Results 11 to 20 of about 393,416 (146)

The Role and Mechanism of Erythrocyte Invasion by Francisella tularensis [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
Francisella tularensis is an extremely virulent bacterium that can be transmitted naturally by blood sucking arthropods. During mammalian infection, F. tularensis infects numerous types of host cells, including erythrocytes.
Deanna M. Schmitt, Rebecca Barnes, Taylor Rogerson, Ashley Haught, Leanne K. Mazzella, Matthew Ford, Tricia Gilson, James W.-M. Birch, Anders Sjöstedt, Douglas S. Reed, Jonathan M. Franks, Donna B. Stolz, James Denvir, Jun Fan, Swanthana Rekulapally, Donald A. Primerano, Joseph Horzempa   +16 more
doaj   +6 more sources

Host-pathogen interactions involved in erythrocyte invasion by Francisella tularensis [PDF]

Frontiers in Cellular and Infection Microbiology
Francisella tularensis is a gram negative, facultative intracellular bacterium that causes the zoonotic disease tularemia. F. tularensis is capable of invading mammalian erythrocytes, a phenomenon that enhances colonization of ticks following a blood ...
Rori M. Schreiber, Luke D’Cunha, Mackenzie Hall, Anthony DeBastiani, Deanna M. Schmitt, Stuart Cantlay, Joseph Horzempa   +6 more
doaj   +2 more sources

P. falciparum Invasion and Erythrocyte Aging

Cells
Plasmodium parasites need to find red blood cells (RBCs) that, on the one hand, expose receptors for the pathogen ligands and, on the other hand, maintain the right geometry to facilitate merozoite attachment and entry into the red blood cell.
María Fernanda Alves-Rosa, Nicole M. Tayler, Doriana Dorta, Lorena M. Coronado, Carmenza Spadafora   +4 more
doaj   +3 more sources

Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion.

PLoS Pathogens, 2007
The process of erythrocyte invasion by merozoites of Plasmodium falciparum involves multiple steps, including the formation of a moving junction between parasite and host cell, and it is characterised by the redundancy of many of the receptor-ligand ...
Alfred Cortés, Celine Carret, Osamu Kaneko, Brian Y S Yim Lim, Alasdair Ivens, Anthony A Holder   +5 more
doaj   +2 more sources

4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation [PDF]

Nature Communications, 2021
Here, Geoghegan, Evelyn et al. provide a lattice light-sheet microscopy based 4D imaging pipeline to quantitatively investigate Plasmodium spp. invasion and show that the nascent parasitophorous vacuole is predominantly formed from host’s erythrocyte ...
Niall D. Geoghegan, Cindy Evelyn, Lachlan W. Whitehead, Michal Pasternak, Phoebe McDonald, Tony Triglia, Danushka S. Marapana, Daryan Kempe, Jennifer K. Thompson, Michael J. Mlodzianoski, Julie Healer, Maté Biro, Alan F. Cowman, Kelly L. Rogers   +13 more
doaj   +3 more sources

Membrane-Wrapping Contributions to Malaria Parasite Invasion of the Human Erythrocyte [PDF]

Biophysical Journal, 2014
The blood stage malaria parasite, the merozoite, has a small window of opportunity during which it must successfully target and invade a human erythrocyte. The process of invasion is nonetheless remarkably rapid. To date, mechanistic models of invasion have focused predominantly on the parasite actomyosin motor contribution to the energetics of entry ...
Dasgupta, Sabyasachi, Auth, Thorsten, Gov, Nir S, Satchwell, Timothy J, Hanssen, Eric, Zuccala, Elizabeth S, Riglar, David T, Toye, Ashley M, Betz, Timo, Baum, Jake, Gompper, Gerhard   +10 more
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Invasion of Erythrocytes by Francisella tularensis [PDF]

The Journal of Infectious Diseases, 2011
Francisella tularensis is the causative agent of tularemia and is classified as a category A biodefense agent by the Centers for Disease Control and Prevention because of its highly infectious nature. F. tularensis infects leukocytes and exhibits an extracellular phase in the blood of the host. It is unknown, however, whether F.
Joseph, Horzempa, Dawn M, O'Dee, Donna Beer, Stolz, Jonathan M, Franks, Doris, Clay, Gerard J, Nau   +5 more
openaire   +2 more sources

The PfRCR complex bridges malaria parasite and erythrocyte during invasion [PDF]

, 2023
The symptoms of malaria occur during the blood stage of infection, when parasites invade and replicate within human erythrocytes. The PfPCRCR complex1, containing PfRH5 (refs.
Walters-Morgan, Hannah, Ragotte, Robert J., Farrell, Brendan, Draper, Simon J., Alam, Nawsad, Hart, Melissa N., Higgins, Matthew K., Knuepfer, Ellen, Jamwal, Abhishek   +8 more
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Expression of Plasmodium falciparum genes involved in erythrocyte invasion varies among isolates cultured directly from patients. [PDF]

, 2006
Plasmodium falciparum merozoites invade erythrocytes using a range of alternative ligands that includes erythrocyte binding antigenic proteins (EBAs) and reticulocyte binding protein homologues (Rh).
Conway, David J, Deans, Anne-Marie, Mosobo, M, Conway, DJ, Conway, David J., Rowe, J. Alexandra, Rowe, J Alexandra; id_orcid, Mosobo, Moses, Marsh, Kevin, Deans, AM, Rowe, J Alexandra, Nery, S, Nery, Susana, Rowe, JA   +13 more
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Invasion pathways and malaria severity in Kenyan Plasmodium falciparum clinical isolates. [PDF]

, 2007
The invasion of erythrocytes by Plasmodium falciparum occurs through multiple pathways that can be studied in vitro by examining the invasion of erythrocytes treated with enzymes such as neuraminidase, trypsin, and chymotrypsin.
Kai, Oscar, Conway, David J, Deans, Anne-Marie, Conway, David J., Rowe, J. Alexandra, Rowe, J Alexandra; id_orcid, Marsh, Kevin, Rowe, J Alexandra, Nery, Susana   +8 more
core   +1 more source