Results 11 to 20 of about 1,516 (155)

Novel Ergot Alkaloids Production from Penicillium citrinum Employing Response Surface Methodology Technique

open access: yesToxins, 2020
Ergot alkaloids are novel pharmaceutical and therapeutic agents synthesized in this study using fungal species Penicillium citrinum. To get the maximum yield of ergot alkaloids a statistical process of response surface methodology was employed using ...
Memuna Ghafoor Shahid   +9 more
doaj   +2 more sources

Introduction to the Toxins Special Issue on Ergot Alkaloids

open access: yesToxins, 2015
Ergot alkaloids are among the most relevant natural products in the history of toxins and pharmaceuticals. Until the late 20th century, human and livestock exposure to ergot alkaloids was primarily through ingestion of “ergots,” which are spur-shaped or ...
Christopher L. Schardl
doaj   +3 more sources

Fate of Ergot Alkaloids during Laboratory Scale Durum Processing and Pasta Production

open access: yesToxins, 2019
The fate of ergot alkaloids during the milling of durum and subsequent production and cooking of pasta was examined. Durum samples containing varying amounts of ergot sclerotia (0.01–0.1% by mass) were milled, and all milling product was analyzed ...
Sheryl A. Tittlemier   +5 more
doaj   +2 more sources

Ergot alkaloids contribute to virulence in an insect model of invasive aspergillosis

open access: yesScientific Reports, 2017
Neosartorya fumigata (Aspergillus fumigatus) is the most common cause of invasive aspergillosis, a frequently fatal lung disease primarily affecting immunocompromised individuals. This opportunistic fungal pathogen produces several classes of specialised
Daniel G. Panaccione   +1 more
doaj   +2 more sources

Relationships among Ergot Alkaloids, Cytochrome P450 Activity, and Beef Steer Growth

open access: yesFrontiers in Chemistry, 2015
Determining a grazing animal’s susceptibility to ergot alkaloids has been a research topic for decades. Our objective was to determine if the Promega™ P450-Glo assay could be used to indirectly detect ergot alkaloids or their metabolites in urine of ...
Charles F. Rosenkrans, Nicholas S. Ezell
doaj   +2 more sources

Global Impact of Ergot Alkaloids

open access: yes, 2022
"The Global Impact of Ergot Alkaloids" addresses the very broad topic of ergot alkaloids and the influence that they have on many facets of life. The content in this Special Issue pertains to research studying fungi, plants, livestock, and humans.
James L. Klotz
core   +2 more sources

The New Ergot Alkaloid [PDF]

open access: yesNature, 1936
DURING the first half of the year 1935 communications appeared from four different laboratories, in three different countries, each describing the discovery and isolation of a new alkaloid from ergot, very different in its properties from those previously known.
M S, Kharasch   +3 more
openaire   +2 more sources

Derivation of the multiply‐branched ergot alkaloid pathway of fungi

open access: yesMicrobial Biotechnology, 2023
Ergot alkaloids are a large family of fungal specialized metabolites that are important as toxins in agriculture and as the foundation of powerful pharmaceuticals.
Daniel G. Panaccione
doaj   +1 more source

Vasoactive Effects of Acute Ergot Exposure in Sheep

open access: yesToxins, 2021
Ergotism is a common and increasing problem in Saskatchewan’s livestock. Chronic exposure to low concentrations of ergot alkaloids is known to cause severe arterial vasoconstriction and gangrene through the activation of adrenergic and serotonergic ...
Rossalin Yonpiam   +5 more
doaj   +1 more source

Effects of Ergot Alkaloids on Liver Function of Piglets as Evaluated by the 13C-Methacetin and 13C-α-Ketoisocaproic Acid Breath Test

open access: yesToxins, 2013
Ergot alkaloids (the sum of individual ergot alkaloids are termed as total alkaloids, TA) are produced by the fungus Claviceps purpurea, which infests cereal grains commonly used as feedstuffs.
Sonja Diers, Sven Dänicke
doaj   +1 more source

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