P. falciparum Invasion and Erythrocyte Aging
CellsPlasmodium parasites need to find red blood cells (RBCs) that, on the one hand, expose receptors for the pathogen ligands and, on the other hand, maintain the right geometry to facilitate merozoite attachment and entry into the red blood cell.
María Fernanda Alves-Rosa +4 more
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The Plasmodium berghei merozoite protein PbGAC is critically involved in erythrocyte binding during invasion [PDF]
Parasites & VectorsBackground The invasion of Plasmodium merozoites into host erythrocytes is initiated through specific ligand–receptor interactions. This interaction results in subsequent invasion events, facilitated by the formation of a moving junction via AMA-1 and ...
Junying Gao +6 more
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An essential dual-function complex mediates erythrocyte invasion and channel-mediated nutrient uptake in malaria parasites [PDF]
eLife, 2017 Malaria parasites evade immune detection by growth and replication within erythrocytes. After erythrocyte invasion, the intracellular pathogen must increase host cell uptake of nutrients from plasma.
Daisuke Ito +2 more
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A Thioredoxin Homologous Protein of Plasmodium falciparum Participates in Erythrocyte Invasion [PDF]
Infection and Immunity, 2018 Huijun Lu, Dongchao Zhang, Kai Zhang
exaly +2 more sources
RBC barcoding allows for the study of erythrocyte population dynamics and P. falciparum merozoite invasion. [PDF]
PLoS ONE, 2014 Plasmodium falciparum invasion of host erythrocytes is essential for the propagation of the blood stage of malaria infection. Additionally, the brief extracellular merozoite stage of P.
Martha A Clark +5 more
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Rodent Malaria Erythrocyte Preference Assessment by an Ex Vivo Tropism Assay
Frontiers in Cellular and Infection Microbiology, 2021 Circulating red blood cells consist of young erythrocytes (early and late reticulocytes) and mature erythrocytes (normocytes). The human malaria parasites, Plasmodium falciparum and P.
Yew Wai Leong +8 more
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Invasion of Erythrocytes by Francisella tularensis [PDF]
The Journal of Infectious Diseases, 2011 Francisella tularensis is the causative agent of tularemia and is classified as a category A biodefense agent by the Centers for Disease Control and Prevention because of its highly infectious nature. F. tularensis infects leukocytes and exhibits an extracellular phase in the blood of the host. It is unknown, however, whether F.
Joseph, Horzempa +5 more
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Plasmodium falciparum reticulocyte binding-like homologue protein 2 (PfRH2) is a key adhesive molecule involved in erythrocyte invasion. [PDF]
PLoS ONE, 2011 Erythrocyte invasion by Plasmodium merozoites is a complex, multistep process that is mediated by a number of parasite ligand-erythrocyte receptor interactions. One such family of parasite ligands includes the P. falciparum reticulocyte binding homologue
Tajali Sahar +6 more
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Identification and characterization of a novel Plasmodium falciparum adhesin involved in erythrocyte invasion. [PDF]
PLoS ONE, 2013 Malaria remains a major health problem worldwide. All clinical symptoms of malaria are attributed to the asexual blood stages of the parasite life cycle. Proteins resident in apical organelles and present on the surface of P.
Nidhi Hans +5 more
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Erythrocyte tropism of malarial parasites: The reticulocyte appeal
Frontiers in Microbiology, 2022 Erythrocytes are formed from the enucleation of erythroblasts in the bone marrow, and as erythrocytes develop from immature reticulocytes into mature normocytes, they undergo extensive cellular changes through their passage in the blood. During the blood
Yew Wai Leong +6 more
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