Results 61 to 70 of about 1,516 (155)

Wherefore the Magic? The Evolutionary Role of Psilocybin in Nature

open access: yesEcology and Evolution, Volume 16, Issue 4, April 2026.
This study explores the evolutionary role of psilocybin, the psychedelic compound found in Psilocybe mushrooms. We provide the first experimental tests of defence and community‐level evidence for invertebrate responses to psilocybin‐producing fungi, revealing significant negative effects on invertebrate locomotion, development, and survival.
K. J. Matthews Nicholass   +16 more
wiley   +1 more source

Cleaving ergot alkaloids - development of a novel food screening method

open access: yes, 2022
Mycotoxins (toxic compounds formed by fungi) in food and feed have caused problems for mankind since the beginning of time. The group of ergot alkaloids plays a special role in human history.
Kuner, Maximilian
core  

Psychedelic Therapies for Comorbid Major Depressive Disorder and Chronic Pain: A Review of Putative Mechanisms of Action

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Major Depressive Disorder (MDD) and chronic pain are independently debilitating conditions that frequently co‐occur. This comorbidity poses a significant clinical challenge, resulting in greater symptom severity, higher disability, and worse prognosis than either condition alone.
Jordana Kazdan   +2 more
wiley   +1 more source

Ergot Alkaloids and their Hallucinogenic Potential in Morning Glories

open access: yes, 2018
Naturally occurring and semisynthetic ergot alkaloids play a role in health care or as recreational drugs in Western and indigenous Mexican societies.
Eckhard Leistner, Ulrike Steiner
core   +1 more source

Reconstituting the complete biosynthesis of D-lysergic acid in yeast

open access: yesNature Communications, 2022
The ergot alkaloids are a class of natural products known for their pharmacologically privileged molecular structure that are used in the treatment of neurological ailments.
Garrett Wong   +6 more
doaj   +1 more source

Leonurine: A Multifaceted Bioactive Alkaloid—From Pharmacological Mechanisms to Clinical Translation: A Narrative Review

open access: yesHealth Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley   +1 more source

Predicting intrauterine vacuum‐induced postpartum hemorrhage‐control device treatment success

open access: yesPregnancy, Volume 2, Issue 2, March 2026.
Abstract Objective To identify predictors of postpartum hemorrhage (PPH) treatment success with the JADA intrauterine vacuum‐induced hemorrhage‐control device in post‐market settings. Methods We performed a retrospective cohort study of PPH managed using the JADA system across 16 centers in the United States (NCT04995887). Treatment success was defined
Marcela C. Smid   +9 more
wiley   +1 more source

Ergot Alkaloids in Feed for Pekin Ducks: Toxic Effects, Metabolism and Carry Over into Edible Tissues

open access: yesToxins, 2015
Hardened sclerotia (ergots) of Claviceps purpurea contaminate cereal grains and contain toxic ergot alkaloids (EA). Information on EA toxicity in ducks is scarce.
Sven Dänicke
doaj   +1 more source

USING ALTERNATIVE REPRESENTATIONS OF THE RGB COLOR MODEL TO SEPARATE ERGOT SCLEROTIA (CLAVICEPS PURPUREA) FROM THE IMPORTED WHEAT [PDF]

open access: yesScientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2021
Sclerotium of ergot is hard fungal body which contain toxic alkaloids to human and livestock. These alkaloids include ergotamine, ergovaline, ergocornine, ergocryptine, and ergocristine.
Tarek FOUDA, Amina ALBEBANY
doaj  

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana   +4 more
wiley   +1 more source

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