Results 21 to 30 of about 393,416 (146)

Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]

, 2014
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
Paul C. Divis (615586), Lynch, Sean, Ahmed Atique M., Wong, Ing Tien, Scott B. Millar, Scott B, Millar, Scott B Millar, Ahmed, Atique M., Paul C Divis, Chan Woon Lu (615590), Janet Cox-Singh (218129), Divis Paul C., Singh Balbir, Siner Angela, Balbir, Singh, Singh, Balbir, Miguel M. Pinheiro, Janet Cox-Singh, Ahmed, AM, Singh, B, Balbir Singh, Wong Ing Tien, Janet, Cox-Singh, Singh-Khaira, Sarina K., Millar, SB, Ramlah Zainudin (615588), Matthias, Willmann, Lynch, S, Ing Tien Wong (615589), Wong, IT, Scott B. Millar (615592), Ing Tien Wong, Sanjeev Krishna (4917), Siner, A, Paul C, Divis, Miguel M. Pinheiro (615585), Pinheiro, MM, Matthias Willmann (615594), Sanjeev, Krishna, Lu, CW, Atique M. Ahmed (615584), Millar Scott B., Atique M Ahmed, Lynch Sean, Atique M, Ahmed, Sanjeev Krishna, Sean Lynch (615593), Monsanto Pinheiro, Miguel, Sarina K Singh-Khaira, Pinheiro Miguel M., Lu Chan Woon, Cox-Singh, J, Miguel M, Pinheiro, Zainudin, Ramlah, Divis, Paul C., Siner, Angela, Cox-Singh, Janet, Miguel M Pinheiro, Balbir Singh (218132), Willmann, M, Zainudin Ramlah, Willmann, Matthias, Tien, Wong, Sean Lynch, Paul C. Divis, Millar, Scott B., Cox-Singh Janet, Atique M. Ahmed, Sarina K, Singh-Khaira, Chan Woon Lu, Krishna Sanjeev, Zainudin, R, Lu, Chan Woon, Sarina K. Singh-Khaira, Angela Siner, Cox Singh, Janet, Singh-Khaira Sarina K., Singh-Khaira, SK, Willmann Matthias, Ramlah, Zainudin, Matthias Willmann, Chan, Woon Lu, Angela, Siner, Krishna, S, Sean, Lynch, Krishna, Sanjeev, Angela Siner (615587), Sarina K. Singh-Khaira (615591), Ramlah Zainudin, Pinheiro, Miguel M., Divis, PC, Cox Singh, Janet; id_orcid   +91 more
core   +2 more sources

PdpC, a secreted effector protein of the type six secretion system, is required for erythrocyte invasion by Francisella tularensis LVS

Frontiers in Cellular and Infection Microbiology, 2022
Francisella tularensis is a gram negative, intracellular pathogen that is the causative agent of the potentially fatal disease, tularemia. During infection, F. tularensis is engulfed by and replicates within host macrophages. Additionally, this bacterium
Stuart Cantlay, Christian Kaftanic, Joseph Horzempa   +2 more
doaj   +1 more source

Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites. [PDF]

PLoS Pathogens, 2008
Invasion by the malaria merozoite depends on recognition of specific erythrocyte surface receptors by parasite ligands. Plasmodium falciparum uses multiple ligands, including at least two gene families, reticulocyte binding protein homologues (RBLs) and ...
Xiaohong Gao, Kim Pin Yeo, Siqi Sharon Aw, Claudia Kuss, Jayasree K Iyer, Saraswathy Genesan, Ravikumar Rajamanonmani, Julien Lescar, Zbynek Bozdech, Peter R Preiser   +9 more
doaj   +1 more source

Genome sequencing of chimpanzee malaria parasites reveals possible pathways of adaptation to human hosts. [PDF]

, 2014
Plasmodium falciparum causes most human malaria deaths, having prehistorically evolved from parasites of African Great Apes. Here we explore the genomic basis of P.
Conway, David J, Conway, David J., Ollomo, Benjamin, Ollomo, B., Böhme, Ulrike, Berriman, Matthew, Thomas, A. W., Bohme, U., Rayner, Julian C., Otto, Thomas D, Rayner, Julian C, Otto, Thomas D., Spottiswoode, N., Newbold, C., Otto, T. D., Pain, A., Pain, Arnab, Thomas, Alan W., Rayner, J. C., Berriman, M., Sanders, M., Conway, D. J., Renaud, F., Sanders, Mandy, Quail, Michael, Renaud, François, Quail, M., Thomas, Alan W, Spottiswoode, Natasha, Newbold, Chris, Prugnolle, Franck   +30 more
core   +1 more source

