Biophys J
Miller JM, Carlson AE.
europepmc   +1 more source

High-throughput screens identify genotype-specific therapeutics for channelopathies. [PDF]

JCI Insight
Egly CL, Shen A, Do TQ, Tellet Cabiya C, Ritschel PA, Woo S, Ku M, Delisle BP, Kroncke BM, Knollmann BC.   +9 more
europepmc   +1 more source

Toxicity of fentanyl (CAS: 437-38-7) and valerylfentanyl (CAS: 122882-90-0): the first integrative in silico toxicology study with clinical and forensic implications. [PDF]

Arch Toxicol
Niżnik Ł, Fijałkowska O, Jurowski K.
europepmc   +1 more source