Results 241 to 250 of about 511,445 (325)

Role of the ERK signaling pathway in the actions of psychostimulants

, 2009
Oliet Stéphane
openalex   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Establishing a Non-Surgical Mouse Model of Laryngopharyngeal Reflux Disease: Acid-Induced Epithelial Disruption and Protective Role of N-Acetylcysteine. [PDF]

Cells
Chung YY, Kim B, Lee J, Kwak S, Jung M, Kim YS, Baek SK.   +6 more
europepmc   +1 more source

Phasentrennung von Nukleinsäuren: Mechanismen, Eigenschaften und Anwendungen

Angewandte Chemie, EarlyView.
Jüngste Entdeckungen zeigen, dass einzelsträngige langkettige Nukleinsäuren temperaturinduziert phasentrennen und dabei mikrometergroße Kondensate bilden. Dieser Minireview fasst das aktuelle mechanistische Verständnis dieses Phänomens zusammen, beschreibt Strategien zur gezielten Kontrolle der physikalischen und chemischen Eigenschaften der Kondensate
Weixiang Chen, Johann Fritzen, Andreas Walther   +2 more
wiley   +1 more source

Non-canonical EGFR signaling promotes MAPK-dependent extrusion of epithelial cells. [PDF]

J Cell Sci
Molina P, Daniel M, Hoang T, Wang J, Macara I.   +4 more
europepmc   +1 more source

Bounded Model Checking using SMT Solvers for RKIP Inhibited ERK Pathway Model

Ghosh, Krishnendu, Ball, Jay
openalex   +1 more source

Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications

Angewandte Chemie International Edition, EarlyView.
Recent discoveries have shown that single‐stranded long‐chain nucleic acids can undergo temperature‐induced phase separation, enabling formation of micrometer‐sized condensates. This Minireview discusses the current mechanistic understanding of this phenomenon, highlights strategies for controlling the physical and chemical properties of these ...
Weixiang Chen, Johann Fritzen, Andreas Walther   +2 more
wiley   +1 more source

MEK Inhibition Reduces Vascular Malformations and Gene Dysregulation in NRAS^Q61R Human Endothelial Cells. [PDF]

Pediatr Blood Cancer
Alharbi S, Wagner A, Merkle S, Pastura P, McDaniel CG, Fox D, Xu Y, Cras TDL.   +7 more
europepmc   +1 more source

Shrinkage Mitigation and Mechanical Properties of Cement‐Based Mortar With Silane‐Functionalized Hydrogels

Journal of Applied Polymer Science, EarlyView.
Schematic depiction of silane‐functionalized hydrogels utilized in this study along with chemical structures of the primary comonents (Acrylamide, N,N'‐methylenebisacrylamide, and 3‐(trimethoxysilyl) propyl methacrylate). ABSTRACT This study investigates the applications of silane‐loaded polymer hydrogels in field‐relevant cement‐based mortar intended ...
Daniel S. Hiller, Akul N. Seshadri, Christof Schröfl, Kendra A. Erk   +3 more
wiley   +1 more source

ERK phosphorylates HNRNPF to promote the proliferation and suppress the differentiation of embryonic stem cells. [PDF]

Nucleic Acids Res
Duan X, Wang Y, Zhang J, Zhao N, Hao Q, Yang X, Du X, Yang H, Liang H, Chen L.   +9 more
europepmc   +1 more source