Synthesis, Evaluation, and Characterization of an Ergotamine Imprinted Styrene-Based Polymer for Potential Use as an Ergot Alkaloid Selective Adsorbent [PDF]
, 2021 Alkaloid toxicities negatively impact livestock health and production. To assess alkaloid occurrences, adsorbent technologies may offer effective means to their extraction and isolation from a complex feed matrix.
Kudupoje, Manoj B. +3 more
core +2 more sources
Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]
, 2010 Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica +8 more
core +1 more source
Recreational use, analysis and toxicity of tryptamines [PDF]
, 2015 The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio +3 more
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Synthetic studies on polycyclic indole alkaloids [PDF]
, 2006 The first part of this work details the formal total synthesis of HKI 0231B and the first total synthesis of both demethyl HKI 0231A and demethyl HKI 0231B. The formal synthesis used TBAF as a mild reagent to construct the indole.
Wu, Tao
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Crystal Structure of an LSD-Bound Human Serotonin Receptor [PDF]
, 2017 SummaryThe prototypical hallucinogen LSD acts via serotonin receptors, and here we describe the crystal structure of LSD in complex with the human serotonin receptor 5-HT2B.
Betz, Robin M. +12 more
core +2 more sources
, 2008 dissertationEarlier studies have demonstrated the peroxidase oxidation of the delta8-ergolines agroclavine and elymoclavine to their respective 10-hydroxy-delta9, and other derivatives.
Choong, Tung-Chung.
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Conformational Analysis of the D Ring of Lysergic Acid Amides and its Bioactive Conformation [PDF]
, 1985 1H, 13Cnuclear magnetic resonance data on simple lysergic acid amides and ergopeptines indieate eonsiderable flexibility of the D ring. The actual conformation depends upon the existence (or absence) of intramolecular hydrogen bonding between N6 and the ...
Darko Kocjan +2 more
core +3 more sources
Vertebral arteries do not experience tensile force during manual cervical spine manipulation applied to human cadavers [PDF]
, 2022 Background: The vertebral artery (VA) may be stretched and subsequently damaged during manual cervical spine manipulation. The objective of this study was to measure VA length changes that occur during cervical spine manipulation and to compare these to ...
Edwards, W Brent +3 more
core +1 more source
Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]
, 2018 Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V +15 more
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Impaired physical fitness in pediatric inflammatory bowel disease
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Objective There are only a few studies on physical fitness in pediatric inflammatory bowel disease (PIBD). We compared physical fitness in PIBD patients versus healthy controls and analyzed the role of contributing disease‐ and patient‐related factors.
Saija Kantanen +10 more
wiley +1 more source