Results 31 to 40 of about 3,594 (162)

Introduction to the Toxins Special Issue on Ergot Alkaloids

open access: yesToxins, 2015
Ergot alkaloids are among the most relevant natural products in the history of toxins and pharmaceuticals. Until the late 20th century, human and livestock exposure to ergot alkaloids was primarily through ingestion of “ergots,” which are spur-shaped or ...
Christopher L. Schardl
doaj   +1 more source

Albert Hofmann's Pioneering Work on Ergot Alkaloids and Its Impact on the Search of Novel Drugs at Sandoz, a Predecessor Company of Novartis: Dedicated to Dr. Albert Hofmann on the occasion of his 100th birthday

open access: yesCHIMIA, 2006
The scientific research on ergot alkaloids is fundamentally related to the work of Dr. Albert Hofmann, who was able to produce, from 1935 onwards, a number of novel and valuable drugs, some of which are still in use today.
Rudolf K.A. Giger, Günter Engel
doaj   +1 more source

Natural Ergot Alkaloids in Ocular Pharmacotherapy: Known Molecules for Novel Nanoparticle-Based Delivery Systems

open access: yesBiomolecules, 2020
Several pharmacological properties are attributed to ergot alkaloids as a result of their antibacterial, antiproliferative, and antioxidant effects.
Iara Baldim   +12 more
doaj   +1 more source

Research progress on the contamination hazards and control of ergot alkaloids

open access: yesZhongguo shipin weisheng zazhi
Ergot alkaloids are a type of alkaloids secondary metabolic produced by Claviceps or Epichloë spp infected with black barley, wheat, rye, rice, corn, oats, and various other gramineous plants. Long-term exposure to ergot alkaloids can result in extensive
WANG Yating   +3 more
doaj   +1 more source

Arterial Responses to Acute Low-Level Ergot Exposure in Hereford Cows

open access: yesFrontiers in Veterinary Science, 2018
Ergot alkaloids are toxic secondary metabolites produced by the fungus Claviceps purpurea that contaminate cereal grains. Current Canadian standards allow 2 to 3 parts per million of ergot alkaloids in animal feed.
Vanessa Elizabeth Cowan   +7 more
doaj   +1 more source

Genetics, Genomics and Evolution of Ergot Alkaloid Diversity

open access: yesToxins, 2015
The ergot alkaloid biosynthesis system has become an excellent model to study evolutionary diversification of specialized (secondary) metabolites. This is a very diverse class of alkaloids with various neurotropic activities, produced by fungi in several
Carolyn A. Young   +8 more
doaj   +1 more source

Relationships among Ergot Alkaloids, Cytochrome P450 Activity, and Beef Steer Growth

open access: yesFrontiers in Chemistry, 2015
Determining a grazing animal’s susceptibility to ergot alkaloids has been a research topic for decades. Our objective was to determine if the Promega™ P450-Glo assay could be used to indirectly detect ergot alkaloids or their metabolites in urine of ...
Charles F. Rosenkrans, Nicholas S. Ezell
doaj   +1 more source

Ergot Alkaloid Contents in Hybrid Rye are Reduced by Breeding

open access: yesAgriculture, 2021
Contamination by ergot caused by the phytopathogenic fungus Claviceps purpurea is a constant threat to the whole rye value chain. Ergot alkaloids (EA) produced within the fungal sclerotia are toxic for humans and animals and are subjected to strict ...
Thomas Miedaner   +3 more
doaj   +1 more source

ACTH suppression and adverse effects of cabergoline in horses with pituitary pars intermedia dysfunction

open access: yesEquine Veterinary Education, Volume 38, Issue 9, Page e622-e630, September 2026.
Summary Background The diagnosis and management of pituitary pars intermedia dysfunction (PPID) in horses includes evaluating abnormal plasma concentrations of adrenocorticotrophic hormone (ACTH). Treatment commonly includes the oral dopamine agonist pergolide mesylate, which suppresses the pathologic overproduction of ACTH.
A. Bracken   +5 more
wiley   +1 more source

Survival and development of potato psyllid (Hemiptera: Triozidae) on Convolvulaceae: Effects of a plant-fungus symbiosis (Periglandula). [PDF]

open access: yesPLoS ONE, 2018
Plant species in the family Solanaceae are the usual hosts of potato psyllid, Bactericera cockerelli (Šulc) (Hemiptera: Psylloidea: Triozidae). However, the psyllid has also been shown to develop on some species of Convolvulaceae (bindweeds and morning ...
Navneet Kaur   +6 more
doaj   +1 more source

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