Results 21 to 30 of about 576 (123)

Females exhibit greater cardiac volume reductions with expiratory muscle loading during submaximal exercise compared to males

The Journal of Physiology, EarlyView.
Abstract figure legend Intrathoracic pressure (ITP) manipulation during submaximal exercise reveals load‐ and sex‐specific cardiac volume responses. Inspiratory loading increased oesophageal pressure swings and the work of breathing (Wb) but did not alter stroke volume (SV) or ventricular volumes in males or females.
Sarah A. Angus, Michelle Ottlik, Connor J. Doherty, Benjamin P. Thompson, Jason S. Au, Eric J. Stöhr, Paolo B. Dominelli   +6 more
wiley   +1 more source

Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells

International Journal of Cancer, Volume 158, Issue 10, Page 2641-2649, 15 May 2026.
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange, Emily Dodd, Sharanya Nath, Hannah Bowden, Alastair R. Jordan, Hannah Tweddle, Ann Hedley, Ifeoma Chukwuma, Ian Hickson, Sweta Sharma Saha   +9 more
wiley   +1 more source

Feasibility and Potential Effects of Exercise Training Combining Eccentric and Concentric Cycling in Patients With Breast Cancer

European Journal of Sport Science, Volume 26, Issue 4, April 2026.
ABSTRACT Breast cancer treatment impairs aerobic and neuromuscular capacities, leading to a decrease in quality of life. Exercise may counteract these effects if it is individualized to patient characteristics. This study aimed to assess the feasibility and potential effects of combined concentric and eccentric cycling training on exercise capacity ...
Elyse Hucteau, Thomas J. Hureau, Alexandre Decor, Léo Weltzer, Nabil Kouzkouz, Hervé Bischoff, Laura Somme, Roland Schott, Xavier Pivot, Allan F. Pagano, Joris Mallard   +10 more
wiley   +1 more source

Epigenetic Modulation of the ACE System Underlies the Slow Aerobic Muscle Phenotype and Metabolic Exercise Response

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Weekly moderate‐to‐vigorous activity (≈6 h) induced a marked increase in ACE promoter methylation in exercised knee‐extensor muscle. In combination with the ACE I/D genotype, ACE methylation contributed to ACE gene activity regulation in ways aligning with the slow‐twitch, aerobic muscle phenotype and its metabolic response to endurance exercise ...
Flück Martin, Benedikt Gasser, Giraud Marie‐Noëlle   +2 more
wiley   +1 more source

Functional Training Mitigates Reduced Circulating Indole‐3‐Lactate Levels in Persons With Relapsing–Remitting Multiple Sclerosis

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim Indoles are tryptophan (Trp)‐derived metabolites that are produced by the gut microbiota and may influence the gut‐microbiota‐brain axis in multiple sclerosis (MS). Indole‐3‐lactate (ILA) is reduced in persons with MS and improves MS clinical scores in animal models via its anti‐inflammatory remyelinating properties.
Tiffany Wences Chirino, Frederike Adammek, Sergen Belen, Matteo Winker, Sebastian Proschinger, Annette Rademacher, Marit L. Schlagheck, Alexander Schenk, Marie Kupjetz, David Walzik, Clemens Warnke, Marcel Reuter, Friederike Rosenberger, Tim Meyer, Adrian McCann, Per Magne Ueland, Niklas Joisten, Philipp Zimmer   +17 more
wiley   +1 more source

Peak V̇O2Q${\dot V_{{{\mathrm{O}}_2}{\mathrm{Q}}}}$: A new approach for the interpretation of cardiorespiratory fitness estimates

Experimental Physiology, Volume 111, Issue 3, Page 1454-1465, 1 March 2026.
Abstract There are difficulties with the standardisation of interpretative strategies for peak oxygen uptake (peak V̇O2${\dot V_{{{\mathrm{O}}_2}}}$) related to the quality of reference equations. We aimed to investigate the utility of peak V̇O2Q${\dot V_{{{\mathrm{O}}_2}{\mathrm{Q}}}}$, a novel method reflecting how far a measured value is from the ...
Ben Knox‐Brown, Joshua Barnes, Chris Harding, Jonathan Fuld, Karl P. Sylvester   +4 more
wiley   +1 more source

Breathing technique‐dependent acute cardiopulmonary responses during squats in healthy females

Physiological Reports, Volume 14, Issue 6, March 2026.
Abstract Breath‐holding (BH), including variations of the Valsalva maneuver, is used during resistance exercise to stabilize the trunk and increase intra‐abdominal pressure. However, its hemodynamic and ventilatory effects during low‐to‐moderate intensity strength training in women remain unclear.
Sonja Hummelmann, Maxi Kramer, Ulrich Laufs, Sven Fikenzer, Johannes Lässing, Roberto Falz   +5 more
wiley   +1 more source

Exercise Capacity and Ventilatory Response in Children Who Were Born Preterm, With and Without Bronchopulmonary Dysplasia

Pediatric Pulmonology, Volume 61, Issue 2, February 2026.
ABSTRACT Background Bronchopulmonary dysplasia is one of the most common complications of preterm birth and has lifelong repercussions in respiratory health. Objective To examine lung function and exercise capacity and assess potential differences in exertional respiratory pattern and ventilatory and gas exchange responses in school‐aged children with ...
Eleana Kouroukli, Kosmas Sarafidis, John Tsanakas, Elpis Hatziagorou   +3 more
wiley   +1 more source

Effect of moderate altitude and nocturnal oxygen therapy on cerebrovascular function in patients with COPD: A randomized, crossover trial at 2048 m

Experimental Physiology, Volume 111, Issue 2, Page 527-538, 1 February 2026.
Abstract We investigated whether nocturnal oxygen therapy improves next‐day cerebrovascular function in lowlanders with chronic obstructive pulmonary disease (COPD) staying at moderate altitude. This randomized, placebo‐controlled single‐blind crossover trial was performed in moderate‐to‐severe COPD patients [forced expiratory volume in 1 s (FEV1 ...
Dominic Gilliand, Tsogyal D. Latshang, Sayaka S. Aeschbacher, Fabienne Huber, Deborah Flueck, Mona Lichtblau, Stefanie Ulrich, Elisabeth D. Hasler, Philipp M. Scheiwiller, Julian Müller, Silvia Ulrich, Konrad E. Bloch, Michael Furian   +12 more
wiley   +1 more source

Synthetic Strategies toward Lysergic Acid Diethylamide: Ergoline Synthesis via α-Arylation, Borrowing Hydrogen Alkylation, and C-H Insertion. [PDF]

J Org Chem, 2023
Tuck JR, Dunlap LE, Olson DE.
europepmc   +1 more source