Results 21 to 30 of about 974 (83)

Chlorpromazine inhibits EAG1 channels by altering the interdomain coupling. [PDF]

Biophys J
Kihn K, Wang ZJ, Chen X, Ghorbani M, Tiwari PB, Klauda JB, Brelidze TI.   +6 more
europepmc   +1 more source

Quantitative analysis of trafficking defects induced by heterozygous expression of hERG voltage sensor domain variants. [PDF]

Channels (Austin)
Zhang Y, Carr J, Hancox JC, Harmer SC, Dempsey CE.   +4 more
europepmc   +1 more source

Discovery of a novel broad-spectrum inhibitor against influenza virus A. [PDF]

Virol J
Yu R, Li P, Shen R, Fei W.
europepmc   +1 more source

KCNH2-L693P Causes Long QT Syndrome Type 2 Through hERG Channel Dysfunction: Functional Validation of a Variant of Uncertain Significance. [PDF]

Mol Genet Genomic Med
Zheng XF, Chen Q, Lu XT, Dai HL, Guang XF.   +4 more
europepmc   +1 more source

Purkinje cell hyperexcitability and depressive-like behavior in mice lacking erg3 (ether-à-go-go-related gene) K⁺ channel subunits. [PDF]

Sci Adv
Schwarz JR, Freitag S, Pechmann Y, Hermans-Borgmeyer I, Wagner W, Wagner W, Hornig S, Kneussel M.   +7 more
europepmc   +1 more source

Activation of Kv11.1 potassium channel suppresses non-small cell lung cancer growth by promoting c-Myc degradation. [PDF]

Commun Biol
Eskandari N, Delisi D, O'Neil R, Bocchetta M, Gentile S.   +4 more
europepmc   +1 more source

Sudden death-associated KCNH2 variants exert opposing effects on a nuclear subdomain of the cardiac potassium channel hERG1. [PDF]

J Biol Chem
Sanchez-Conde FG, Goodrich MR, Stack OM, Goldberg LNR, Ruzycki PK, Jain A, Jimenez-Vazquez EN, Jones DK.   +7 more
europepmc   +1 more source

Targeted nanodelivery strategies for atrial fibrillation: concomitant targeting of fibrosis suppression and electrical conduction restoration through advanced nanobiotechnology. [PDF]

J Nanobiotechnology
Liang Y, Zheng H, Tian Y.
europepmc   +1 more source

An Integrated Nonclinical and Clinical Risk Assessment of the Effects of Investigational ATRi Tuvusertib on QTc Interval in Patients With Solid Tumors. [PDF]

Clin Transl Sci
Mukker JK, Yap TA, Tolcher AW, de Bono JS, Plummer R, Grosser G, van Amsterdam C, Schieferstein H, Witjes H, Diderichsen PM, Krebs-Brown A, Gao W, Strotmann R, Szucs Z, Gounaris I, Venkatakrishnan K.   +15 more
europepmc   +1 more source

Identification and functional assessment of a KCNH2 compound heterozygosity in a patient with presumed idiopathic ventricular fibrillation ascertains the diagnosis of long QT syndrome type 2. [PDF]

Europace
Janková N, Král M, Švecová O, Zídková J, Lietava S, Sladeček S, Pacherník J, Pásek M, Novotný T, Bébarová M.   +9 more
europepmc   +1 more source