Results 41 to 50 of about 393,416 (146)

Non-invasive measurement of erythrocyte zinc protoporphyrin in children [PDF]

Pediatric Research, 2018
Reliable screening for iron deficiency (ID) has required a blood sample and cost-intensive laboratory measurements. A novel method to non-invasively measure erythrocyte zinc protoporphyrin (ZnPP), an established marker for ID, is evaluated in children.ZnPP was determined non-invasively by fluorescence measurements on the wet vermillion of the lower lip
Christian, Homann, Georg, Hennig, Felicitas, Maier, Herbert, Stepp, Lesca M, Holdt, Michael, Vogeser, Ronald, Sroka, Berthold, Koletzko   +7 more
openaire   +2 more sources

Generation of Plasmodium falciparum parasite-inhibitory antibodies by immunization with recombinantly-expressed CyRPA [PDF]

, 2016
The pathogenesis of malaria is primarily associated with blood-stage infection and there is strong evidence that antibodies specific for parasite blood-stage antigens can control parasitaemia. This provides a strong rationale for incorporation of asexual
Marco Tamborrini (2280460), Hugues Matile (412555), Ralf Thoma, Gerd Pluschke, Matile, Hugues, Thoma, Ralf, Riccio, Guy, Hugues Matile, Dreyer, Anita M., Paola Favuzza (3474788), Gerd Pluschke (7855), Blaser, Simon, Tamborrini, Marco, Simon Blaser, Guy Riccio, Anita Dreyer (691164), Ralf Thoma (1870957), Paola Favuzza, Anita M. Dreyer, Marco Tamborrini, Simon Blaser (3474785), Favuzza, Paola, Pluschke, Gerd, Guy Riccio (3474782), Blaser S, Favuzza P, Dreyer AM, Pluschke G, Riccio G, Matile H, Tamborrini M, Thoma R   +31 more
core   +1 more source

Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasites

eLife, 2021
Invasion of human erythrocytes by the malaria parasite Plasmodium falciparum is a multi-step process. Previously, a forward genetic screen for P. falciparum host factors identified erythrocyte CD55 as essential for invasion, but its specific role and how
Bikash Shakya, Saurabh D Patel, Yoshihiko Tani, Elizabeth S Egan   +3 more
doaj   +1 more source

Plasmodium falciparum variant STEVOR antigens are expressed in merozoites and possibly associated with erythrocyte invasion

Malaria Journal, 2008
Background Plasmodium falciparum STEVOR proteins, encoded by the multicopy stevor gene family have no known biological functions. Their expression and unique locations in different parasite life cycle stages evoke multiple functionalities.
Petter Michaela, Schreiber Nadine, Bonow Insa, Khattab Ayman, Schmetz Christel, Klinkert Mo-Quen   +5 more
doaj   +1 more source

Plasmodium falciparum erythrocyte binding antigen-175 triggers a biophysical change in the red blood cell that facilitates invasion [PDF]

, 2017
Invasion of the red blood cell (RBC) by the Plasmodium parasite defines the start of malaria disease pathogenesis. To date, experimental investigations into invasion have focused predominantly on the role of parasite adhesins or signaling pathways and ...
Herbig, M, Maik Herbig, Otto, O., Guck, J, Guck, Jochen, Wright, K., Satchwell, Tim, Baum, J., Salinas, Nichole D., Tolia, N., Koch, M, Satchwell, TJ, Brooks, N., Baum, Jake, Nicholas J. Brooks, Jake Baum, Jochen Guck, Koch, M., Otto, Oliver, Tolia, Niraj H., Oliver Otto, Guck, J., Nichole D. Salinas, Herbig, M., Marion Koch, Satchwell, Timothy J., Brooks, N, Niraj H. Tolia, Herbig, Maik, Tolia, NH, Wright, KE, Timothy J. Satchwell, Brooks, Nicholas J., Salinas, ND, Otti, O, Wright, Katherine E., Koch, Marion, Satchwell, T., Salinas, N., Baum, J, Katherine E. Wright   +40 more
core   +1 more source

