Results 41 to 50 of about 3,594 (162)
American Journal of Pharmaceutical Education, 2006 This manuscript reviews the history and pharmacognosy of ergot, and describes the isolation/preparation, chemistry, pharmacodynamics, and pharmacotherapeutics of the major ergot alkaloids and their derivatives. A brief discussion of the hallucinogenic properties of lysergic acid diethylamide is also featured.
openaire +3 more sources
The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.Abstract Dihydroergotamine (DHE) prescribing information contains a boxed warning regarding the possibility of serious and/or life‐threatening peripheral ischemia with co‐administration of strong cytochrome P450 3A4 (CYP3A4) inhibitors. The effects of the strong CYP3A4 inhibitor itraconazole on the pharmacokinetics and safety of nasally administered ...
Detlef Albrecht +2 more
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Toxins, 2021 In the past centuries consumption of bread made of ergot-infected flour resulted in mass poisonings and miscarriages. The reason was the sclerotia of Claviceps purpurea (Fr.) Tul.—a source of noxious ergot alkaloids (ergotamine and ergovaline).
Aleksander Smakosz +3 more
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Crop Science, Volume 66, Issue 4, July/August 2026.Abstract Red clover (Trifolium pratense L.) is a widely grown perennial forage legume that supports sustainable livestock production through its high nutritive value and bioactive isoflavones. Future climate change, particularly warming and increased rainfall, may influence forage accumulation and isoflavone concentrations.
Palash Mandal +5 more
wiley +1 more source
Cases of ergotism in livestock and associated ergot alkaloid concentrations in feed
Frontiers in Chemistry, 2015 Ergot-induced disease was known long before Biblical times and has been the root cause for countless human epidemics spanning from the early fourteenth century to the late sixteenth century.
A. Morrie Craig +2 more
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Psychedelics, entactogens and psychoplastogens for depression and related disorders
British Journal of Pharmacology, Volume 183, Issue 14, Page 3897-3919, July 2026.Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
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Toxins, 2018 As contamination with cereal ergot has been increasing in western Canada, this study evaluated impacts of feeding a mycotoxin binder (Biomin® II; BB) on nutrient digestibility, alkaloid recovery in feces, and lamb growth performance.
Kim Stanford +6 more
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European Journal of Neurology, Volume 33, Issue 7, July 2026.In this prospective study of 623 adults with migraine treated with erenumab, baseline serum hs‐CRP and TNF‐α were not associated with treatment response. Serum TNF‐α increased modestly during treatment, but changes did not differ between responders and non‐responders.
William K. Karlsson +6 more
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Biochemical and Genetic Characterization of Ergot Alkaloid Biosynthesis in Aspergillus aspearensis
ToxinsErgot alkaloids derived from lysergic acid have impacted humankind significantly as toxins in agriculture and as the foundations of several pharmaceuticals.
Jessica L. Fuss, Daniel G. Panaccione
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Did the French pregnancy pictogram change antiseizure medication use during pregnancy?
Epilepsia, Volume 67, Issue 6, Page 2864-2874, June 2026.Abstract Objective The aim of this study was to assess the impact of introducing a pregnancy pictogram on medication packaging on the prescription and dispensation of antiseizure medications and on the maternal and neonatal outcomes for women exposed to these medications.
Mélanie Araujo +7 more
wiley +1 more source