Results 41 to 50 of about 82,445 (191)
Genetics, Genomics and Evolution of Ergot Alkaloid Diversity
Toxins, 2015 The ergot alkaloid biosynthesis system has become an excellent model to study evolutionary diversification of specialized (secondary) metabolites. This is a very diverse class of alkaloids with various neurotropic activities, produced by fungi in several
Carolyn A. Young +8 more
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Relationships among Ergot Alkaloids, Cytochrome P450 Activity, and Beef Steer Growth
Frontiers in Chemistry, 2015 Determining a grazing animal’s susceptibility to ergot alkaloids has been a research topic for decades. Our objective was to determine if the Promega™ P450-Glo assay could be used to indirectly detect ergot alkaloids or their metabolites in urine of ...
Charles F. Rosenkrans, Nicholas S. Ezell
doaj +1 more source
Ammonization of the R- and S‑Epimers of Ergot Alkaloids to Assess Detoxification Potential
, 2022 Detoxification of ergot-contaminated feed by ammonia would be a practical application, given that ammonia is routinely used in the agriculture industry. To assess the effects of ammonia on ergot alkaloids, natural ergot-contaminated wheat was ammoniated.
Ahmad N. Al-Dissi (13040698) +4 more
core +1 more source
Cyclopropanation of carbon-carbon double bonds in ring d of ergot alkaloids [PDF]
, 2013 Some ergot alkaloid derivatives containing a double bond in ring D have been reacted with diazomethane/palladium diacetate reagent to result in formation of a fused cyclopropane ring.
Incze, Mária +5 more
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Ergot Alkaloid Contents in Hybrid Rye are Reduced by Breeding
Agriculture, 2021 Contamination by ergot caused by the phytopathogenic fungus Claviceps purpurea is a constant threat to the whole rye value chain. Ergot alkaloids (EA) produced within the fungal sclerotia are toxic for humans and animals and are subjected to strict ...
Thomas Miedaner +3 more
doaj +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
Plant, Cell &Environment, EarlyView.ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Determination of principal ergot alkaloids in swine feeding
, 2021 BACKGROUND. Ergot alkaloids are secondary metabolites produced by fungi in the genus Claviceps. They contaminate a large variety of cereals, such as rye, triticale, wheat and barley.
Gámiz-Gracia, Laura +9 more
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Toxins, 2021 In the past centuries consumption of bread made of ergot-infected flour resulted in mass poisonings and miscarriages. The reason was the sclerotia of Claviceps purpurea (Fr.) Tul.—a source of noxious ergot alkaloids (ergotamine and ergovaline).
Aleksander Smakosz +3 more
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American Journal of Pharmaceutical Education, 2006 This manuscript reviews the history and pharmacognosy of ergot, and describes the isolation/preparation, chemistry, pharmacodynamics, and pharmacotherapeutics of the major ergot alkaloids and their derivatives. A brief discussion of the hallucinogenic properties of lysergic acid diethylamide is also featured.
openaire +3 more sources
Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.Essential oils of Argyreia capitiformis and Argyreia nasirii display clearly distinct chemical and biological profiles. A. capitiformis is dominated by sesquiterpene hydrocarbons, particularly (E)‐caryophyllene, and shows cytotoxicity against HepG2, SK‐LU‐1, and MCF‐7 cells. In contrast, A.
Tran Thi Ngoc Hanh +7 more
wiley +1 more source