Enhancement by prolactin of carcinogen induced mammary cancerigenesis in the male rat. [PDF]
, 1975 Mammary tumours were induced in 3 groups of male Long-Evans rats by a series of 6 fortnightly gastric intubations of 7,12-dimethylbenzanthracene. Two weeks before the initial carcinogen treatment one group of rats was grafted with 3 pituitary homografts ...
Brooks, C. +3 more
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Pituitary surgery for small prolactinomas as an alternative to treatment with dopamine agonists [PDF]
, 2018 Despite the fact that consensus guidelines recommend long-term dopamine agonist (DA) therapy as a first-line approach to the treatment of small prolactinoma, some patients continue to prefer a primary surgical approach.
Andres, Robert +4 more
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Voltage sensitivity of dopamine D2-like receptors [PDF]
, 2011 G protein coupled receptors (GPCRs) mediate a multitude of responses serving hormonal, neurotransmitter, and sensory functions. These receptors are important drug targets; in fact, about 27 % of prescribed drugs are GPCR ligands.
Sahlholm, Kristoffer
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The Design of Potential Anti-Parkinsonian Drugs: What is the Dopaminergic Pharmacophore in Ergot Alkaloids? [PDF]
, 1986 The problem of defining structural similarities between apomorphine and certain ergot alkaloid derivatives, two chemically dissimilar types of drugs having similar pharmacological effects, is addressed by considering the three-dimensional geometry of the
Cannon, Joseph G.
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Intoxicação experimental por Ipomoea carnea subsp. fistulosa em caprinos da Argentina: correlação clínico-patológica, com especial atenção ao sistema nervoso central [PDF]
, 2012 Ipomoea carnea subsp. fistulosa, aguapei or mandiyura, is responsible for lysosomal storage in goats. The shrub contains several alkaloids, mainly swansonine which inhibits lysosomal α-mannosidase and Golgi mannosidase II.
Acosta de Pérez, Ofelia C. +4 more
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Contractile Response of Bovine Lateral Saphenous Vein to Ergotamine Tartrate Exposed to Different Concentrations of Molecularly Imprinted Polymer [PDF]
, 2018 Ergot alkaloids, in their active isomeric form, affect animal health and performance, and adsorbents are used to mitigate toxicities by reducing bioavailability.
Dawson, Karl A. +5 more
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Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD) [PDF]
The ergoline d-lysergic acid diethylamide (LSD) is one of the most potent psychedelic drugs. 1-Acetyl-LSD (ALD-52), a derivative of LSD containing an acetyl group on the indole nitrogen, also produces psychedelic effects in humans and has about the same ...
Brandt, SD +7 more
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MOLECULARLY IMPRINTED POLYMERS SYNTHESIZED AS ADSORBENTS FOR ERGOT ALKALOIDS: CHARACTERIZATION AND \u3cem\u3eIN VITRO\u3c/em\u3e AND \u3cem\u3eEX VIVO\u3c/em\u3e ASSESSMENT OF EFFECTS ON ERGOT ALKALOID BIOAVAILABILITY [PDF]
, 2017 Alkaloid toxicities negatively impact livestock health and production and are of serious economic concern to animal industries. To date, few strategies have been developed to evaluate alkaloid levels in feed or to counteract alkaloid toxicities.
Kudupoje, Manoj B.
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Structure-Activity Relationship and Evaluation of Phenethylamine and Tryptamine Derivatives for Affinity towards 5-Hydroxytryptamine Type 2A Receptor. [PDF]
Biomol Ther (Seoul), 2023 Wang S +5 more
europepmc +1 more source
Chemistry of Indoles carrying a Basic Function. Part 5.1 Some Observations while Constructing an Ergoline Ring by Stobbe Reaction [PDF]
, 1999 István Moldvai +5 more
openalex +1 more source