Results 21 to 30 of about 29,567 (256)

Cannibalized erythroblasts accelerate developmental neurogenesis by regulating mitochondrial dynamics

Cell Reports, 2021
Summary: Metabolic support was long considered to be the only developmental function of hematopoiesis, a view that is gradually changing. Here, we disclose a mechanism triggered during neurulation that programs brain development by donation of ...
Şükran Özsoy, Filip Vujovic, Mary Simonian, Valentina Valova, Neil Hunter, Ramin M. Farahani   +5 more
doaj   +1 more source

Wdr26 regulates nuclear condensation in developing erythroblasts.

Blood, 2020
Mammalian red blood cells lack nuclei. The molecular mechanisms underlying erythroblast nuclear condensation and enucleation, however, remain poorly understood.
Ru Zhen, Chingyee Moo, Zhenzhen Zhao, Mengying Chen, Heyuan Feng, Xiaojun Zheng, Liang Zhang, Jiahai Shi, Caiyong Chen   +8 more
semanticscholar   +1 more source

Estimating biological reference intervals for cell blood counts in a dog population

Revista Colombiana de Ciencias Pecuarias, 2020
Background: The results from automated equipment and peripheral blood smears allow correlating clinical data with cellular blood counts (CBC), generating information on pathologies of hematological and non-hematological origin in dogs.
Valentina Ochoa-Ruíz, Víctor D. Velasco-Pérez, Margarita Patiño, Jhonatan S. Restrepo-León, Jannet Zapata-Bailarín, Nathalia M. Correa-Valencia, Patricia E. Jaramillo-Arbeláez   +6 more
doaj   +1 more source

Increased autophagy leads to decreased apoptosis during β-thalassaemic mouse and patient erythropoiesis

Scientific Reports, 2022
β-Thalassaemia results from defects in β-globin chain production, leading to ineffective erythropoiesis and subsequently to severe anaemia and other complications.
Pornthip Chaichompoo, Ramaneeya Nithipongvanitch, Wasinee Kheansaard, Alisa Tubsuwan, Kanitta Srinoun, Jim Vadolas, Suthat Fucharoen, Duncan R. Smith, Pranee Winichagoon, Saovaros Svasti   +9 more
doaj   +1 more source

Study of phenotypic and cytotoxic properties of erythroid cells of the spleen under hematopoiesis-stimulating effects

Медицинская иммунология, 2023
In recent years, research has revealed a wide variety of erythroid cell functions, including modulation of innate and adaptive immune responses. Anemic or hypoxic stress stimulates a physiological response in the form of stress erythropoiesis, aimed at ...
Yu. A. Shevchenko, K. V. Nazarov, S. V. Sennikov   +2 more
doaj   +1 more source

Plasmodium falciparum sexual parasites develop in human erythroblasts and affect erythropoiesis.

Blood, 2020
Plasmodium falciparum gametocytes, the sexual stages responsible for malaria parasites transmission from humans to mosquitoes, are key targets for malaria elimination.
Gaëlle Neveu, Cyrielle Richard, Florian Dupuy, P. Behera, Fiona Volpe, Pradeep Annamalai Subramani, Benjamin Marcel-Zerrougui, Patrice Vallin, M. Andrieu, Aruna Mukti Minz, N. Azar, R. M. Martins, A. Lorthiois, F. Gazeau, Jose-Juan Lopez-Rubio, D. Mazier, A. Silva, S. Satpathi, S. Wassmer, F. Verdier, C. Lavazec   +20 more
semanticscholar   +1 more source

Antitumor properties of nuclear erythroid cells

Сибирский онкологический журнал, 2022
Purpose. To study suppressor and/or cytotoxic activity of the nuclear erythroid cells (NEC) against tumor cells of various origins. Material and Methods. C57Bl/6 mice and P815, L1210, B16 and L929 tumor cells were used.
V. A. Kozlov, G. V. Seledtsova, A. B. Dorzhieva, I. P. Ivanova, V. I. Seledtsov   +4 more
doaj   +1 more source

Inside Out Integrin Activation Mediated by PIEZO1 Signaling in Erythroblasts

Frontiers in Physiology, 2020
The non-selective mechanosensitive ion channel PIEZO1 controls erythrocyte volume homeostasis. Different missense gain-of-function mutations in PIEZO1 gene have been identified that cause Hereditary Xerocytosis (HX), a rare autosomal dominant haemolytic ...
Francesca Aglialoro, Naomi Hofsink, M. Hofman, Nicole Brandhorst, E. van den Akker   +4 more
semanticscholar   +1 more source

Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts

Scientific Reports, 2020
The molecular mechanisms involved in the terminal differentiation of erythroblasts have been elucidated by comparing enucleation and cell division. Although various similarities and differences between erythroblast enucleation and cytokinesis have been ...
Kumi Ubukawa, Tatsufumi Goto, Ken Asanuma, Yumi Sasaki, Yong-Mei Guo, Isuzu Kobayashi, K. Sawada, H. Wakui, N. Takahashi   +8 more
semanticscholar   +1 more source

Studies on reticuloendothelial system and hemato-poiesis, III. Relationship between differentiation of erythroblast and oxygen tension [PDF]

, 1965
For the purpose to clarify the control mechanism of erythroid cell differentiation, the author observed morphologic changes in bone-marrow cells and circulating red cells in phenylhydrazine anemia of rabbits by introducing a mass of red cells into vein ...
Matsuoka, Kenichi
core   +1 more source