Results 1 to 10 of about 576 (123)

Biological studies of clavine alkaloids targeting CNS receptors [PDF]

open access: yesFrontiers in Psychiatry, 2023
In contrast to well established psychedelics such as lysergic acid diethylamide (LSD) and psilocybin, ergot alkaloids of the clavine subclass have not been thoroughly investigated, in spite of their broad occurrence in nature and their well-established ...
Nikhil R. Tasker   +2 more
doaj   +2 more sources

Psychedelic Drugs Rediscovered—In Silico Study of Potential Fetal Exposure to Analogues of Psychedelic Drugs During Pregnancy [PDF]

open access: yesMolecules
A total of 250 known and novel compounds—ketamine and serotonergic psychedelics or their analogues—designed to target depression, addictions and/or other mental or neurological disorders and developed as “recreational” (illegal) drugs from three chemical
Anna W. Sobańska   +2 more
doaj   +2 more sources

Psychedelics: A new era of treatment? [PDF]

open access: yesEuropean Psychiatry, 2021
Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj   +2 more sources

Galactorrhea: how to address this unusual complication after augmentation mammoplasty [PDF]

open access: yesRevista Brasileira de Cirurgia Plástica, 2016
INTRODUCTION: Galactorrhea and galactocele formation after breast augmentation are complications reported in the literature, but the cause remains unknown.
Adriana Sayuri Kurogi Ascenço   +4 more
doaj   +1 more source

High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines. [PDF]

open access: yesPLoS Genetics, 2016
Invasive infections by fungal pathogens cause more deaths than malaria worldwide. We found the ergoline compound NGx04 in an antifungal screen, with selectivity over mammalian cells.
Ireos Filipuzzi   +13 more
doaj   +1 more source

Ropinirole, a Non‐Ergoline Dopamine Agonist [PDF]

open access: yesCNS Drug Reviews, 2005
ABSTRACTDopamine agonists have become indispensable in the treatment of Parkinson's disease. In every‐day practice, however, the decision to select the best compound for an individual patient is rendered difficult because of the large number of substances available on the market.
Wolfgang H, Jost, Dieter, Angersbach
openaire   +2 more sources

Monitoring Surface Defects Deformations and Displacements in Hot Steel Using Magnetic Induction Tomography

open access: yesSensors, 2019
Magnetic Induction Tomography (MIT) is a non-invasive imaging technique that has been widely applied for imaging materials with high electrical conductivity contrasts.
Fang Li   +3 more
doaj   +1 more source

Pleuropulmonary changes induced by ergoline drugs [PDF]

open access: yesEuropean Respiratory Journal, 1996
Classic ergolines, such as bromocriptine, methysergide and ergotamine, can induce chronic pleuropneumonitis. We present the cases of eight patients who developed similar changes whilst on other ergolines. In this retrospective case study spanning 1985-1995, clinical data, radiological material, pulmonary function, bronchoalveolar lavage and ...
P, Pfitzenmeyer   +7 more
openaire   +2 more sources

Differential in Vitro Activation Profiles for Psychedelic versus Non-psychedelic Ergolines at the 5-HT2A Receptor

open access: yesEmerging Trends in Drugs, Addictions, and Health
Introduction: Serotonergic psychedelics induce their characteristic subjective effects via activation of the serotonin 2A receptor (5-HT2AR). This structurally diverse class of drugs includes ergolines (e.g., LSD), phenethylamines (e.g., mescaline), and ...
E. Pottie   +3 more
doaj   +1 more source

Genetics of ergoline alkaloid formation in Penicillium roquefortii [PDF]

open access: yesApplied and Environmental Microbiology, 1985
Auxotrophic, spore color, and alkaloid biosynthetic mutants of Penicillium roquefortii were selected after N-methyl-N'-nitro-N-nitrosoguanidine treatment. Diploids were obtained via protoplast fusion techniques, and the segregants from a diploid were genetically analyzed. The data demonstrated the potential of parasexual recombination in this organism.
S L, Hong, J E, Robbers
openaire   +2 more sources

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