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Ergot alkaloids are novel pharmaceutical and therapeutic agents synthesized in this study using fungal species Penicillium citrinum. To get the maximum yield of ergot alkaloids a statistical process of response surface methodology was employed using ...
Memuna Ghafoor Shahid +9 more
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Introduction to the Toxins Special Issue on Ergot Alkaloids
Ergot alkaloids are among the most relevant natural products in the history of toxins and pharmaceuticals. Until the late 20th century, human and livestock exposure to ergot alkaloids was primarily through ingestion of “ergots,” which are spur-shaped or ...
Christopher L. Schardl
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Fate of Ergot Alkaloids during Laboratory Scale Durum Processing and Pasta Production
The fate of ergot alkaloids during the milling of durum and subsequent production and cooking of pasta was examined. Durum samples containing varying amounts of ergot sclerotia (0.01–0.1% by mass) were milled, and all milling product was analyzed ...
Sheryl A. Tittlemier +5 more
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Ergot alkaloids contribute to virulence in an insect model of invasive aspergillosis
Neosartorya fumigata (Aspergillus fumigatus) is the most common cause of invasive aspergillosis, a frequently fatal lung disease primarily affecting immunocompromised individuals. This opportunistic fungal pathogen produces several classes of specialised
Daniel G. Panaccione +1 more
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Relationships among Ergot Alkaloids, Cytochrome P450 Activity, and Beef Steer Growth
Determining a grazing animal’s susceptibility to ergot alkaloids has been a research topic for decades. Our objective was to determine if the Promega™ P450-Glo assay could be used to indirectly detect ergot alkaloids or their metabolites in urine of ...
Charles F. Rosenkrans, Nicholas S. Ezell
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Global Impact of Ergot Alkaloids
"The Global Impact of Ergot Alkaloids" addresses the very broad topic of ergot alkaloids and the influence that they have on many facets of life. The content in this Special Issue pertains to research studying fungi, plants, livestock, and humans.
James L. Klotz
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DURING the first half of the year 1935 communications appeared from four different laboratories, in three different countries, each describing the discovery and isolation of a new alkaloid from ergot, very different in its properties from those previously known.
M S, Kharasch +3 more
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Derivation of the multiply‐branched ergot alkaloid pathway of fungi
Ergot alkaloids are a large family of fungal specialized metabolites that are important as toxins in agriculture and as the foundation of powerful pharmaceuticals.
Daniel G. Panaccione
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Vasoactive Effects of Acute Ergot Exposure in Sheep
Ergotism is a common and increasing problem in Saskatchewan’s livestock. Chronic exposure to low concentrations of ergot alkaloids is known to cause severe arterial vasoconstriction and gangrene through the activation of adrenergic and serotonergic ...
Rossalin Yonpiam +5 more
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Ergot alkaloids (the sum of individual ergot alkaloids are termed as total alkaloids, TA) are produced by the fungus Claviceps purpurea, which infests cereal grains commonly used as feedstuffs.
Sonja Diers, Sven Dänicke
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