Results 1 to 10 of about 1,329 (197)
High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines. [PDF]
PLoS Genetics, 2016 Invasive infections by fungal pathogens cause more deaths than malaria worldwide. We found the ergoline compound NGx04 in an antifungal screen, with selectivity over mammalian cells.
Ireos Filipuzzi +13 more
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Synthetic Strategies toward Lysergic Acid Diethylamide: Ergoline Synthesis via α-Arylation, Borrowing Hydrogen Alkylation, and C-H Insertion. [PDF]
J Org Chem, 2023 Lysergic acid diethylamide (LSD), a semisynthetic ergoline alkaloid analogue and hallucinogen, is a potent psychoplastogen with promising therapeutic potential.
Tuck JR, Dunlap LE, Olson DE.
europepmc +6 more sources
Biological studies of clavine alkaloids targeting CNS receptors [PDF]
Frontiers in Psychiatry, 2023 In contrast to well established psychedelics such as lysergic acid diethylamide (LSD) and psilocybin, ergot alkaloids of the clavine subclass have not been thoroughly investigated, in spite of their broad occurrence in nature and their well-established ...
Nikhil R. Tasker +2 more
doaj +2 more sources
Ropinirole, a Non‐Ergoline Dopamine Agonist [PDF]
CNS Drug Reviews, 2005 ABSTRACTDopamine agonists have become indispensable in the treatment of Parkinson's disease. In every‐day practice, however, the decision to select the best compound for an individual patient is rendered difficult because of the large number of substances available on the market.
Wolfgang H. Jost, Dieter Angersbach
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Psychedelics: A new era of treatment? [PDF]
European Psychiatry, 2021 Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj +2 more sources
Pleuropulmonary changes induced by ergoline drugs [PDF]
European Respiratory Journal, 1996 Classic ergolines, such as bromocriptine, methysergide and ergotamine, can induce chronic pleuropneumonitis. We present the cases of eight patients who developed similar changes whilst on other ergolines. In this retrospective case study spanning 1985-1995, clinical data, radiological material, pulmonary function, bronchoalveolar lavage and ...
Pierre Pfitzenmeyer +7 more
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Genetics of ergoline alkaloid formation in Penicillium roquefortii [PDF]
Applied and Environmental Microbiology, 1985 Auxotrophic, spore color, and alkaloid biosynthetic mutants of Penicillium roquefortii were selected after N-methyl-N'-nitro-N-nitrosoguanidine treatment. Diploids were obtained via protoplast fusion techniques, and the segregants from a diploid were genetically analyzed. The data demonstrated the potential of parasexual recombination in this organism.
Shuai Hong, James E. Robbers
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Emerging Trends in Drugs, Addictions, and HealthIntroduction: Serotonergic psychedelics induce their characteristic subjective effects via activation of the serotonin 2A receptor (5-HT2AR). This structurally diverse class of drugs includes ergolines (e.g., LSD), phenethylamines (e.g., mescaline), and ...
E. Pottie +3 more
doaj +2 more sources
Synthesis of 5(10Æ9)abeo-Ergolines
HETEROCYCLES, 1997 Sergio Mantegani +4 more
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Galactorrhea: how to address this unusual complication after augmentation mammoplasty [PDF]
Revista Brasileira de Cirurgia Plástica, 2016 INTRODUCTION: Galactorrhea and galactocele formation after breast augmentation are complications reported in the literature, but the cause remains unknown.
Adriana Sayuri Kurogi Ascenço +4 more
doaj +1 more source