Invasion and persistent intracellular colonization of erythrocytes : A unique parasitic strategy of the emerging pathogen Bartonella [PDF]

, 2001
The expanding genus Bartonella includes zoonotic and human-specific pathogens that can cause a wide range of clinical manifestations. A productive infection allowing bacterial transmission by blood-sucking arthropods is marked by an intraerythrocytic ...
Schulein, R., Gille, C., Yves Hansmann, Hansmann, Y., Dehio, C., Seubert, A., Piemont, Y., Yves Piémont, Christa Lanz, Ralf Schülein, Anja Seubert, Lanz, C., Christoph Dehio, Christian Gille, Hansmann Y, Piémont Y, Gille C, Seubert A, Schülein R, Dehio C, Lanz C   +20 more
core   +1 more source

Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake

eLife, 2021
Malaria parasites use the RhopH complex for erythrocyte invasion and channel-mediated nutrient uptake. As the member proteins are unique to Plasmodium spp., how they interact and traffic through subcellular sites to serve these essential functions is ...
Marc A Schureck, Joseph E Darling, Alan Merk, Jinfeng Shao, Geervani Daggupati, Prakash Srinivasan, Paul Dominic B Olinares, Michael P Rout, Brian T Chait, Kurt Wollenberg, Sriram Subramaniam, Sanjay A Desai   +11 more
doaj   +1 more source

The effects of dyslipidaemia and cholesterol modulation on erythrocyte susceptibility to malaria parasite infection

Malaria Journal, 2019
Background Malaria disease commences when blood-stage parasites, called merozoites, invade human erythrocytes. Whilst the process of invasion is traditionally seen as being entirely merozoite-driven, emerging data suggests erythrocyte biophysical ...
Marion Koch, Jaimini Cegla, Ben Jones, Yuning Lu, Ziad Mallat, Andrew M. Blagborough, Fiona Angrisano, Jake Baum   +7 more
doaj   +1 more source

Crystal structure of PfRh5, an essential P. falciparum ligand for invasion of human erythrocytes

eLife, 2014
Plasmodium falciparum causes the most severe form of malaria in humans and is responsible for over 700,000 deaths annually. It is an obligate intracellular parasite and invades erythrocytes where it grows in a relatively protected niche.
Lin Chen, Yibin Xu, Julie Healer, Jenny K Thompson, Brian J Smith, Michael C Lawrence, Alan F Cowman   +6 more
doaj   +1 more source

Recent increase in low complexity polygenomic infections and sialic acid-independent invasion pathways in Plasmodium falciparum from Western Gambia

Parasites & Vectors, 2023
Background The malaria parasite Plasmodium falciparum utilizes multiple alternative receptor-ligand interactions for the invasion of human erythrocytes. While some P.
Nora Nghochuzie Nganyewo, Fatoumata Bojang, Eniyou Cheryll Oriero, Ndey Fatou Drammeh, Olumide Ajibola, Haddijatou Mbye, Aminata Seedy Jawara, Simon Corea, Gordon Akanzuwine Awandare, Umberto D’Alessandro, Lucas N. Amenga-Etego, Alfred Amambua-Ngwa   +11 more
doaj   +1 more source

Cysteine Residues in Region 6 of the Plasmodium yoelii Erythrocyte-Binding-like Ligand That Are Related to Its Localization and the Course of Infection

Biomolecules, 2023
Plasmodium malaria parasites use erythrocyte-binding-like (EBL) ligands to invade erythrocytes in their vertebrate host. EBLs are released from micronemes, which are secretory organelles located at the merozoite apical end and bind to erythrocyte surface
Hitoshi Otsuki, Osamu Kaneko, Daisuke Ito, Yoko Kondo, Hideyuki Iriko, Tomoko Ishino, Mayumi Tachibana, Takafumi Tsuboi, Motomi Torii   +8 more
doaj   +1 more source