Pharmacology of novel psychoactive substances [PDF]
This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
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Enhancement by prolactin of carcinogen induced mammary cancerigenesis in the male rat. [PDF]
Mammary tumours were induced in 3 groups of male Long-Evans rats by a series of 6 fortnightly gastric intubations of 7,12-dimethylbenzanthracene. Two weeks before the initial carcinogen treatment one group of rats was grafted with 3 pituitary homografts ...
Brooks, C. +3 more
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The Design of Potential Anti-Parkinsonian Drugs: What is the Dopaminergic Pharmacophore in Ergot Alkaloids? [PDF]
The problem of defining structural similarities between apomorphine and certain ergot alkaloid derivatives, two chemically dissimilar types of drugs having similar pharmacological effects, is addressed by considering the three-dimensional geometry of the
Cannon, Joseph G.
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Contractile Response of Bovine Lateral Saphenous Vein to Ergotamine Tartrate Exposed to Different Concentrations of Molecularly Imprinted Polymer [PDF]
Ergot alkaloids, in their active isomeric form, affect animal health and performance, and adsorbents are used to mitigate toxicities by reducing bioavailability.
Dawson, Karl A. +5 more
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MOLECULARLY IMPRINTED POLYMERS SYNTHESIZED AS ADSORBENTS FOR ERGOT ALKALOIDS: CHARACTERIZATION AND \u3cem\u3eIN VITRO\u3c/em\u3e AND \u3cem\u3eEX VIVO\u3c/em\u3e ASSESSMENT OF EFFECTS ON ERGOT ALKALOID BIOAVAILABILITY [PDF]
Alkaloid toxicities negatively impact livestock health and production and are of serious economic concern to animal industries. To date, few strategies have been developed to evaluate alkaloid levels in feed or to counteract alkaloid toxicities.
Kudupoje, Manoj B.
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Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD) [PDF]
The ergoline d-lysergic acid diethylamide (LSD) is one of the most potent psychedelic drugs. 1-Acetyl-LSD (ALD-52), a derivative of LSD containing an acetyl group on the indole nitrogen, also produces psychedelic effects in humans and has about the same ...
Brandt, SD +7 more
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Chemistry of Indoles carrying a Basic Function. Part 5.1 Some Observations while Constructing an Ergoline Ring by Stobbe Reaction [PDF]
István Moldvai +5 more
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Long term tolerability of high dose ergoline derived dopamine agonist therapy for the treatment of Parkinson's disease [PDF]
Prithiva Navan
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Structure-Activity Relationship and Evaluation of Phenethylamine and Tryptamine Derivatives for Affinity towards 5-Hydroxytryptamine Type 2A Receptor. [PDF]
Wang S +5 more
europepmc +1 more source
Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinson’s disease [PDF]
Maurits E. L. Arbouw +8 more
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