Distribution of malaria parasite-derived phosphatidylcholine in the infected erythrocyte

mSphere, 2023
Malaria parasites modify their host erythrocyte in multiple ways, leading to changes in the deformability, adhesiveness, and permeability of the host erythrocyte.
Tansy Vallintine, Christiaan van Ooij
doaj   +1 more source

Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion

Blood, 2023
Abstract The malaria parasite Plasmodium falciparum invades and replicates asexually within human erythrocytes. CD44 expressed on erythrocytes was previously identified as an important host factor for P falciparum infection through a forward genetic screen, but little is known about its regulation or function in these cells, nor how it ...
Barbara Baro, Chi Yong Kim, Carrie Lin, Angel K. Kongsomboonvech, Marilou Tetard, Nana Ansuah Peterson, Nichole D. Salinas, Niraj H. Tolia, Elizabeth S. Egan   +8 more
openaire   +2 more sources

The Trw Type IV Secretion System of Bartonella Mediates Host-Specific Adhesion to Erythrocytes [PDF]

, 2010
Bacterial pathogens typically infect only a limited range of hosts; however, the genetic mechanisms governing host-specificity are poorly understood.
Danchin, Antoine, Philipp Engel, Dehio, Christoph, Quebatte, Maxime, Le Rhun, Danielle, Vayssier-Taussat Muriel, Maxime Quebatte, Saenz, Henri, Lionel Arnaud, Mavris, Arnaud Lionel, Lenaour Evelyne, Yang, Huanming, Sandra Cescau, Wang Jing, Mavris, Maria, Lenaour, Evelyne, Boulouis, Henri Jean, Taussat, Muriel, Antoine Danchin, Vayssier-Taussat, Muriel, Deng Hong Kuan, Jing Wang, Huanming Yang, Boulouis Henri Jean, Arnaud, Lionel, Quebatte Maxime, Engel, Philipp, Le Naour, Evelyne, Muriel Vayssier-Taussat, Henri Saenz, Maria Mavris, Dehio Christoph, Biville Francis, Danielle Le Rhun, Le Rhun Danielle, Danchin Antoine, Francis Biville, Christoph Dehio, Biville, Francis, Geneviève Marignac, Yang Huanming, Engel Philipp, Hong Kuan Deng, Cescau Sandra, Evelyne Lenaour, Mavris Maria, Deng, H.K., Deng, Hong Kuan, Wang, Jing, Marignac Geneviève, Cescau, Sandra, Marignac, Geneviève, Boulouis, Henri-Jean, Henri Jean Boulouis, Arnaud Lionel, Saenz Henri   +55 more
core   +1 more source

An ApiAP2 Family Transcriptional Factor PfAP2-06B Regulates Erythrocyte Invasion Indirectly in Plasmodium falciparum

Pathogens
Obligate intracellular parasites must efficiently invade host cells to complete their life cycle and facilitate transmission. For the malaria-causing parasite Plasmodium falciparum, the invasion of an erythrocyte is a critical process, and thereby a key ...
Qiyang Shi, Kai Wan, Yifei Gong, Jiayao Pang, Yaobao Liu, Jianxia Tang, Qingfeng Zhang, Jun Cao, Li Shen   +8 more
doaj   +1 more source

Biochemical and functional analysis of two Plasmodium falciparum blood-stage 6-cys proteins: P12 and P41. [PDF]

PLoS ONE, 2012
The genomes of Plasmodium parasites that cause malaria in humans, other primates, birds, and rodents all encode multiple 6-cys proteins. Distinct 6-cys protein family members reside on the surface at each extracellular life cycle stage and those on the ...
Tana Taechalertpaisarn, Cecile Crosnier, S Josefin Bartholdson, Anthony N Hodder, Jenny Thompson, Leyla Y Bustamante, Danny W Wilson, Paul R Sanders, Gavin J Wright, Julian C Rayner, Alan F Cowman, Paul R Gilson, Brendan S Crabb   +12 more
doaj   +1 more source