Results 31 to 40 of about 82,445 (191)

Differentially expressed genes in cotyledon of ewes fed mycotoxins

BMC Genomics, 2020
Background Ergot alkaloids (E+) are mycotoxins produced by the endophytic fungus, Epichloë coenophiala, in tall fescue that are associated with ergotism in animals.
J. L. Britt, R. E. Noorai, S. K. Duckett
doaj   +1 more source

Validation of a New Sensitive Method for the Detection and Quantification of R and S-Epimers of Ergot Alkaloids in Canadian Spring Wheat Utilizing Deuterated Lysergic Acid Diethylamide as an Internal Standard

Toxins, 2021
Ergot sclerotia effect cereal crops intended for consumption. Ergot alkaloids within ergot sclerotia are assessed to ensure contamination is below safety standards established for human and animal health.
Jensen Cherewyk, Taylor Grusie-Ogilvie, Barry Blakley, Ahmad Al-Dissi   +3 more
doaj   +1 more source

Ergot alkaloids contribute to virulence in an insect model of invasive aspergillosis

Scientific Reports, 2017
Neosartorya fumigata (Aspergillus fumigatus) is the most common cause of invasive aspergillosis, a frequently fatal lung disease primarily affecting immunocompromised individuals. This opportunistic fungal pathogen produces several classes of specialised
Daniel G. Panaccione, Stephanie L. Arnold   +1 more
doaj   +1 more source

Analysis of ergot alkaloid gene expression and ergine levels in different parts of Ipomoea asarifolia [PDF]

PeerJ
Background Ergot alkaloids are renowned for their pharmacological significance and were historically attributed to fungal symbioses with cereal crops and grasses.
Yanisa Olaranont, Alyssa B. Stewart, Wisuwat Songnuan, Paweena Traiperm   +3 more
doaj   +2 more sources

Influence of Prolonged Serotonin and Ergovaline Pre-Exposure on Vasoconstriction Ex Vivo

Toxins, 2021
Ergot alkaloid mycotoxins interfere in many functions associated with serotonergic neurotransmitters. Therefore, the objective was to evaluate whether the association of serotonin (5-hydroxytryptamine, 5-HT) and ergot alkaloids during a 24 h pre ...
Eriton E. L. Valente, David L. Harmon, James L. Klotz   +2 more
doaj   +1 more source

Natural Ergot Alkaloids in Ocular Pharmacotherapy: Known Molecules for Novel Nanoparticle-Based Delivery Systems

Biomolecules, 2020
Several pharmacological properties are attributed to ergot alkaloids as a result of their antibacterial, antiproliferative, and antioxidant effects.
Iara Baldim, Wanderley P. Oliveira, Varsha Kadian, Rekha Rao, Nitesh Yadav, Sheefali Mahant, Massimo Lucarini, Alessandra Durazzo, Raquel Da Ana, Raffaele Capasso, Selma B. Souto, Antonello Santini, Eliana B. Souto   +12 more
doaj   +1 more source

Albert Hofmann's Pioneering Work on Ergot Alkaloids and Its Impact on the Search of Novel Drugs at Sandoz, a Predecessor Company of Novartis: Dedicated to Dr. Albert Hofmann on the occasion of his 100th birthday

CHIMIA, 2006
The scientific research on ergot alkaloids is fundamentally related to the work of Dr. Albert Hofmann, who was able to produce, from 1935 onwards, a number of novel and valuable drugs, some of which are still in use today.
Rudolf K.A. Giger, Günter Engel
doaj   +1 more source

Research progress on the contamination hazards and control of ergot alkaloids

Zhongguo shipin weisheng zazhi
Ergot alkaloids are a type of alkaloids secondary metabolic produced by Claviceps or Epichloë spp infected with black barley， wheat， rye， rice， corn， oats， and various other gramineous plants. Long-term exposure to ergot alkaloids can result in extensive
WANG Yating, SUN Xiulan, ZHANG Zixuan, YE Yongli   +3 more
doaj   +1 more source

Arterial Responses to Acute Low-Level Ergot Exposure in Hereford Cows

Frontiers in Veterinary Science, 2018
Ergot alkaloids are toxic secondary metabolites produced by the fungus Claviceps purpurea that contaminate cereal grains. Current Canadian standards allow 2 to 3 parts per million of ergot alkaloids in animal feed.
Vanessa Elizabeth Cowan, Vanessa Elizabeth Cowan, Alex Neumann, John McKinnon, Barry Raymond Blakley, Barry Raymond Blakley, Taylor Jayne Grusie, Jaswant Singh   +7 more
doaj   +1 more source

Ergot alkaloids: synthetic approaches to lysergic acid and clavine alkaloids

, 2017
Ergot alkaloids are among the most important pharmaceuticals and natural toxins. Significant progress has been achieved in recent years on the research of ergot alkaloids. In this review, we re-introduced the history of ergot alkaloids.
Yanxing Jia, Haichao Liu
core   +1 more source