Results 41 to 50 of about 29,567 (256)
A mechanism of ineffective erythropoiesis in β-thalassemia/Hb E disease
Haematologica, 2010 Background Cells respond to stress stimuli through a number of response pathways, of which one of the most important and well characterized is the unfolded protein response.
Pathrapol Lithanatudom +5 more
doaj +1 more source
Transferrin-polycation conjugates as carriers for DNA uptake into cells. [PDF]
, 1990 We have developed a high-efficiency nucleic acid delivery system that uses receptor-mediated endocytosis to carry DNA macromolecules into cells. We accomplished this by conjugating the iron-transport protein transferrin to polycations that bind nucleic ...
Beug, Hartmut +4 more
core +1 more source
Haematologica, 2010 The study of human erythropoiesis in health and disease requires a robust culture system that consistently and reliably generates large numbers of immature erythroblasts that can be induced to differentiate synchronously.
Emile van den Akker +4 more
doaj +1 more source
STAR Protocols, 2022 Summary: This protocol describes the generation and characterization of human induced pluripotent stem cells (hiPSCs) from erythroblasts. A key difference with classical protocols is the reprogramming of erythroblasts from a simple blood draw as opposed ...
Sylvain Perriot +3 more
doaj +1 more source
Blood, 2019 The erythroblastic island (EI), formed by a central macrophage and developing erythroblasts (EBs), was first described decades ago and was recently shown to play an in vivo role in homeostatic and pathological erythropoiesis.
Qiaozhi Wei +5 more
semanticscholar +1 more source
Studies on erythropoiesis II. In vitro studies on red cell proliferation under varied oxygen tension [PDF]
, 1964 For the purpose to reveal the mechanism of the stimulated erythropoiesis in anemic condition, the author observed the numerical changes of the erythroblasts from normal rabbit bone marrow cultured under the environment of varied oxygen tensions, and ...
Shibata, Takashi
core +1 more source
Journal of Veterinary Research, 2018 Introduction: Bisphenol A (BPA) is a substance widely used in industry for the production of polycarbonates and epoxy resins used in packaging and containers for beverages, contact lenses, compact discs (CDs), window panes, and many other elements.
Snarska Anna +4 more
doaj +1 more source
Purification of erythroblastic nests [PDF]
Blood, 1981 We describe a method for preparing purified erythroblastic nests in large numbers (approximately 10(6)/run) in three steps: (1) induction of splenic erythropoiesis in mice, (2) preparative differential centrifugation for the removal of erythrocytes and single cells from spleen cell suspensions, and (3) sedimentation in an isokinetic gradient of Ficoll ...
A J, Macario +3 more
openaire +3 more sources
Methods and Protocols, 2020 During erythropoiesis, the molecular chaperone alpha-hemoglobin-stabilizing protein (AHSP) sequesters free alpha-hemoglobin (αHb) and prevents precipitation of excess αHb.
Julia Walczak +2 more
doaj +1 more source
Iron metabolism of intestinal mucosa in various blood diseases [PDF]
, 1964 For the investigation of iron metabolism in the intestinal mucosa in various blood diseases, intestinal biopsy (duodenum) was performed on 10 healthy controls and 35 cases with various blood diseases.
Kimura, Ikuro +2 more
core +1 more source