Results 271 to 280 of about 511,445 (325)

The Complex Role of MAPK/ERK Signaling Pathway in Different Types of Thrombocytopenia. [PDF]

Curr Issues Mol Biol
Xue P, Chen M.
europepmc   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

WISP-3 facilitates CCL4-dependent monocyte migration and M1 polarization in rheumatoid arthritis by inhibiting miR-6894-5p. [PDF]

Int J Med Sci
Wang GS, Lee KT, Lin SL, Hou SM, Fong YC, Tang CH, Lin CY.   +6 more
europepmc   +1 more source

2D copper nanozyme patches facilitate bone regeneration via interfacial modulation of osteoclast‐osteoblast dynamics

BMEMat, EarlyView.
This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen, Haoyue Hu, Danyang Wang, Ying Wang, Zhibang Li, Xiaoyi Liu, Yandi Zhang, Junkun Feng, Weiwei Zhao, Kai Li, Qi‐Zhi Zhong, Shaohua Ge, Jianhua Li   +12 more
wiley   +1 more source

NX-1607: lifting the Cbl-b brake to promote T cell activation through MAPK/ERK pathways. [PDF]

J Immunother Cancer
To A, Sugimura R.
europepmc   +1 more source

Impacts of large herbivores on mycorrhizal fungal communities across the Arctic

Ecography, EarlyView.
Mycorrhizal fungi play an integral role in nutrient and carbon cycling in soils, which may be especially important in the Arctic, one of the world's most soil carbon‐rich regions. Large mammalian herbivores can influence these fungi through their impacts on vegetation and soil conditions, however the strength and prevalence of these interactions in the
Cole G. Brachmann, Martin Ryberg, Brendan R. Furneaux, Anna Rosling, Tinghai Ou, Alf Ekblad, Svetlana Abdulmanova, Isabel C. Barrio, M. Syndonia Bret‐Harte, Hannu Fritze, Laura Gough, Robert D. Hollister, Ingibjörg S. Jónsdóttir, Oula Kalttopää, Elin Lindén, Päivi Mäkiranta, Johan Olofsson, Rauni Partanen, Kirsten A. Reid, Aleksandr Sokolov, Maija S. Sujala, Maja K. Sundqvist, Otso Suominen, Craig E. Tweedie, Amanda Young, Robert G. Björk   +25 more
wiley   +1 more source

FGF-23 facilitates osteosarcoma metastasis by modulating the miR-4463/LOXL2 axis expression via the ERK, p38, and JNK signaling pathway. [PDF]

Int J Med Sci
Hou CH, Lin CY.
europepmc   +1 more source

Insulinlike growth factor 1 receptor correlates with verbal memory in ILAE type 2 hippocampal sclerosis

Epilepsia, EarlyView.
Abstract Objective Long‐term memory deficits are often seen in patients with temporal lobe epilepsy (TLE). Recently, studies showed that patients with hippocampal sclerosis (HS) type 2, which presents with severe neuron loss in CA1 only, performed within the normal range. However, up to 30% of HS type 2 cases have memory deficits.
Henrique Cruz, Amauri Batista de Oliveira‐Júnior, André Fernando Garcia Cortez, Ricardo Lutzky Saute, Ricardo Silva Centeno, Joao Norberto Stávale, Mirian Salvadori Bittar Guaranha, Elza Marcia Targas Yacubian, Esper Abrão Cavalheiro, Joao Pereira Leite, Jose Eduardo Peixoto‐Santos   +10 more
wiley   +1 more source

Dual-specificity phosphatase 6 interferes with the repressive activity of forkhead box O1 towards CYP4A11 that mediates lipid accumulation in the liver. [PDF]

Sci Rep
Kimura M, Saiki Y, Iwata K, Murakami K, Furukawa T.   +4 more
europepmc   +1 more source