Myelodysplastic Syndrome (MDS) With <i>KMT2A::CBL</i> Rapidly Progressed to Acute Myeloid Leukaemia (AML). [PDF]
eJHaem, Volume 7, Issue 2, April 2026.
Xu K, Boneva T, Nacheva E.
europepmc +2 more sources
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
β-Thalassaemia results from defects in β-globin chain production, leading to ineffective erythropoiesis and subsequently to severe anaemia and other complications.
Pornthip Chaichompoo +9 more
doaj +1 more source
In recent years, research has revealed a wide variety of erythroid cell functions, including modulation of innate and adaptive immune responses. Anemic or hypoxic stress stimulates a physiological response in the form of stress erythropoiesis, aimed at ...
Yu. A. Shevchenko +2 more
doaj +1 more source
Antitumor properties of nuclear erythroid cells
Purpose. To study suppressor and/or cytotoxic activity of the nuclear erythroid cells (NEC) against tumor cells of various origins. Material and Methods. C57Bl/6 mice and P815, L1210, B16 and L929 tumor cells were used.
V. A. Kozlov +4 more
doaj +1 more source
Erythropoiesis is one of the most efficient cellular processes in the human body producing approximately 2.5 million red blood cells every second.
Lea A. Hampton-O’Neil +5 more
doaj +1 more source
Studies on reticuloendothelial system and hemato-poiesis, III. Relationship between differentiation of erythroblast and oxygen tension [PDF]
For the purpose to clarify the control mechanism of erythroid cell differentiation, the author observed morphologic changes in bone-marrow cells and circulating red cells in phenylhydrazine anemia of rabbits by introducing a mass of red cells into vein ...
Matsuoka, Kenichi
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Studies on erythropoiesis II. In vitro studies on red cell proliferation under varied oxygen tension [PDF]
For the purpose to reveal the mechanism of the stimulated erythropoiesis in anemic condition, the author observed the numerical changes of the erythroblasts from normal rabbit bone marrow cultured under the environment of varied oxygen tensions, and ...
Shibata, Takashi
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Vascular remodeling of the mouse yolk sac requires hemodynamic force [PDF]
The embryonic heart and vessels are dynamic and form and remodel while functional. Much has been learned about the genetic mechanisms underlying the development of the cardiovascular system, but we are just beginning to understand how changes in heart ...
Chen, Ju +5 more
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Studies on the relation between heme and nucleic acid syntheses in erythroid cell. II. Nucleic acid synthesis in erythroblast of anemic rat treated with aminopterin and bromouracil [PDF]
With the bone marrow of anemic rats, which had received the repeated injections of phenylhydrazine once a day for three to four days, the effects of aminopterin and bromouracil on the nucleic acid metabolism of erythroblasts were observed in vivo ...
Shigehisa, Morio
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